We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Collection of transcription factors annotated according to experimental and other evidence on their function as true DbTFs. Provides reference for both small scale experiments and genome scale studies. Curated compendium of specific DNA-binding RNA polymerase II transcription factors.
Core provides resources to investigate phenotypes of genetically altered mice and small animal models of disease. Offers investigators full service support of in vivo cardiovascular and physiology studies in normal and diseased states through surgical models, imaging techniques, and functional physiological assessments.Core provides services to assist researchers with phenotyping of small laboratory animals including mice, rats, guinea pigs, rabbits with focus on cardiovascular neuromuscular and respiratory function, and exercise tolerance. Services include Experiments with cardiovascular ultrasound, plethysmography, exercise studies, small animal surgeries LAD-ligation, transaortic constriction, and data analysis; Training with equipment, small animal surgeries or data analysis; Equipment rent to measure cardiovascular, neuromuscular, respiratory function, and exercise tolerance;Consultation on experimental design, physiological data-collection, analysis, interpretation and IACUC protocols, grant- and manuscript writing.
Prospective, observational, longitudinal, study designed to characterize landscape of genomic cancer signals in blood of people with and without cancer. Sudy includes people in the USA and Canada who had cancer at the time of enrollment, newly diagnosed, and not yet received treatment, and people who did not have known cancer diagnosis.
Web application for data visualization and analysis to explore brain tumors expression datasets.Used to help researchers and clinicians to rapidly access data relevant to brain tumor research.
Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.
Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.
Method extending ’guilt by association’ principle to literature information by using Bayesian framework to suggest diseases associated with overlooked metabolites.
Software R package for converting and retrieving information of miRNAs in different miRBase versions. Used for converting and retrieving miRNA Name, Accession, Sequence, Version, History and Family information in different miRBase versions. Can process huge number of miRNAs in short time without other depends.
Software tool bridges in vitro drug screening with in vivo drug and biomarker discovery. Predicts in vivo or cancer patient drug response and biomarkers to enrich for response from cell line screening data. Builds model using ridge regression, and enables biomarker discovery by imputing drug response in large cancer molecular datasets. Enables drug specific biomarker identification by correcting for general level of drug sensitivity shared among the population.
Software connectivity mapping based drug repurposing tool that identifies drugs that can potentially reverse query disease phenotype or have similar functions with query drugs.
Web tool for transcriptome wide microRNA target prediction including lncRNAs.Used for whole transcriptome human microRNA target predictions based on the comprehensive GENCODE gene annotation, including long non-coding RNA genes. Coding genes are also covered, including atypical regions such as 5'UTRs and CDS. MicroRNA family definitions and names are consistent with TargetScan. Site conservation is aluated based on 46 vertebrates species.Map of putative microRNA target sites in the long non-coding transcriptome.
Software R package for unified access to computational methods for estimating immune cell fractions from bulk RNA sequencing data.
Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.
Core was established to provide infrastructure to support Research Project Leaders and principle investigators associated with the Dr. Richard J. Bellucci Translational Hearing Center to conduct auditory and vestibular research across the full range of experimental model systems, from single molecule analysis to whole organism models. We also offer access to our services and instruments to outside users.
Software platform for modelling and simulation of agricultural systems. Contains suite of modules that enable simulation of systems for diverse range of plant, animal, soil, climate and management interactions. Used to simulate biophysical processes in agricultural systems, particularly as it relates to the economic and ecological outcomes of management practices in the face of climate risk.
Core for conducting metabolomics studies on variety of biofluids and tissue extracts from plant and animal sources. Provided instruments include Agilent 5975C series GC-MSD, Bruker NEO 600 NMR, Thermo Exactive Plus, Thermo Orbitrap Exploris 120, Thermo Orbitrap Exploris 240, Thermo TSQ Quantis Plus, Thermo Orbitrap Fusion Lumos Tribrid.
Deputy cabinet level agency directly under the State Council of China. Responsible for collection, investigation, research and publication of statistics concerning the nation's economy, population and other aspects of the society.
Software package implements Bayesian multilevel models in R using probabilistic programming language Stan.
The Codes for the Administrative Divisions of China define 6-digit codes for each of the administrative regions from the province level down to the county level.