Curator Dashboard

Core is component of Integrated Genomics Core/High Throughput Sequencing Facility. Supports population, basic, clinical and translational research by providing centralized cost efficient, high quality genotyping and methylation services using Illumina BeadArray and Infinium microarray assay technologies for Single Nucleotide Polymorphism Genotyping, Copy Number Variant, Loss of Heterozygosity, Insertions Deletion (indel), Structural Variant, and DNA Methylation Analysis. Can assist with selecting appropriate arrays to meet your needs.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software toolbox containing many kinds of kits that you may be interested in during fMRI data analysis. This toolbox is a homebrew kits built during practical ASL(arterial spin labeling) based Cerebral Blood Flow (CBF) data analysis. Meanwhile, this toolbox is also compatible with BOLD data analysis. Everyone would find something useful for their own data analysis! This toolbox is run and tested on SPM8 with MATLAB 7.6.0(R2008a) under the Linux OS. Theoretically, most of the functions (except the menu1&2 which are specially designed for the Batch Editor of SPM8) of this toolbox should be compatible with SPM5 and should also work smoothly under the Windows OS. Feel free to give feedback to authors if you encounter any bugs or problems. Senhua Zhu Center for functional Neuroimaging, University of Pennsylvania 3 W.Gates Bldg, 3400, Philadelphia, PA (19104), United States Email: [email protected] ; [email protected] QQ group number (QQ?): 60524357 Google group: https://groups.google.com/d/forum/fmri-grocer

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• SciCrunch
• 14 years ago - by Anonymous

Core services including ensurance that purified proteins and other biomolecules of interest are uncompromised in terms of their structure and stability. Facilitates analyses of catalytic activities and functional interactions.Examines thermodynamic and kinetic parameters for association between proteins and small molecules.Facilitates hypothesis generation through coalescence of experimental data and computational modeling.Assists in setting up protein crystallization assays.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Repository of biospecimen and phenotype data collected from Crohn's disease and ulcerative colitis cases and controls recruited at six sites throughout North America that are available to the scientific community. Phenotyping is performed using a standardized protocol, and lymphoblastoid cell lines are established for each subject. Phenotype data for each subject are collected by the Consortium's Data Coordinating Center (DCC), and phenotype data for all subjects with DNA samples are available. The resulting DNA samples have already been utilized by the Consortium to complete various association studies, including genome-wide association studies using dense genotyping arrays. Researchers can obtain DNA samples and phenotype, genotype, and pedigree data through the Data Repository. GWAS data must be requested through dbGAP. The IBDGC is involved with independent genetic research studies and actively works with members of the IBD and genetic communities on collaborative projects. They are also members of the International IBD Genetics Consortium. Phenotype Tools: The Consortium Phenotype Committee, led by Dr. Hillary Steinhart designed and validated paper forms to collect extensive phenotype data on Crohn's Disease and ulcerative colitis. Consortium phenotype tools are available for use by non-Consortium members.

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• SciCrunch
• 14 years ago - by Anonymous

Web tool for interactive visualization and analysis of diversity of genomic variants. Used for interactive exploration and analysis of very large SNP matrices based on VCF files.

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• RRID
• 4 years ago - by Anonymous

Provides vocabulary for performing several types of annotation - comment, entities annotation (or semantic tags), textual annotation (classic tags), notes, examples, erratum... - on any kind of electronic document (text, images, audio, tables...) and document parts. AO is not providing any domain ontology but it is fostering the reuse of the existing ones for not breaking the principle of scalability of the Semantic Web.

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• SciCrunch
• 17 years ago - by Anonymous

Software R package for bindings to liblwgeom library.

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• SciCrunch
• 4 years ago - by Anonymous

An ontology covering the domain of social entities that are related to health care, such as demographic information (social entities for recording gender (but not sex) and marital status, for example) and the roles of various individuals and organizations (patient, hospital, etc.)

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• SciCrunch
• 13 years ago - by Anonymous

Software R package with convenience functions for analyzing factorial experiments using ANOVA or mixed models.

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• RRID
• 4 years ago - by Anonymous

Public bibliographic database that provides access to citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. PubMed citations and abstracts include fields of biomedicine and health, covering portions of life sciences, behavioral sciences, chemical sciences, and bioengineering. Provides access to additional relevant web sites and links to other NCBI molecular biology resources. Publishers of journals can submit their citations to NCBI and then provide access to full-text of articles at journal web sites using LinkOut.

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• SciCrunch
• 17 years ago - by Anonymous

Connects industry members with Penn State research community of artificial intelligence and machine learning researchers and their students to solve real world problems and seize market opportunities.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Encyclopedia of DNA elements consisting of list of functional elements in human genome, including elements that act at protein and RNA levels, and regulatory elements that control cells and circumstances in which gene is active. Enables scientific and medical communities to interpret role of human genome in biology and disease. Provides identification of common cell types to facilitate integrative analysis and new experimental technologies based on high-throughput sequencing. Genome Browser containing ENCODE and Epigenomics Roadmap data. Data are available for entire human genome.

