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Core is comprehensive data and biospecimen bank (malignant and normal tissue and their derivatives, blood and bone marrow) for research along with a range of services that accompany biospecimens. Facilitates access to human tissue, blood and bone marrow for investigators with Institutional Review Board (IRB) approved protocols emphasizing translational research. Helps investigators to establish Biospecimen and Data Research (BDR) protocols and supports the submission of grants by providing feasibility analysis, cost estimates and letters of support.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core helps research scientists and imaging core facilities produce, handle, safeguard, and share high-quality bioimage data. Ensures compliance with standards for image data management and sharing. Helps to plan experiments, track experimental conditions, and produce data.BioImage DMS eases the burden of data publication and sharing when the project is published.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Genomics core is a self-supporting core facility specializing in Sanger sequencing, SNP/fragment analysis, and Next Generation DNA Sequencing using Illumina's MiSeq platform. Provides sequencing services.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides clean rooms, cell therapy equipment, manufacturing know-how, capabilities and comprehensive suite of quality assurance and control procedures.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides consultations and services for investigators and study teams in the areas of clinical research, informatics, and data science. BRISR helps researchers harness internal and external data resources and provide informatics-driven solutions for clinical and translational research. Offers the infrastructure and processes to establish and monitor data standards, quality integration and distribution, educational and training opportunities. Provide services in three main areas: (1) Clinical data management and delivery for research, (2) Custom software development for research, and (3) Artificial intelligence analysis for clinical and bioinformatics research.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides bioinformatics assistance for design, analysis and interpretation of genomics, proteomics and other studies for better understanding of cancer biology, thereby facilitating translation of cancer omics discoveries to cancer treatment. Provides services in design of experiments, raw omics data processing, data analysis and interpretation, data mining and integration, informatics infrastructure for data sharing and management, review and prepare grants and manuscripts, software evaluation, new method and database development,bioinformatics education and training for investigators.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides MUSC Hollings Cancer Center members with sophisticated equipment, technologies, training, and expertise required for successful, cell and tissue-based microscopic imaging and image analysis.Optical Microscopy Services include equipment and expertise to facilitate imaging of tissues and cells by Hollings members. Innovative Techniques service include development and application of new imaging techniques to meet the emerging scientific needs of Hollings members.Education and Training services include education, trainning, and consultation on imaging technologies that enable scientific discovery, including a biennial Charleston Workshop on Light Microscopy for the Biomedical Sciences, as well as a lecture series on cell and molecular imaging, especially as it relates to tumor biology.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers services including expert technical staff performing all aspects of sample preparation, QC, assay design and analysis. Provides integrated set of tools and services for genomic analysis. Expertise and services include clone generation, high throughput mapping, array technology development. Offers genomics platforms including data analysis, training and education on instruments and methodologies, complete discovery/screening to validation services, and full Laboratory Information Management System (LIMS) request, workflow and sample management.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides highly sensitive measurements for an extensive array of chemotherapeutic agents and metabolites to support basic research and preclinical/clinical drug development.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Software R package extension of ggplot2 designed to create information rich plots that include details from statistical tests directly within the visual output. Used to enhance {ggplot2} plots with statistical analysis.

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• RRID
• 3 months ago - submitted by Patricia Rojas

Software tool for rules for DICOM tag based labelling. Regular expression used during the SCANDAN project to label MRI scans based on DICOM tag.

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• RRID
• 3 months ago - submitted by Dorian Gouzou

Label-free live-cell imaging system designed for high-content screening. Label free live cell imaging microscope allows to instantly observe and analyze the inside of living cells in 3D without using toxic stains, leveraging AI-powered digital assays and holographic tomography to automate workflows and provide fast, high-resolution data.

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• RRID
• 3 months ago - by Anonymous

Core provides researchers with access to Cryo Electron Microscopes and related tools for high resolution structural biology imaging experiments.

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• RRID
• 3 months ago - submitted by Paul Tobias

High-throughput, 32-spot Surface Plasmon Resonance (SPR) system. The "Pro" designation commonly used by Bruker highlights its capabilities, including 8 flow cells with 4 spots each, designed for rapid, label-free molecular interaction analysis. Used for the Real-Time, Label-Free characterization of molecular interactions.

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• RRID
• 3 months ago - by Anonymous

High resolution UV-Visible spectrophotometer with double-beam, single monochromator, variable spectral bandwidth and a photomultiplier tube (PMT) detector. Used for measuring absorbance, transmittance, and reflectance of liquid or solid samples across the UV-visible range 190-900nm. Used for quantitative analysis (concentration measurement) and spectral characterization.

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• RRID
• 3 months ago - by Anonymous

Customizable polarimeter used to measure the optical rotation of chiral compounds. It identifies, analyzes, and determines the purity and concentration of liquids (specifically optically active samples) in pharmaceutical, chemical, and food manufacturing industries, featuring customizable light sources for UV-Vis to NIR regions.

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• RRID
• 3 months ago - by Anonymous

Bruker Invenio S is an entry-level FT-IR spectrometer designed for routine productivity and basic research and development. Analytical instrument that identifies chemical compounds and molecular structures by measuring how samples absorb infrared light. Offers upgradable Invenio platform featuring the Transit channel and MultiTect technology.

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• RRID
• 3 months ago - by Anonymous

Provides advanced resources in structural biology. Offers access to instruments, including multiple transmission electron microscopes (TEMs) and cryo-FIB/SEM systems. Trains scientists, from beginners to experienced users, on sample preparation (plunge/high-pressure freezers) and advanced EM techniques. Helps researchers solve the 3D structures of proteins and cellular components at atomic resolution.

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• RRID
• 3 months ago - submitted by Edward Eng

Core provides advanced NMR spectroscopy for researching the atomic-level structure, dynamics, and interactions of biological macromolecules. It supports structural biology, biocatalysis, and drug discovery by analyzing proteins, DNA, RNA, and carbohydrates. Includes 800MHz NMR spectrometer with H/F-C-N Cryoprobe.

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• RRID
• 3 months ago - submitted by Matthew Cliff