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Software tool for 3D tracking and automatic classification of rodent behavior. Used for acquisition, annotation, and automatic behavioral profile characterization of laboratory rodents' RGB-D videos. Utilizes video segmentation, tracking of body parts, and automated classification of behaviors through machine learning and computer vision methods. Setup uses low costing RGB-D cameras for tracking behaviors in various environments. Software includes GUI interfaces for video acquisition, annotation, and processing of behavioral data. Software is capable of automated behavior detection with only 30 minutes of annotated video.
Software Python toolkit developed at Allen Institute for Cell Science for 3D segmentation of intracellular structures in fluorescence microscope images. Used for segmenting 3D intracellular structures in fluorescence microscopy images.
To facilitate cross-dataset comparison, the Allen Institute created the Common Cell type Nomenclature (CCN) for matching and tracking cell types across studies that is qualitatively similar to gene transcript management across different genome builds. The CCN can be readily applied to new or established taxonomies through a set of user-friendly R scripts, and has been applied to diverse cell type datasets derived from multiple quantifiable modalities. The CCN facilitates assigning accurate yet flexible cell type names in the mammalian cortex as a step toward community-wide efforts to organize multi-source, data-driven information related to cell type taxonomies from any organism.
A lab that validates antibodies.
Web-based design tool for CRISPR base editing. Guide RNA designer for CRISPR base editing. Provides all possible base editor target sequences in given input DNA sequence with useful information including potential off target sites.
Software R package for mapping country data.Enables mapping of country level and gridded user datasets by facilitating joining to modern world maps and offering visualisation options. Country borders are derived from Natural Earth data v 1.4.0.
Software R package as set of standards that specify common storage and access model of geographic features made of mostly two dimensional geometries used by geographic information systems. Standardized way to encode spatial vector data. Formalized by Open Geospatial Consortium and International Organization for Standardization.
Core to capture mass spectral data obtained through time-of-flight measurements that can be used for 3D nanoscale compositional analysis to identify light mass and heavy mass species with equivalent sensitivity.
Software command line Python package for computation of chokepoint reactions in genome scale metabolic models. Used to compute chokepoints by taking into account both topology and dynamic information of network. Can compute and remove dead-end metabolites, find essential reactions and update flux bounds of reactions according to results of Flux Variability Analysis.
Web application that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Enables searching for potential off-target sites in any sequenced genome rapidly without limiting PAM sequence or number of mismatched bases.
Web-based design tool for CRISPR base editing. Guide RNA designer for CRISPR base editing. Provides all possible base editor target sequences in given input DNA sequence with useful information including potential off target sites.
Provides medical care, in vivo research support, and disease surveillance to laboratory animals at Stanford University . Our board certified and board eligible veterinarians offer consultation in appropriate animal modeling, animal care techniques, experimental methodology, anesthetic techniques, surgical techniques, pain management, humane euthanasia techniques, and animal use (APLAC) protocol consultation. AALAS certified veterinary technicians are available to provide technical support including dosing, biosampling, conducting anesthesia and post-operative care, for example.
Procures and provides needed tissue specimens to Stanford Cancer Institute investigators to support cancer related research. Services include collecting and banking freshly frozen tumor and normal tissue from surgical material and autopsy specimens;Providing fresh tumor tissue for viable cell studies;Processing and banking blood from cancer patients;Maintaining tissue database with links to clinicopathological data;Providing histological staining and pathological review;Coordinating patient consent and assuring regulatory compliance.Provides portal to virtual bank which links inventories of specialized satellite repositories, including collections of hematological and neurosurgical specimens.
Collecting and banking freshly frozen tumor and normal tissue from surgical material and autopsy specimens.Provides fresh tumor tissue for viable cell studies,processes and banks blood from cancer patients,maintains tissue database with links to clinicopathological data,providing histological staining and pathological review,coordinating patient consent and assuring regulatory compliance.
Core manager provides oversight and training on user-friendly instrumentation so that each investigator is able to perform sorts and analysis on their own.Manager also provides technical help with more complex sorts, ensures that instruments are maintained properly, and will perform troubleshooting as necessary. This novel design will allow for critical stem cell sorts to be done efficiently and economically.
Offers clinical laboratory services including hematology, cytology, serum chemistry, electrolyte analysis, coagulation profiles, fluid analysis, serology/immunology, parasitology, and microbiology; Specializes in diagnostic and research needs of laboratory animals. Committed to improving diagnostics, developing additional reference ranges for various clinical pathology parameters in laboratory animals, and supporting health surveillance and disease management.
Academic service center specializing in planning, installation and maintenance of research computer systems.
Services include genome editing of mice, rats and cell lines, mouse line cryopreservation and re-derivation, ES cell targeting, PDX models, drug screening.Crispr Mediated KO/KI and Conditional KO Mice,KI mouse by mouse ES cell genome editing,Integrase Mediated Transgenesis,Conventional Transgenic Mouse,Mouse Line Services,Cell Line Services. Tumor Model Services include In vivo tumor models,In vivo pharmacology,In vitro and biochemical assays,Translational imaging services.
Provides access to ultrasound, MRI, CT, and PET, instruments developed specifically for small animal work and photoacoustic imaging. All instruments are designed to image living subjects and allow for repeated imaging. The flexibility and rapid analyses of such animal models greatly accelerate the development of molecular imaging strategies.Facility houses surgical procedure room, histology slide scanner that converts glass slides into digital slides using both brightfield and fluorescence, and advanced image analysis workstations.Instruments include MicroPET Imaging Systems,Optical Imaging Systems,UltraSound Imaging System,Photoacoustic Imaging System,X-Ray Computed Tomography Imaging System,Magnetic Resonance Imaging.