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• SciCrunch
• 17 years ago - by Anonymous

Core aims to facilitate research in cognitive neuroscience through use of Computerized Neurocognitive Battery and neuroimaging.CNB is comprised of series of tests that have been applied in neuroimaging studies and can be used either in scanner as part of functional neuroimaging study or outside scanner for measuring individual differences in performance. Tests measure accuracy and speed of performance in major domains of cognition, including executive control functions (abstraction, attention, working memory), episodic memory (verbal, facial, spatial), complex cognitive processing (language reasoning, nonverbal reasoning, spatial processing), social cognition (emotion identification, emotion intensity differentiation, age differentiation) and sensorimotor and motor speed.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core does routine paraffin and frozen sectioning on tissues for research purposes. We offer consultation services, and fee-for-service tissue grossing, processing, embedding, sectioning and staining. Special stains are also done routinely. Paraffin-embedded or frozen sections can be passed-on to a partner core, the BIDMC-Confocal and Immunostaining core, for DAB or fluorescence staining and analysis. No training or independent usage of Histology core or its equipment is possible.

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• SciCrunch
• 13 years ago - by Anonymous

Offers access to instrumentation, training, and service using advanced light microscopy, scanning electron microscopy, and transmission electron microscopy. Provides access to core imaging and analytical characterization technologies. In addition to instrument access, SRNML personnel offer advice, hands-on training, education, and research collaboration. Provides range of sample preparation equipment.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Flow cytometry analysis service, Cell cycle analysis, Cell sorting service, Side population cell sorting, Zebrafish cell sorting and analysis. The Stem Cell Core Facility has been part of the IDDRC center for more than 30 years fostering collaboration and innovation among IDDRC investigators and members of the academic research community. It was used to develop chromosome sorting for human chromosome specific recombinant libraries and these techniques were utilized by others to generate large scale libraries for the early genome project. The facility was the first to develop cell sorting of fetal cells in the maternal circulation as a means to detect fetal genetic abnormalities. Throughout its history the Stem Cell Core has provided careful and accurate cell cycle analysis via DNA content analysis using Hoechst dye uptake. This service is still used today by investigators. The facility was among the first to take advantage of the ability to express GFP in cells transfected with vectors and induced to express GFP in transgenic animals conditionally expressing a specific gene promoter. This ability allowed IDDRC investigators to isolate neurons, muscle cells and other cell types which express GFP from those which do not. IDDRC investigators were among the first to subsequently culture sorted neurons. Based on the extensive experience of the core using Hoechst dye for cell cycle analysis, the core was able to help IDDRC investigators prepare side population cells (tissue derived potential multipotent progenitor cells) based on Hoechst dye efflux. These methods have allowed the isolation of different muscle side population cells and have facilitated experiments that aim to use the cells for treating muscle disease. The interactive and collaborative nature of the core has fostered these developments, and the interests of the core director, advisory committee, manager and IDDRC investigators will continue to make this core as innovative in the future as it has been in the past. The overall goal of the Stem Cell Core Facility is to provide both IDDRC and non-IDDRC researchers comprehensive analytical flow cytometry and cell sorting services in a timely, dependable and cost-effective manner., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 13 years ago - by Anonymous

Services include use of high throughput screening technology, compounds in various libraries, siRNA sets of druggable genome for mouse and human and database of results from screens. For compounds screens, data points are in singlets.For functional genomics screens we use duplicates. We typically utilize 384 well plates but are flexible in this regard. We can accomodate any plate type ranging from 96 to 1536 well plates. Specialty plates can be handled on needed base. We have special rates for consumables with many vendors based on volume we use. These reduced rates are passed on directly to our screeners.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Data collection, data entry and analysis, Database design, data management and process tracking, Qualitative data collection, management and analysis.

The Survey and Data Management Core (SDMC) provides efficient, high-quality survey data collection and management services and consultation to support the research needs of investigators and staff throughout the Harvard Medical research community. The Core, housed within the Center for Population Sciences at the Dana-Farber Cancer Institute, is dedicated to rigorous quantitative and qualitative survey data collection and management.

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• SciCrunch
• 13 years ago - by Anonymous

Sotware R package for differential discovery analyses in high dimensional cytometry data including flow cytometry, mass cytometry or CyTOF, and oligonucleotide tagged cytometry.

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• RRID
• 4 years ago - by Anonymous

Core facility that provides the following services: Cell sorting service, Cell analyzing service, Cell separation service, Cell cytometer service, Data services, Flow cytometry protocol development service, Benchtop flow cytometry analyzer training, Flow cytometry beta-testing service. Committed to meet all of the flow cytometry needs for the BIDMC and the external research community, the Flow Cytometry Core facility offers state of the art instrumentation for routine flow cytometry and cell sorting. It is continuously expanding with the newest software and machinery for both sort and analysis capabilities of up to 30 flourescent parameters. The Flow Cytometry Core facility is available to: answer technical questions; assist you in setting up flow cytometry experiments; assist you with acquiring, analyzing and interpreting your data; assist in data presentation and data storage; provide training on the four benchtop analyzers and on software. To schedule an appointment for regular flow cytometry (user operated), log onto our online web calendar at: http://bidflow.calendarhost.com/

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• SciCrunch
• 13 years ago - by Anonymous