Curator Dashboard

Software tool to reverse-engineer transcriptional regulatory networks from co-expressed gene sets by identifying master transcription factors (TFs) and their direct target genes. It operates by scanning for enriched TF binding motifs in promoter regions, utilizing over 10,000 position weight matrices (PWMs) for human, mouse, and Drosophila. Used to enable gene regulatory network mapping directly based on motif enrichment in co-expressed gene set.

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• 4 months ago - by Anonymous

Core supports fundamental, translational, and clinical research by providing advanced services and expertise in cytometry, photonic microscopy, mass imaging, in vivo imaging, and bioinformatics. The cytometry and mass imaging unit offers flow, spectral and mass cytometry, cell sorting, multiplex panel development, and high‑dimensional data analysis. Photonic microscopy unit provides comprehensive support from sample preparation to image processing, with access to widefield, confocal, multiphoton and super‑resolution systems, and benefits from national recognition through IBISA and France BioImaging labels. The platform also hosts clinical transfer imaging activities (SP2I), developing optical tools for surgery and pathology in close collaboration with clinicians, with numerous funded projects and industrial partnerships. Request for citation from this core facility is to use the full name (synonym in this record) and address of the core: "Université Paris-Saclay, Gustave Roussy, INSERM, Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse, F-94805 Villejuif, France, Plateforme d'Imagerie et Cytometrie PFIC (RRID:SCR_028222)"

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• 4 months ago - submitted by Tudor Manoliu

Gustave Roussy is Europe’s leading comprehensive cancer center, located in Villejuif near Paris, France. It is a premier institution dedicated entirely to cancer treatment, research, and teaching, often ranked among the top oncology hospitals worldwide. Founded in 1925, it specializes in personalized medicine, rare cancers, and complex tumors.

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• 4 months ago - submitted by Edyta Vieth

Tokyo Chemical Industry Co., Ltd. (TCI) is a leading global manufacturer of specialty organic chemicals, founded in 1946. They produce over 30,000 research chemicals, including laboratory chemicals, reagents, and functional materials. TCI also acts as a supplier, offering custom synthesis and bulk production from milligrams to tons.

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• 4 months ago - by Anonymous

Image acquisition system to capture of chemiluminescence and fluorescence images. Using cooled CCD technology in combination with motorised optical lens, Fusion FX7 offers very high sensitivity and extended dynamic range. Data produced are directly compatible with image analysis software developed by VILBER and 1D image can be transformed into 3D results with Bio-1D and the Bio-Gene software.

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• 4 months ago - by Anonymous

Neuroanatomy-anchored Information Management Platform for collaborative BICAN data generation developed by UTHealth Houston. Serves as metadata tracking engine to support generation, management, and sharing of brain research data. Integrates data production pipelines across brain banks, laboratories, sequencing centers, and data archives. Platform enables integrative and collaborative, consortium-scale FAIR data generation within the BICAN project. Platform is designed to manage complex dataset, including tissue samples and sequencing data, through Specimen Portal and Sequence Library Portal. Portals provide multiple types of data interfaces through dashboards, APIs, faceted queries, and batch data ingestion and exporting.

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• 4 months ago - submitted by Guo-Qiang Zhang

Web tool to search life science articles with AI you can verify and control. Life science search engine designed to hit the sweet spot between classical search and AI-assisted research.

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• 4 months ago - submitted by Iskander Charfi

Core offers tools to precisely modify the genome of cells and organisms using CRISPR-Cas9-based editing, CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa) systems. Our platforms enable high-throughput genetic screening, gene knockouts, transcriptional modulation, and sequence editing with high efficiency and scalability.

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• 4 months ago - submitted by Edyta Vieth

Core provides infrastructure and analytic support for population-based cancer research at UPMC Hillman Cancer Center. PANDA helps investigators access, manage, link, and analyze population-based cancer datasets to study cancer surveillance, treatment access, and survival in western Pennsylvania and across the United States using datasets such as SEER-Medicare, the Pennsylvania Cancer Registry (PACR), Pennsylvania Health Care Cost Containment Council (PHC4) hospital discharge data, the National Cancer Database (NCDB), and the UPMC Network Cancer Registry, along with area-level and geospatial data relevant to the Hillman catchment area.PANDA provides consultation on study design and data selection, assistance with data management and linkage, analytic dataset creation, population-level and geospatial analyses, and support for manuscripts and grant applications.

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• 4 months ago - submitted by Edyta Vieth

Premier Canadian academic medical research center located in Toronto, affiliated with the University of Toronto and Sunnybrook Health Sciences Centre focusing on translating scientific discoveries into clinical practice, with specialties in medical imaging, biology, and clinical trials.

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• 4 months ago - submitted by Edyta Vieth

Core offers services including cell sorting,cell analysis, user training for the flow cytometer benchtop analyzers, user training for the widefield and confocal microscopes.

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• 4 months ago - by Anonymous

Filmetrics F20 is a versatile, benchtop thin-film measurement system designed to measure the thickness, refractive index, and extinction coefficient of thin films. Using spectral reflectance in less than a second, it measures single or multi-layer stacks.

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• 4 months ago - submitted by Texas State CRO

Advanced, stylus-based surface profiler used for high-precision, 2D and 3D surface topography measurements, including step height, surface roughness, and waviness. System measures roughness in the nanometer range. It provides a step-height repeatability of 5Å. It uses a diamond-tip stylus to physically trace samples, offering sub-nanometer vertical resolution and high repeatability.

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• 4 months ago - submitted by Texas State CRO

A high-speed confocal microscope for 3D imaging of live or fixed biological samples, offering multi-wavelength laser excitation and high-resolution imaging capabilities.

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• 4 months ago - submitted by Texas State CRO

A high-resolution TEM providing imaging, diffraction, and spectroscopic analysis at the atomic scale, suitable for materials science and nanotechnology applications.

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• 4 months ago - submitted by Texas State CRO

An inverted optical microscope designed for high-resolution live-cell imaging, fluorescence microscopy, and advanced multi-channel experiments in cell biology and materials research.

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• 4 months ago - submitted by Texas State CRO

Facility EVG 501 wafer bonder system applies pressure up to 10kN and temperature up to 450C to samples with prepared surfaces (specific chemical surface termination). When the system mechanically brings these surfaces into contact the temperature and pressure sequence activates chemical bonds at the interfaces that fuse the sample surfaces together. A precision wafer bonding system used to join semiconductor wafers using thermal, adhesive, or anodic bonding techniques for device integration.

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• 4 months ago - submitted by Texas State CRO

A thermal processing system used to introduce p-type dopants into semiconductor substrates through controlled diffusion at elevated temperatures.

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• 4 months ago - submitted by Texas State CRO

A high-temperature furnace is used to introduce n-type dopants into semiconductor wafers through controlled diffusion processes.

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• 4 months ago - submitted by Texas State CRO

Fcility AGA Heatpulse 610 is a benchtop rapid thermal annealer (RTA/RTP) that utilizes high power lamps to heat treat thin films and substrates for processes such as contact formation, silicide formation, and dopant diffusion/activation. Temperature control via PID loop has a maximum heating rate of ~50 C/s and maximum temperature of 1000 C. The chamber can also be atmospheric purged with N2, Ar, 4% H2balAr, or O2. A rapid thermal processing system that enables fast heating and cooling cycles for semiconductor wafers, used for dopant activation, oxidation, and material modification.

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• 4 months ago - submitted by Texas State CRO