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The Korean Genome and Epidemiology Study (KoGES) is a large prospective cohort study aimed at investigating the genetic and environmental risk factors of major chronic diseases in Korea. As of November 2017, epidemiological data of more than 23 million participants are available for researchers. Researchers who want to access the KoGES data may do so via the online data sharing service available at http://cdc.go.kr/CDC/ or http://nih.go.kr/NIH_NEW. After submitting institutional review board approval documentation, research proposal and a list of requested variables, researchers can download the data within 7 days. In addition, researchers who want to use genomic data and/or biospecimens, together with epidemiological data may do so via the one stop portal services of Korea Biobank Network (KBN) available at http:// koreabiobank.re.kr The Korean Genome Epidemiology Study (KoGES) is a principal cohort study providing valuable evidence for the prevention of major chronic diseases such as hypertension, obesity, and diabetes in Korea Cohort Profile: The Korean Genome and Epidemiology Study (KoGES). Consortium https://doi.org/10.1093/ije/dyv316 waiting for the submitter insufficinet information Cohort Profile: The Korean Genome and Epidemiology Study (KoGES) Consortium
Interactive web server to explore and analyze single cell RNA-seq data. R shiny based tool used for single cell RNA-seq data visualization and analysis.
Software Python library for hierarchical clustering. Fast Hierarchical, Agglomerative Clustering Routines for R and Python.
Provides access to advanced light and electron microscopes as well as imaging expertise. Applications range from material science to biomedical research. Provides custom image analysis, comprehensive sample preparation for light and electron microscopy, and consultation.
Software tool for redesign and expansion of prediction on kinase specific phosphorylation sites. Machine learning based kinase specific phosphorylation site prediction tool.
Software tool for speeding up estimation of phylogenetic trees for large alignments through parallelization and vectorization strategies.
Software package as collection of WDL workflows to build linkage maps from sequencing reads. WDL workflows to build genetic maps from sequencing reads.
Software parallel Big Data toolkit to process FASTA and FASTQ files at scale. Used to manipulate FASTA/Q files at scale with speed and scalability at its core.
Web tool for predicting DNA methylation sites. Identifies methylation sites for three different types of DNA methylation, namely N6-adenine, N4-cytosine, and 5-hydroxymethylcytosine. MuLan-Methyl-Multiple transformer based language models for accurate DNA methylation prediction.
Provides access to in vivo imaging technologies including molecular imaging, optical imaging, quantitative physiologic and anatomic imaging, and whole body PET/CT scanning in humans and animals. Provides targeted imaging probes and tracers as well as expertise in planning, executing and analyzing in vivo imaging studies. Supports imaging studies in small animals, large animals and humans.This resource is located in three adjacent buildings in the Health Sciences district of the Davis campus:Center for Molecular and Genomic Imaging (CMGI), Genome and Biomedical Sciences Facility (small-animal imaging);Nuclear Magnetic Resonance (NMR) Facility, Tupper Hall (small-animal MRI);Center for Imaging Sciences (CIS), Veterinary School (large-animal imaging).
Provides services to support the development and implementation of clinical trials at UC Davis Comprehensive Cancer Center. Oversees high quality collection, processing, and analysis of clinical specimens,typically but not exclusively blood specimens, for pharmacokinetic and pharmacodynamics studies. Conducts preclinical modeling of novel anti cancer agents to test hypotheses and develop scientific rationale required for translation of laboratory concepts into clinical trials, including assessment of DM/PK/PD properties.
Clinical Laboratory Improvement Amendments certified laboratory established to provide scientific support to investigators conducting clinical studies in humans, preclinical studies in animals and/or studies in veterinary medicine. Conducts immunology based assays needed to monitor patients in clinical immunotherapy trials. Offers molecular and cellular assays for investigators in different fields, including custom assays designes.
Provides expertise and comprehensive services to accomplish virtually every application of next generation sequencing based genomics research, including gene expression profiling, mutation/variant analyses, copy number analysis, epigenomics, metagenomics, single cell sequencing and spatial transcriptomics services. GSR also specializes in development of custom protocols and extensive data analysis and integrative bioinformatics support. The shared resource provides wide range of additional services for translational and clinical genomics research.
Provides expertise in design, analysis and reporting of cancer related studies, including basic, translational, clinical and population based research. BSR affiliated faculty and staff work with investigators from the earliest stages of study planning. The shared resource is especially committed to mentoring early career cancer researchers.
Provides high throughput screening platform to discover unique chemical probes against biological targets using various one bead one compound and one bead two compound combinatorial libraries.Interacts closely with resource users on optimization of the lead compounds via focused libraries and standard medicinal chemistry techniques. Provides custom synthesis of telodendrimer based micellar nanoparticle platform for efficient drug delivery.
Provides specimens with annotated data for clinical and basic science research purposes.Biorepository functions as centralized tissue bank to provide researchers access to cancer- and non-cancer-related specimens including fresh or frozen tissue, paraffin blocks,sections and fluids, procured and stored using international standards of best practices and protocols compliant with Office for Human Research Protection. Specimens can be obtained prospectively as part of clinical trials or accessed through UC Davis Health Clinical Laboratories, where over 5.5 million blood specimens are processed annually.
Department of Chemistry houses comprehensive array of research facilities to support diversity of scientific work. Staff members expertly maintain each facility and are available to help users set up experiments or interpret results. Our resources facilitate scientific progress from giving chemists deeper understanding of their data to providing essential characterization of compounds for publication.
Cytiva is the new name of the former GE Healthcare Life Sciences biopharma business following its acquisition by Danaher Corporation, according to an April 1, 2020 announcement. Provider of life sciences brands such as ÄKTA, Amersham, HyClone, MabSelect and Whatman.