Curator Dashboard

Provides access to range of preclinical imaging modalities and support services. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture. Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis. Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Open source software for analysis of patch-clamp electrophysiological data. Integrated analysis environment including routines for curve fitting, post-synaptic event and action potential analyses, data resampling, filtering, detrending and more.

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• RRID-Legacy
• 5 years ago - by Anonymous

Open source software for anonymizing sensitive personal data.Supports variety of privacy and risk models, methods for transforming data and methods for analyzing usefulness of output data.

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• SciCrunch
• 5 years ago - by Anonymous

Provides either dynamic or static control of parts per million levels of nitric oxide (NO) and limits the undesirable elevation NO2 in animal models when used in combination with either one or two (1 or 2) A-Chamber Animal Chambers.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of parts per million levels of nitric oxide (NO) in animal models modeling when used in combination with either one or two (1 or 2) A-Chamber Animal Chambers.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of parts per million levels of carbon monoxide (CO) conditions in animal models modeling when used in combination with either one or two (1 or 2) A-Chamber Animal Chambers.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of O2 conditions for animal modeling when used in combination with the one to four (1-4) A-Chamber Animal Chambers.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of CO2 conditions for animal modeling when used in combination with one to four (1-4) A-Chamber Animal Chambers purposes.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of O2 and CO2 conditions for animal modeling when used in combination with one or two A-Chamber Animal Chamber(s).

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Provides either dynamic or static control of O2 condition for animal modeling when used in combination with A-Chamber Animal Chamber.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Software tool for fast and accurate protein structure prediction. Builds protein structure based on direct energy minimizations with restrained Rosetta. Restraints include inter-residue distance and orientation distributions, predicted by deep residual neural network. Homologous templates are included in network prediction to improve accuracy for easy targets.

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• RRID-Legacy
• 5 years ago - submitted by Juraj Ahel

Core offers micro 3D X-ray imaging of small samples in high resolution and provides images and quantitative analyses of internal structures of ex vivo samples without any destructive procedures.Scanco CT40 system allows for visualization, measurement, and quantification of the structure of mineralized specimens. Contrast reagents permit visualization of soft tissue structures such as blood vessels.System creates 3D model from stack of 2D X-ray images taken around single axis of rotation. High-resolution scanner can capture detail at resolution of 6 to 32 microns. Non- destructive nature of this technology allows investigators to carry out complementary analyses of the same sample. There are two dedicated workstations for analyzing microCT data, the SCANCO analysis software or the Amira software package with XImagePAQ extension.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Software Python suite to convert electron diffraction images to SMV format. Used in three dimensional electron crystallography.Developed to accomplish tasks of unit-cell determination, indexing, background subtraction, intensity measurement and merging, resulting in data that can be carried forward to molecular replacement and structure determination.

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• RRID-Legacy
• 5 years ago - by Anonymous

Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Animal Cage Enclosures for use in in vivo models that require control of experimental gases such as O2, CO2, NO, or CO. May be used together with gas controllers from BioSpherix. Chamber is outfitted with adjustable ventilation holes which permit ventilation of animal vapors and gases while simultaneously ensuring stable control of experimental conditions within. Available in three standard sizes.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Controller for live cell microscopy provides two identical streams of any mix of oxygen and carbon dioxide gas without use of premixed gas cylinders. Eliminates need for pre-mixed gas. Controller is used primarily to pre-condition perfusion media while simultaneously conditioning headspace above culture.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Hypoxia cell culture system includes hypoxia incubator and cell culture hood with glove sleeves.

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• SciCrunch
• 5 years ago - submitted by Ray Gould

Software tool to combine multiple subreads of same SMRTbell molecule using statistical model to produce one highly accurate consensus sequence, also called HiFi read, along with base quality values. This tool powers Circular Consensus Sequencing workflow in SMRT Link.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software tool to purge haplotigs and overlaps in assembly based on read depth.Used for haplotypic duplication identification. Designed to remove haplotigs and contig overlaps in a de novo assembly based on read depth.

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• RRID-Legacy
• 5 years ago - by Anonymous

Visualization and analysis software for Hi-C data.

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• RRID-Legacy
• 5 years ago - by Anonymous