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Facility dedicated to preclinical and clinical research in brain imaging in the field of mental health to foster development of new biomarkers for early diagnosis, treatment and prevention of neuropsychiatric conditions. Instruments include human (3T MRI Siemens Prisma Fit) and animal (7T Bruker Biospec) imaging equipment. Expert staff provides support for project design, acquisition and analysis. Core offers project specific conceptual assistance, 3D printing and prototyping in addition to facilities for equipment production (coil design and production). Team consists of traditional and computational neuroscientists, basic and clinical researchers, image analysts, magnetic resonance imaging physicists, and expert technologists
Core provides access to characterization and process instrumentation. Expert staff provides assistance and guidance. Services include electron microscopy and analysis (SEM, TEM, FIB, EBSD, WDS), microelectronic device fabrication (7000 sq ft cleanroom, Class 100-1000), X-ray computed tomography (CT), particle system characterization (size, zeta potential, surface area, porosity, rheology), X-ray diffraction, surface analysis (AFM, profilometry, XPS, Auger), spectroscopy (UV/Vis with integrating sphere, FTIR/NIR with micro capability and micro-Raman).
Facility utilizes LabMA system developed by Luminex Co., for protein analysis that permits simultaneous quantitative analysis of up to 100 different proteins, peptides, or RNA molecules in single microtiter well. Commercially available assays from Millipore, R&D Systems, Bio-Rad or Thermofisher are also used for analysis.
Advanced imaging core for multi channel fluorescence imaging,3D imaging, super resolution imaging, scanning, image analysis in cancer research. Technical services are forcused on fluorescent in situ hybridization, immunohistochemistry, and microdissection of biological material.
Core for image based analysis, laser capture microdissection, and live cell fluorescence imaging. Provides range of consultation and laboratory services performed by core staff. Users training is available.Cell and Tissue imaging on confocal microscopes including Zeiss LSM 710, Leical Sp8 and Leica Stellaris.
Spatial biology company, building multiplex immunofluorescence and IHC solutions for discovery and immuno-oncology research.Laboratory equipment supplier in Tolochenaz, Switzerland.
Caliper provides products and services for life sciences research. The firm, founded in 1995, is based in Hopkinton, Massachusetts with direct sales, service and application support operations in countries around the globe.
Company designs, develops and commercializes molecular pathology systems for tumor diagnosis, prognosis, precision medicine and life science research.
Web tool to detect under- or over-dispersion in a baseline table from baseline table.
Facility maintains large array of instrumentation for production and analysis of complex materials, including nanoparticles, thin films, polymers, ceramics, and molecular electronics.Oversees operations of Department Biological Instrumentation Cluster which provides access to specialized equipment used in molecular biology and biological chemistry.
Facility specializes in training users in both solution phase and solid state NMR across all active nuclei and multiple NMR experients
X-Ray Diffraction Facility located in Chemistry Instrumentation Center is equipped with Bruker X8 Prospector Ultra with Copper ImuS micro-focus X-ray source and Bruker D8 Venture Dual source (Molybdenum and Copper micro-focus X-ray tubes) diffractometer with Photon III CPAD detector. Data can be collected at nitrogen-cooled temperatures as low as 90K. Core provides sample submission services for small molecule crystalography.
Core supports fabrication and characterization of nanoscale materials and structures, and integration of devices at all length scales. Houses advanced equipment with core nano-level capability for fabrication and characterization, including electron-beam lithography system, dual-beam system, plasma etching, thin film deposition, TEM, multifunctional scanning probe station, modular XRD, and more.
Core provides mass spectrometry instruments including Bruker Daltonics UltrafleXtreme MALDI TOF-TOF, Shimadzu Instrument LCMS-2020,Shimadzu Instrument QP2010S GCMS,Thermo Fisher Oribtrap Exploris 240,Thermo Scientific Q-Exactive Oribtrap for determining masses of particles, and elemental composition of sample or molecule.
Collection of in situ hybridization data of gene expression in the brain of adult fish. Data can be viewed and downloaded.
Web Java application for visualizing and analyzing trends and patterns in scientific literature. Provides various functions to facilitate understanding and interpretation of network patterns and historical patterns,finding citation hotspots, decomposing network into clusters, automatic labeling clusters with terms from citing articles, geospatial patterns of collaboration, and unique areas of international collaboration. Supports structural and temporal analyses of networks derived from scientific publications, including collaboration networks, author co-citation networks, and document co-citation networks. Supports networks of hybrid node types such as terms, institutions, and countries, and hybrid link types such as co-citation, co-occurrence, and directed citing links.
Software tool for extracting low-allele-frequency tumor mutations from sequencing background noise in clinical practice. Detects variations, specifically low allele frequency variation, in next generation sequencing data.
Web based database to search human and mouse housekeeping and candidate reference genes/transcripts. It also offers tissue and cell selective candidate reference transcripts and some primers for quantitative PCR normalization.
Software suite of business analytics tools to connect to all sorts of data and create visuals and reports. Interactive data visualization and reporting platform developed by Microsoft. Part of Microsoft Power Platform.
Software library and tool for accessing remote BLOW5 files. Used for fetching reads from remote BLOW5 files.