Curator Dashboard

Service to culture various microorganisms that can be isolated from readily available sources. Assists with investigation of anaerobic processes such as glycolysis and lactic acid fermentation.

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• RRID-Legacy
• 4 years ago - submitted by Jon Matthews

Aerobic cultivation services to culture various microorganisms that can be isolated from readily available sources.

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• RRID-Legacy
• 4 years ago - submitted by Jon Matthews

Provides service for isolation and cultivation of specific bacteria connected with sequencing technology. Services include high throughput sequencing, determination of culture conditions, isolation, cultivation, purification and identification of target strain.

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• RRID-Legacy
• 4 years ago - submitted by Jon Matthews

Service for anaerobic bacteria cultivation and culture using variety of culture media and culture conditions. Includes collection, strain cultivation, isolation, identification and strain preservation.

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• RRID-Legacy
• 4 years ago - submitted by Jon Matthews

Database containing all antibody structures available in the PDB, annotated and presented in consistent fashion.Each structure is annotated with number of properties including experimental details, antibody nomenclature (e.g. heavy-light pairings), curated affinity data and sequence annotations. You can use the database to inspect individual structures, create and download datasets for analysis, search the database for structures with similar sequences to your query, monitor the known structural repetoire of antibodies.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

AAAAA aims to become the ultimate tool for antibody structural analysis, modelling and engineering.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Web tool as structure based antibody prediction server. Collection of computational tools that make predictions about properties of antibodies, focusing on their structures. Single platform containing multiple applications which can: number and align sequences; automatically generate antibody variable fragment homology models; annotate such models with estimated accuracy alongside sequence and structural properties including potential developability issues; predict paratope residues; and predict epitope patches on protein antigens.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Tracks all antibody and nanobody related therapeutics recognized by World Health Organisation, and identifies any corresponding structures in Structural Antibody Database with near exact or exact variable domain sequence matches. Synchronized with SAbDab to update weekly, reflecting new Protein Data Bank entries and availability of new sequence data published by WHO.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Web server for cancer miRNome interactive analysis and visualization based on human miRNome data of cancer types from The Cancer Genome Atlas, and public cancer circulating miRNome profiling datasets from NCBI Gene Expression Omnibus and ArrayExpress. Comprehensive database for interactive analysis and visualization of miRNA expression profiles.

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• RRID-Legacy
• 4 years ago - by Anonymous

Software pipeline to improve gene annotation for cross species analysis of single cell RNA-Seq. Cross-species transfer of high quality 3’UTR annotation for single cell RNA-Seq.

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• SciCrunch
• 4 years ago - submitted by Holger Klein

Software tool for searching metabolites in different databases including Kegg, HMDB, LipidMaps, Metlin, NP Atlas, KNApSAcK, MINE and in house library. Designed for searches through experimental masses obtained from mass spectrometry techniques. Metabolite annotation tool that uses expert system to score putative annotation based on analytical information acquired under different configurations.

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• RRID-Legacy
• 4 years ago - by Anonymous

In addition to the isolation and cultivation of pure strains, adequate preservation is also necessary. A wide variety of techniques are available for bacteria preservation. The primary aim of cultural preservation is to maintain the organism alive, uncontaminated, and without variation or mutation, that is, to preserve the culture in a condition that is as close as possible to the original isolate.

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• SciCrunch
• 4 years ago - submitted by Jon Matthews

Microorganisms can be categorized in several ways including aerobes (require oxygen to survive), facultative anaerobes (able to use oxygen for aerobic respiration but may also use fermentation or anaerobic respiration when oxygen is not present, or use fermentation in the presence of oxygen), or obligate anaerobes (cannot survive in the presence of oxygen). Some examples of facultatively anaerobic bacteria are Staphylococcus spp., Escherichia coli, Salmonella, Listeria spp., Shewanella oneidensis, and Yersinia pestis. Certain eukaryotes are also facultative anaerobes, including fungi such as Saccharomyces cerevisiae and many aquatic invertebrates such as nereid polychaetes. Culturing facultative anaerobes, however, poses a challenge for researchers because the equipment to grow, isolate, and identify them can be costly.

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• SciCrunch
• 4 years ago - submitted by Jon Matthews

Atmospheric condition is generally satisfactory for the culture of aerobes or facultative anaerobes but for the growth of many aerobes, it is necessary to provide extensive aeration. Forced aeration of cultures is therefore frequently desirable and can be achieved either by vigorously shaking the flask or tube on a shaker or by bubbling sterilized air into the medium. When aerobic organisms are to be grown in large quantities, it is advantageous to increase the exposure of the medium to the atmosphere. This can be accomplished by dispensing the medium in shallow layers or by providing aeration by constantly shaking the inoculated liquid cultures.

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• SciCrunch
• 4 years ago - submitted by Jon Matthews

Microorganisms exist in a mixed state in nature. To obtain the desired strains, they must be isolated. Accidental contamination during the preservation of the bacteria should also be purified. There are many methods of microbial isolation and purification, but the basic principle is similar, that is, the sample to be isolated is diluted to a certain extent, and the microbial cells (or spores) will exist in a dispersed state as far as possible, and then they will grow into a single colony of pure species. The above work is inseparable from inoculation, which is the process of transferring one microorganism to another sterilized medium. For the cultivation of specific bacteria, one or more special media suitable for the growth of specific bacteria are often used. The culture of bacteria, fungi, and actinomycetes is common, and the culture of single species can also be carried out.

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• SciCrunch
• 4 years ago - submitted by Jon Matthews

Anaerobic bacteria are widely distributed in nature, humans, and animals. Non-spore anaerobes mainly exist in human and animal bodies, especially in the intestines, oral cavity, upper respiratory tract, and urinary tract. Together with aerobic bacteria and facultative anaerobes, they form the body's normal flora. Anaerobic bacteria usually have an absolute advantage in normal flora. Under normal circumstances, the protection of the flora is relatively balanced, such as long-term use of broad-spectrum antibiotics, hormones, immunosuppressants, etc. However, the occurrence of flora imbalance or decreased body resistance can lead to endogenous anaerobic bacteria infection. The toxins produced by some anaerobic bacteria are extremely dangerous to advanced organisms including humans (such as tetanus toxin and botulinum toxin). Strain anaerobic culture refers to the culture of microorganisms in an oxygen-free environment. The techniques include the anaerobic tank method, anaerobic bag method, biological consumption method, pyrogallic acid method, and blister medium method, etc.

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• SciCrunch
• 4 years ago - submitted by Jon Matthews

Facility equipped with instruments for optical and electron microscopy, and Flow Cytometry.Offers experimental design, equipment training, staff operated image acquisition, and image analysis. All users must be trained by Facility staff to access the equipment.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Creative Biogene provides range of services and products to assist researchers in cardiac disease related mitochondria studies. Offers comprehensive testing services for evaluation of variety of cardiac diseases. Mitochondria focused testings and services with advantage of animal based models.

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• SciCrunch
• 4 years ago - submitted by Joe Cohen

Creative Biogene provides comprehensive range of services and products to assist researchers in cancer related mitochondria studies. Offers tests and services with advantage of cell based and animal based models.

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• SciCrunch
• 4 years ago - submitted by Joe Cohen

Creative Biogene works with you to validate and explore pathogenesis of mitochondria associated syndromes and possible interventions, with professional services and products to support your research. Provides rapid mitochondrial function testing services, allowing clients to accurately analyze relationship between disease and mitochondria.

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• SciCrunch
• 4 years ago - submitted by Joe Cohen