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Core provides bioanalytical and pharmacokinetic support for the research groups and associated clinical trials within the institute, creating a bridge between the laboratory and clinic. Offers services performing bioanalysis using mass spectrometry, quantify therapeutic drugs as well as small molecule cancer related metabolites (targeted metabolomics), analysis of samples from matrices including plasma, blood, tissues, tumours, and cells.
Web interface provides automated variant-level classification, supporting evidence, provenance and links to biomedical literature for supported GRCh38 germline nuclear single-nucleotide variants and simple indels. Results require review by qualified genetics professionals.
Software tool for synteny block discovery, evolutionary breakpoint identification, and ancestral genome reconstruction. Used in comparative genomics and evolutionary biology, enabling deeper insights into genomic architecture and evolutionary relationships.
Core supports researchers in the use of modern light microscopy systems. Provides advanced optical imaging equipment, technical expertise, and hands-on training for biomedical and clinical research projects. Microscope platforms include confocal and multiphoton microscopy for imaging fluorescently labeled structures to enable the investigation and characterization of cells, tissues, organisms, and biomaterials with high spatial and temporal resolution.
Software R package to audit research outputs for compliance with open science best practices. Evaluates adherence to standards such as pre-registration and data availability. Used for automated checks of research outputs for best practices.
Web browser-based platform designed to work with biological sequences without needing to install specialized software or create an account. Bioinformatics toolkit for DNA, RNA and protein sequence analysis: reverse complement, translation, ORF finding, primer/oligo Tm and design, restriction sites and cloning, protein properties, codon optimisation, CRISPR guide design, and sequence alignment. Also exposes a Model Context Protocol (MCP) server and JSON REST API for programmatic and AI-agent access. No account or API key required.
Core provides support for data analysis, statistics, and software development. Offers advice on experimental design, statistical modelling, and hypothesis testing and runs training courses to assist research scientists in performing their own analyses.
Proteomics Facility is the centralized service unit of the Medical Faculty of RWTH Aachen University for the analysis of proteome samples. Offers sample preparation and mass spectrometric analysis, as well as bioinformatic processing of raw data (identification and quantification) of peptides and proteins, along with functional bioinformatic analysis of the resulting datasets.
Core provides Next Generation Sequencing (NGS) expertise and services including nucleic acid sample extraction, quantification, RT-qPCR and Quality Control (QC), experimental design, advanced data analysis.
Core facility provides genome editing services in vitro and in vivo for translational cancer research. Services span functional genomics (CRISPR screens across cells, organoids and patient-derived xenograft models, integrated with single-cell RNA sequencing), transgenics (embryo manipulation, pronuclear injection, electroporation, cryopreservation, and import/export of genetically modified models), and multimodal pre-clinical trials run through a dedicated Small Animal Hospital using genetically engineered, xenograft and orthotopic models. Offers experimental design consultation to match editing technologies to each research question.
Ocular service platform and research company launched by Topcon Healthcare. Provides researchers with ethically sourced, de-identified real-world datasets and clinical trial data for artificial intelligence (AI) and digital health innovation. Primary service is providing AI-ready datasets (such as retinal images, visual function metrics, and EMRs). Access to these databases is generally not a direct "consumer free" service; rather, researchers and sponsors must navigate a structured application and review process overseen by an independent Data Access and Governance (DAG) committee. While IDHea aggregates clinical screening data from routine optometry visits, the patient-facing eye imaging itself is usually part of standard care.
Core is multi-user and service laboratory that offers comprehensive genetic and genomic services. Provides expert consultation, grant application support, training, and both standard and customized sequencing library preparation. Collaborates on genomics, transcriptomics and epigenomics projects.
Core offers research instrumentation for hands-on use to researchers. Provides molecular biology, analytical, and imaging instruments to serve RI’s biomedical scientists totaling 3800 sq. ft. in the URI College of Pharmacy building.
System enables precise recording and stimulation of electrogenic cells across multiple wells, combining single-cell sensitivity with scalable experimental capacity. MaxTwo captures electrical activity from individual cells and complex networks with high precision, allowing scientists to detect even the smallest action potentials. This accelerates data collection and deepens insight into cellular function. Used in neuroscience and drug discovery. It features thousands of microscopic sensors embedded in culture plates that record the electrical activity (action potentials) of living cells, such as neurons and heart cells, at single-cell and subcellular resolutions.
Software R package to provide simple and uniform way of evaluating R expressions asynchronously using various resources available to the user. Unified parallel and distributed processing in R for everyone.
Software tool to combine purrr’s family of mapping functions with future’s parallel processing capabilities.
Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.
Software tool that ingests datasets from diverse knowledge bases and transforms them into modular, interoperable knowledge graphs.
Spectrophotometer to rapidly quantify and assess the purity of extremely small biological samples (like DNA, RNA, oligonucleotides, and proteins). It has a patented, maintenance-free sample port that allows you to measure sample volumes as small as 0.5 μ L to 1 μ L without needing a cuvette. In addition to the micro-volume port, it includes a standard 10 x 10 mm cuvette port. This allows for traditional spectrophotometry uses like enzyme kinetics, cell density (OD600) measurements, or assays requiring larger volumes.
Compact, filter-based laboratory instrument used to measure the optical density (absorbance) of solutions in standard 6- to 96-well microplates. It is primarily used for running ELISA assays, enzyme activity projects, and general life science research. Detection Mode: Absorbance-only (UV-Vis). Accommodates 6-, 12-, 24-, 48-, and 96-well plates (with specialized NB models supporting 384-well plates).