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Provides services and equipment for PCR and SPR experiments. The services provided include DNA sequencing and oligonucleotide synthesis.
High-performance, low-pulse, peristaltic pump with interchangeable pump heads for delivering a diverse variety of liquids—from biological to chemical—without altering the critical components within the liquid. Six different channel and flow rate configurations are available.
Technological core facility for the BMBI laboratory (Biomechanics and Bioengineering, Université de Technologie de Compiègne), which focuses on developing models and solutions to monitor and analyse physical capabilities and health status in humans and/or animals, with the aim of promoting well-being and healthy ageing.
Laboratory device used in neurophysiology to store and keep living brain tissue slices healthy before testing. Used to incubate acute brain slices for electrophysiology experiments.
Australian biomedical research institute located in Darlinghurst, Sydney, New South Wales, for ultra-high-resolution spatial proteomics and mass spectrometry imaging, examining how cancers interact with their surrounding microenvironment.
Core provides services and instruments including Bruker timsTOF fleX system that unites high-resolution spatial MALDI Mass Spectrometry Imaging with 4D-omics profiling. Powered by Trapped Ion Mobility Spectrometry (TIMS) and MALDI-2 technology, the instrument enables direct, label-free mapping of peptides, lipids and metabolites directly from tissue sections at cellular-level resolution. Provided imaging services including Peptide/protein, Lipids, Small molecule metabolites, Glycans are available to researchers across Australia.
Microscope system used to optically image, characterize, and map nanoscale materials and biological structures without needing chemical or fluorescent tags. Captures a full light spectrum (from visible near-infrared to short-wave infrared) at every single pixel of an image. Developed for spectral characterization and spectral mapping of nanoscale samples imaged with the patented CytoViva darkfield-based microscope.
Software Pennsieve analysis workflow application to create dbGaP submission files.
Nanoflow liquid chromatography (nanoLC / nano UHPLC) system that pairs with Bruker mass spectrometers to separate complex protein and peptide samples before analysis. It handles ultra-low, sub-picogram sample sizes with high sensitivity. A special needle wash system cuts cross-sample contamination by up to three times. TwinScape software monitors pressure, flow rates, and system stability while running background diagnostics. It connects directly with Bruker's TIMS-enabled mass spectrometers via HyStar software.
Mass spectrometer upgrade powered by the Athena Ion Processor (AIP) designed for ultra-sensitive 4D-proteomics and deep cellular analysis. Boosts signal intensity and provides a 2x to 3x improvement in sensitivity. Uses trapped ion mobility spectrometry to separate noise from actual signals at high speeds (up to 300 Hz). Lets researchers target specific mass ranges or open up broad ranges for specialized glycoproteomics.
Software batch effect adjustment tool for bulk RNA-seq count data.
Software R toolkit for accurate and efficient estimation of cell composition ('decomposition') from bulk expression data with single-cell information. Used to estimate cell-type proportions in bulk RNA sequencing data by robustly integrating single-cell RNA-seq (scRNA-seq) or single-nucleus RNA-seq (snRNA-seq) information.
Automated high-throughput microscopy platform used to automatically capture and analyze images of cells, tissues, and whole organisms across multi-well plates and microscope slides. Features a high-sensitivity sCMOS camera and fast frame-rate technology capable of processing over 200,000 wells per day at lower magnifications. Supports widefield fluorescence, brightfield, phase contrast, and colorimetric imaging, with options for spinning-disk confocal. Utilizes MetaXpress Software for automated image acquisition, 3D analysis, and predefined or custom cellular assay modules.
Software pipeline to evaluate and validate the accuracy of variant calling methods in genomic research. The workflow provides benchmarking tools for small variants including SNVs and INDELs, Structural Variants (SVs) and Copy Number Variations (CNVs) for germline and somatic analysis.
Core provides NMR services and instrumentation including 500MHz NMR spectrometers and X-band EPR spectrometer.
Core provides service for one-stop spatial biology solutions from sample handling to high-end spatial data generation. Serves as a specialized bridge between laboratory research and clinical application (immuno-patho translation). Offers services in general histology, spatial transcriptomics and spatial proteomics. It primarily focuses on experiment designing, optimisation, spatial proteomic staining and imaging, allowing assay customisation, development and validation.
Core provides expertise in Next Generation Sequencing (NGS) technologies to provide users with full spectrum of genomic services, including microarray analysis (ie genotyping and methylation arrays), NGS library preparation, short-read and long-read sequencing, genotyping.
GLP-certified animal pathology laboratory house within A*STAR iCORE provides research facilitation to A*STAR Research Institutes, Universities, Health sectors, Major pharmaceutical companies, and SMEs in Singapour. Staffed by highly experienced professionals and supported by robust infrastructures, the laboratory delivers valuable pathological insights that contribute to research projects, grant applications, and scientific publications across diverse disciplines. The laboratory was previously known as Advanced Molecular Pathology Laboratory (AMPL).
Provides flow cytometry analysis and expert‑assisted cell sorting to accelerate discovery across basic, translational, and clinical research. Users may independently access advanced flow cytometry analyzers, while all cell sorting services are performed by highly trained specialist operators to ensure optimal purity, viability, and data quality. Our diverse fleet of conventional and spectral instruments supports deep immunophenotyping, small‑particle detection, and cell sorting for both mammalian and non‑mammalian systems.
iCORE Proteomics, previously known as Advanced Proteomics Platform (A~PROMPT) provides proteomics service for research in Singapore. Services include instrumentation use, Protein ID, Whole proteome ID, Targeted proteomics, Labelled free quantitation proteomics (LFQ), TMT proteomics, Post-Translational Modifications proteomics (phospho/Ubi PTM), Clinical proteomics, DIA-proteomics.