We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Cancer Sciences Flow Cytometry Facility is a joint facility between the School of Cancer Sciences at the University of Glasgow and the CRUK Scotland Institute. Provides access to flow cytometry instrumentation and support from technical experts in analysis and cell sorting.
Web based tool as advanced version of GEPIA that provides comprehensive analysis of gene/protein interactions across various cancer types. This version facilitates the investigation of treatment sensitivity utilizing both real-world patient data and cell line screens for over 1000 therapeutic agents, as well as the integration of RNA alterations derived from the pan-cancer analysis of whole genomes project. GEPIA3 represents a significant enhancement of the original platform, enabling in-depth exploration of gene regulation and cancer phenotypes, thereby supporting the identification of novel biomarkers and therapeutic targets.
Source analysis and data processing code for article titled "Single-Cell Multi-Omics Insights into BMI-Mediated Immune-Related Disease Risk".
A commercial adeno-associated virus (AAV) vector driving the expression of the inhibitory DREADD hM4D(Gi) fused with an mCherry reporter under the control of the CaMKIIa promoter. Used for targeted chemogenetic inhibition. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) vector driving the expression of the excitatory DREADD hM3D(Gq) fused with an mCherry reporter under the control of the CaMKIIa promoter. Used for targeted chemogenetic activation. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) control vector driving the expression of the mCherry fluorescent reporter under the control of the CaMKIIa promoter, specifically targeting glutamatergic neurons. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) vector driving the expression of a genetically encoded fluorescent serotonin (5-HT) sensor under the control of the pan-neuronal hSyn promoter for in vivo neurochemical monitoring. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) vector containing a double-floxed inverted orientation (DIO) cassette for Cre-dependent expression of the red-shifted optogenetic activator ChrimsonR and an mCherry reporter under the pan-neuronal hSyn promoter. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) vector driving the expression of Cre recombinase under the control of the CaMKIIa promoter, enabling targeted recombination in glutamatergic neurons. Provided by BrainVTA.
A commercial adeno-associated virus (AAV) vector containing a double-floxed inverted orientation (DIO) cassette for Cre-dependent expression of the excitatory DREADD hM3D(Gq) and mCherry reporter under the EF1a promoter. Provided by BrainVTA.
Web-based tool for analysis of sets through Venn diagrams. Allows set unions in Venn diagrams to be explored thoroughly, by consequence extending the ability to analyze combinations of sets with additional observations, yielded by novel interactions between joined sets.
Stand-alone open-source software with graphical user interface for analysis of time-lapse microscopy images. Combines bio-image analysis and mathematical modeling for study of DNA repair dynamics.
Core promotes conduct of high-quality qualitative research with focus on integrating key stakeholder perspectives into research designs. It helps investigators with study design, funding proposals, data collection, and analysis to understand contextual, sociocultural, and experiential factors in health.
Tissue bank and full service histology core. Provides support for tissue banks staining imaging and spatial applications.
The Roy J. Carver Center for Genomics (CCG) is a research and service center within the Department of Biology on the campus of the University of Iowa (UI). The CCG maintains a centralized laboratory with equipment and instruments available for investigators to use in their molecular research.
Core offers light microscopy and imaging services. Provides access to and training on various confocal microscopes.
Software nuclei instance segmentation and classification framework based on hybrid task cascade.
National Cancer Institute (NCI)-sponsored randomized, controlled study (1993–2001) of ~155,000 adults aged 55-74 to evaluated whether organized, regular screenings could reduce cancer deaths compared to usual care. Portal provides randomized, controlled trial data used to determine whether certain screening exams reduce mortality from prostate, lung, colorectal and ovarian cancer.
Open-source foundation model for histology. Vision transformer model trained on haematoxylin and eosin stained tissue whole slide histology images. AI foundation model for pathology, developed by French startup Bioptimus. Launched as one of the largest open-source models for digital pathology, it is trained on histopathology slides for tasks like tissue classification, mutation prediction, and cancer subtyping.
Software tool for processing Epi-Proteomics mass spectrometry data. Discriminates isobaric histone peptides using distinguishing fragment ions in their tandem mass spectra and extracts the chromatographic area under the curve using previous knowledge about peptide retention time. Nanoflow liquid chromatography coupled with high resolution tandem mass spectrometry-based quantification tool for histone peptides, which can also be adapted to analyze nonhistone protein samples. EpiProfile 2.0 is extended version of v1.0 for enhanced quantification of histone peptides based on LC-MS/MS analysis.