We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Flagship initiative of Childrens Mercy Research Institute and Genomic Medicine Center in Kansas City. This research program is building pediatric data repository to facilitate search for answers and novel treatments.Goal is to collect genomic data and health information for 30,000 children and their families to create a database of genomes.
Database of non identifiable, summary data on all variants identified in Childrens Mercy Genomic Medicine Center, including project data of Genomic Answers for Kids. Database can be searched and viewed with genomic annotations, population database cross references such as ClinVar, gnomAD and dbSNP, ACMG curations and local allele frequency. Variant data are available for bulk download as annotated VCF.
Research facility based in the School of Biological Sciences and the UK Centre for Mammalian Synthetic and Systems Biology that provides proteomics and metabolomics services for qualitative and quantitative analysis.
Software package to generate Lorenz plots and Coverage plots, directly from BAM file. It can also output tables as text documents so you can generate custom plots. There is also support to only analyse specific regions.
Software tool as microbial community sample search method based on smart pair wise sample comparison without compromising accuracy. Used as microbial communities similarites calculation and comparison tool.
Web tool to visually summarise all available 3D structural information for all proteins comprising COVID-19 virus (SARS-CoV-2). Resource also gives access to structural models, generated by finding all sequence regions with detectable similarity to any currently published 3D structure. These structures are clustered into distinct states that provide insight into viral replication, mimicry, and hijacking.
Web application to help biologists use 3D structures to gain insight into protein function. Used in revealing novel insights into molecular mechanisms underlying protein function in health and disease. System for incorporating 3D structures into variant analysis.
Core is part of Edinburgh Clinical Research Facility, situated in the Centre for Cardiovascular Sciences in the Queen's Medical Research Institute. We train and host undergraduate students, PhD and post-doctoral students in practical skills and mass spectrometry operation. We have expertise in sample preparation, separation and mass spectrometry analysis for targeted small molecule analysis in clinical and pre-clinical studies. We operate under Good Clinical Practice for laboratories for clinical studies. Steroids, drugs and endogenous molecules and metabolic pathways in plasma, serum, tissue. We also have Imaging Mass spectrometry capabilities with a Waters Synapt G2Si, MALDI and DESI.
Facility offers internal and external clients experimental solutions to carry out animal studies requiring in vivo imaging, including consultations, research plan design, protocol development, data collection, analysis, and reporting. PCIC offers modalities like MRI and ultrasound enabling translational research.
Used for performing applications requiring ultimate sensitivity for ultra low level quantitation of both small and large molecules.
Software tool for modeling species niches and distributions by applying machine learning technique called maximum entropy modeling. Used for maximum entropy modelling of species geographic distributions.
Software tool for Bayesian analysis of single cell sequencing data. Used to perform statistical analyses of single cell RNA sequencing datasets in context of supervised experiments.
Software tool used to plot circular plots and visualize genomic data along genomic locations.
Software library used to tag or barcode individual cell population with unique 18 nucleotide barcodes.
Software tool to quantify comet parameters while studying DNA strand breaks. Automated tool for comet assay image analysis.
Software tool used to separate or demultiplex pooled barcodes.
Software R package used to karyoplots. Bioconductor package to plot customizable genomes displaying arbitrary data.
Software R package to help explain which variables are most important in random forests. Various variable importance measures are calculated and visualized in different settings in order to get idea on how their importance changes classification or regression model accuracy.
Software tool to detect alternative polyadenylation and identify cell type specific APA in multi cluster setting.
Software tool as fully automated pipeline for metagenomic analysis. Used for metagenomics covering all steps of analysis. Features several characteristics including co-assembly procedure or co-assembly of unlimited number of metagenomes via merging of individual assembled metagenomes, both with read mapping for estimation of abundances of genes in each metagenome. Includes binning and bin checking for retrieving individual genomes.