We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Improved model quality assessments using Rosetta energy terms. Predictor combines training features from ProQRosCen, ProQRosFA and ProQ2.
Interactive web service for recognition of errors in three dimensional structures of proteins.
Web engine for visualizing and sharing life science datasets.Designed to organize, visualize, and enable sharing of interactive genomic data visualizations. Provides ability to inspect and interpret sequencing data, without requiring programming expertise.
Software package as collection of plugins for use in Digital Holographic Microscopy. Used for digital holographic microscopy processing in ImageJ. Main plugins include DHM Utilities Reconstruction, for reconstructing and propagating holograms; DHM Utilities Phase Unwrapping, for phase unwrapping; DHM Utilities Multi Image Landmark Correspondences, for aligning images.
Software framework for human and nonhuman brain models.Combines open database with software for access, management, and vetting, allowing scientists to distribute their resources under FAIR principles. Supports multifaceted insight into brains across species, and enables multiverse analyses testing whether results generalize across standard references, scales.Community archive of imaging templates and atlases for improved consistency in neuroimaging R.
Software tool for compressing genomes in FASTA or gzipped FASTA input format. Used for fast and efficient compression of bacteria species collections.
Platform for recognizing and promoting Open Research. Open online service that aims to offer fairer and more democratic platform for recognizing researcher contributions.Allows researchers to openly acknowledge colleagues for meaningful contributions to research process, such as Publication, Mentoring,Teaching,Data sharing,Reproducibility practices, Sharing negative results, Participation in discussion groups,Software development, Clinical trials management, Leadership, Community outreach, Public engagement. ORCID iDs, DOIs, grant IDs and other persistent identifiers are used where available as links to appropriate contributions.
Software package for working with neuronal meshes, skeletons, and annotations from electron microscopy data. Used to work with meshes, designed around use cases for analyzing neuronal morphology.
Python cloud pipeline for Neuroglancer compatible Downsampling, Meshing, Skeletonizing, Remapping, and more. TaskQueue and CloudVolume based pipeline for producing and managing visualizable Neuroglancer Precomputed volumes.Uses CloudVolume for accessing data on AWS S3, Google Storage, or local filesystem.
Software package for basic visual stimulation, imaging analysis, plotting, and cell visual response properties analysis functionality for calcium imaging.
Proteome scale collection of protein localization and interaction measurements in human cells. Proteome scale endogenous tagging enables cartography of human cellular organization.
Software tool for deep learning based approach for fully self supervised protein localization profiling and clustering. Leverages self supervised training scheme that does not require pre existing knowledge, categories, or annotations. Used for encoding protein localization patterns from microscopy images.
Consortium is creating new data driven approach to drug discovery based on cellular imaging, image analysis, and high dimensional data analytics. Creates public data set to validate and scale up this image based drug discovery strategy. By coordinating assay procedures across partners, future created data will be well matched. Aims to make cell images as computable as genomes and transcriptomes.
Software to control positioning systems without their own macro facility.
Center maintains database containing all phenotypical data collected by Research Projects and Ancillary collaborators, as well as RNAseq and genotype data.Provides access to data generated by NIDA center for genetic studies of drug abuse in outbred rats and additional research projects that use N/NIH heterogeneous stock (HS) outbred rats and Center’s core services that support genotyping and analysis.Alignes data generated in HS rats with FAIR (Findable, Accessible, Interoperative, Reusable) data management principles.Provides structured access to data associated with research papers produced by research projects that use HS rats.
Software tool fo analysis of next generation sequencing data. Calculates various summary statistics, and performs association mapping and population genetic analyses utilizing full information in next generation sequencing data by working directly on raw sequencing data or by using genotype likelihoods.
Database of metadata and assembly quality metrics for all Arthropod assemblies on NCBI.
Landscape of allele specific transcription factor binding in human genome. Creators conducted meta analysis of ChIP-Seq experiments and assembled database of allele specific binding events listing more than half million entries at nearly 270 thousand single nucleotide polymorphisms for several hundred human transcription factors and cell types.
Software tools for analysis of data independent acqusition type proteomics data are implemented in Galaxy framework. Enables complete DIA data analysis including spectral library generation based on DDA type data, analysis of DIA data in raw or mzml format, and differntial statistical analysis. All tools are based on open-source software such as diypasef, OpenSwath, swath2stats and MSstats.
Web service platform logging metadata for genomic samples and high throughput sequencing, manages data processing workflows, and provides quality control reporting and visualization. PEGR links people, samples, protocols, sequencing and bioinformatics computation to comply with FAIR best practices for publications and data management plans.Tracks and quality controls experiments from conception to publication ready figures, compatible with multiple assays and bioinformatic pipelines. It supports rigor and reproducibility for biochemists working at wet bench, while continuing to fully support reproducibility and reliability for bioinformaticians through integration with Galaxy platform.