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Nonprofit organization with mission to advance molecular sciences by building open source software and sustainable communities for research software development. Focuses on working with hosted projects to support their software development and provide operational support, while also pursuing own community-service and community-building projects. Uses fiscal sponsorship as business model available to nonprofit organizations to assemble resources, provide support and advance open source projects in molecular sciences aligned with charitable purpose and general public interest.
Web based collaborative text annotation tool. Used for managing multi-user, multi-label document annotation. Project managers can specify annotation schema for entities and relations and select annotators and distribute documents anonymously to prevent bias. Document input format can be plain text, PDF or BioC (uploaded locally or automatically retrieved from PubMed/PMC), and output format is BioC with inline annotations. Displays figures from full text.
Data integration and dissemination project for carbohydrate and glycoconjugate related data. Computational and informatics resources for glycoscience. Portal provides user-friendly interface that facilitates exploration of glycoscience data from diverse international bioinformatics resources, including National Center for Biotechnology Information (NCBI), UniProt, Protein Data Bank (PDB), UniCarbKB, and GlyTouCan glycan structure repository. Retrieves information from data sources and integrates and harmonizes this data. Includes knowledge about molecular, biophysical and functional properties of glycans, genes, proteins and lipids organized in pathways and ontologies, plus data related to mutation and expression.
ROBOKOP system consists of web based user interface, API server, and several worker servers. Biomedical knowledge graph that integrates and semantically harmonizes important knowledge sources. Contains nodes representing entities such as genes, chemicals, and diseases, and edges representing relationships between them. Abstraction layer and user interface for knowledge graphs to support question answering. Used for reasoning over structured biomedical knowledge databases as part of NCATS translator and reasoner programs. ROBOKOP Knowledge Graph Builder constructs KG and provides extensible framework to handle graph query over and integration of federated data sources.
Medical wiki of interventions, regimens, and general information relevant to fields of hematology and oncology. Knowledge base for hematology and oncology providers, containing details about hematology/oncology drugs and treatment regimens. Any healthcare professional can sign up to contribute. Acuracy and completeness of content is overseen by Editorial Board.
Consortium to improve health outcomes and reduce HIV transmission among diverse range of populations affected by alcohol and HIV infection in Florida. Fosters interdisciplinary translational research, training and community engagement. One of five national Consortia for HIV/AIDS and Alcohol Research Translation (CHAART). Supports Researcher Hub for researchers interested in SHARC research, publication, presentations, and opportunity to access, and analyze datasets via SHARC Concepts System.
Web application for multi-level multi-cluster selections in dendrogram. Provides interactive visualization of dendrogram in which users can divide dendrogram at any level and into any number of clusters.
Offers to run high-throughput compound, RNAi, and deletion library based screens for purpose of network analysis, drug and/or target discovery. Offers assistance to develop assay, carryout screen and/or analyze data. Equipment is also available for general (low-throughput) use. Helps with developing custom pipeline. Biomek FX liquid handling workstation with integrated Liconic shaker incubator (temperature, humidity, and CO2 controlled) can be used to setup and grow most cell types in 96 well plates. This robot is equipped to add RNAi constructs, drugs or other stimuli to each plate. Biomek FX can also be used to perform high-throughput biochemical assays. Cell based assays can be carried out using either Operetta CLS high-content analysis system or CLARIOstar plus. Both instruments have powerful, but easy to use software for data analysis.
Flow cytometry facility provides instrumentation for data acquisition, analysis, and cell sorting, technical expertise to interpret results and develop methods. Offers information about new techniques, and applications of flow cytometry through workshops and seminars, and provides training to interested facility users. Individual consultation services are available.Human Immune Monitoring Facility provides immune profiling, sample preparation,clinical trial support, technical expertise to clinical investigators and research scientists.Services include multispectral flow cytometry, metabolic analysis, blood services such as PBMC isolation and serum/plasma extraction, and full spectrum of immunological services.Offers custom assays and biobanking services upon request.Offers training, assisted, unassisted, and technician operated modalities for all instruments and will meet investigators at their desired level of engagement.
Provides imaging small animals and samples with variety of modalities depending on needs including MRI, X-Ray CT, PET, SPECT, luminescence, and fluorescence. Works closely with Radiochemistry Core Lab which can synthesize custom, targeted PET and SPECT imaging agents.Offers preclinical imaging tools designed for imaging rodents.
Software repository for mtDNA assembly project.
Software tool to find shared repeats between mitochondrial genomes.
Automated cell counter with software algorithm to provide accurate counting results for variety of cell types by automatically declustering clumped cells, performing size and roundness based sorting, and identifying live and dead cells. Can confirm cell counts prior to experimental data acquisition, quality check, passaging, or induction of differentiation.
Phython script for bootstraping Treemix snp trees to generate confidance intervals in the main tree.
Software neuroscience laboratory environment for simultaneous neuronal imaging and behavioral monitoring. McGill-Mouse-Miniscope Touchscreen Behavior Platform. Standardized approach for high throughput imaging of neuronal dynamics during behavior.
Software package contains tools for analyzing data from NanoString GeoMx Digital Spatial Profiler. Provides functions to read, quality control and normalize starting from Nanostring DCC and PKC files generated from NanoString GeoMx DSP. Contains definition of NanoStringGeoMxSet class which inherits from Biobase’s ExpressionSet class and NanoStringRCCSet class.
Web tool to analyze survival data by single year of diagnosis and estimates changes in survival trends and year over year trend measures.
Provides broad spectrum of resources designed to make techniques of genomics, functional genomics, and recombinant DNA technology. Services include Next Generation sequencing, single cell analysis, spatial transcriptomics, Sanger Sequencing, qPCR, digital PCR, Nanostring, and microarray analysis.
Fasteris, the brand of Genesupport SA for all Life Science Services, provides Next Generation Sequencing and Sanger sequencing services.Offers customized approaches and consulting services at each step of your projects.