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Electrophysiology core facility that is part of Ion Channels and Transporters in Immunity Research Program.Research area includes ion channel and transporter function and ionic signaling in immune cells.Users who are studying other cell types or organ systems are welcome.Provides assistance with experimental design, training, implementation, and data analysis.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core offers optical analysis instrumentation from specialized light microscopes to bioluminescence preclinical imagers to flow cytometers for multicolor cellular analysis. Services include high resolution optical sectioning of fixed cells and tissues, time lapse imaging of living cell cultures, non invasive monitoring of tumor formation in preclinical studies, and extracting specific cells of interest from tissue samples.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Set of automated workflows for common sequencing based (Illumina) protocols, such as RNA-seq, ChIP-seq, ATAC-seq, WGBS/RRBS methylation, whole genome/exome/targeted variant detection, and contaminant screening. Sequencing data analysis pipelines.

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• SciCrunch
• 5 years ago - by Anonymous

Aesthesiometer for mechanical stimulation Model 37550. Instrument designed to automate assessment of touch sensitivity on plantar surface of rats or mice and comes ready with all necessary accessories. At each paw withdrawal, automatically detects and records latency time, and actual force at time of paw withdrawal reflex. Movable force actuator is positioned below plantar surface of animal and desired force and force speed is applied, as preset by operator. Von Frey type 0.5mm rigid filament exerts increasing force, until animal twitches its paw.

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• RRID-Legacy
• 5 years ago - submitted by Anita Bandrowski

Project to align physical sample identifiers. Used to design, develop, and promote service infrastructure to uniquely, consistently, and conveniently identify material samples, record metadata about them, and persistently link them to other samples and derived digital content, including images, data, and publications.

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• RRID-Legacy
• 5 years ago - submitted by Anita Bandrowski

Integrated platform for designing clinical trials.

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• dkNET
• 5 years ago - submitted by Maryann Martone

Software application for annotating character matrix files with ontology terms. Character states can be annotated using Entity-Quality syntax, where entity, quality, and possibly related entities are drawn from requisite ontologies. In addition, taxa (the rows of a character matrix) can be annotated with identifiers from taxonomy ontology. Phenex saves ontology annotations alongside original free text character matrix data using new NeXML format standard for evolutionary data.

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• dkNET
• 5 years ago - submitted by Maryann Martone

Platform for multilevel and longitudinal data.Provide researchers such as behavioral and social scientists with tools and education related to study design including Calculating power and sample size for any univariate or multivariate test for general linear multivariate model, assuming fixed predictors;Producing confidence intervals on power estimates for designs with fixed predictors;Producing power calculations for designs with single Gaussian covariate;Supporting designs with unequal group sizes, and complicated covariance structures;Creating basic power curves.

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• dkNET
• 5 years ago - submitted by Ko-Wei Lin

Software R package provides alternative canonical correlation,redundancy analysis function, with associated print, plot, and summary methods.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software R package for significance tests for canonical correlation analysis, including asymptotic tests and Monte Carlo method.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software R package for multivariate analysis and scale construction using factor analysis, principal component analysis, cluster analysis and reliability analysis.Procedures for Psychological, Psychometric, and Personality Research. Used for personality, psychometric theory and experimental psychology.

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• RRID-Legacy
• 5 years ago - by Anonymous

Facility provides diverse range of Mass Spectrometry based proteomics and metabolomics services.Services include sample preparation, sample analysis, and data interpretation.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core laboratory with infrastructure and expertise to perform all aspects of protein and small molecule structure determination using X-ray crystallography. For protein structure determination, high-throughput methods are utilized to move projects rapidly from gene-to-structure.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Facility provides instrumentation and training in following areas of High resolution X-ray CT,Small animal X-ray CT,Flow cytometry and sorting,Confocal microscopy,Multiphoton microscopy,Super resolution microscopy,Laser capture microdissection,Light microscopy,Spectrofluorometry,Bioluminescence imaging,High resolution ultrasound imaging,Image visualization and analysis.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Facility provides training, consulting, assisted use and independent access for wide variety of cell sorting and analysis.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Software tool fo detecting genomic breakpoints of fusion transcripts in random hexamer RNA-seq data. Used for detection of exonic, intronic and intergenic fusion transcripts and their genomic breakpoints in poly(A)+ and rRNA-minus RNA sequencing data.

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• SciCrunch
• 5 years ago - submitted by Youri Hoogstrate

Core has range of instruments for characterization and structure elucidation of chemical and biophysical samples. Our staff maintains instruments and provides data collection services as well as training and support for self use of many of our instruments. We are most equipped in areas of NMR spectroscopy, Mass spectrometry and X-ray crystallography, but we also have optical and calorimetric instruments.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core is full service histology laboratory available to faculty, researchers, clinicians and students.Provides histological services for both animal and human tissue. Services include paraffin processing and embedding, paraffin and frozen sectioning as well as routine and special histological staining.Equippemnt includes:Leica Bond III Immunostainer to provide automated immunohistochemistry, in-situ hybridization and immunofluorescence staining;Automated tissue processors for paraffin processing; Automated microtomes for paraffin sectioning; Automated stainer that can be programmed to provide wide variety of routine and special stains;Cryostats for sectioning frozen tissue; Tissue Microarray machine.LPHCF can also perform manual chromogenic or fluorescent staining (single or multi-color labelling) on frozen and paraffin sections. We also provide full service slide scanning using Axio Scan.Z1 for Brightfield or Fluorescent stained slides at either 20X or 40X magnification.Personnel in the LPHCF are available for consultation on project/protocol design, technical assistance and training on facility instruments.Infinity software system is used for all of our histological services and instrument training.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Software as cloud based community driven repository to store, share, and publish traumatic brain injury research data. Aims to increase transparency with individual level data, enhance collaboration, facilitate advanced analytics, and conform to increasing mandates by funders and publishers to make data accessible. Members of ODC-TBI have access to private digital lab space managed by PI or multi-PIs for dataset storage and sharing. PIs can share their labs’ datasets with registered members of ODC-TBI community and make their datasets public and citable. ODC-TBI implements stewardship principles that scientific data be made FAIR (Findable, Accessible, Interoperable and Reusable).

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• dkNET
• 5 years ago - submitted by Jeffrey Grethe

Software Python package.Python analysis module for AVATAR recording system. Uses three-dimentional coordinate data to produce motor coordination data from general information like velocity and total distance to behavior clustering based on python scripts.

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• RRID-Legacy
• 5 years ago - by Anonymous