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Dutch National supercomputer system facilitates scientific research carried out in many Universities, independent research institutes, governmental organizations, and private companies in the Netherlands. Cluster of heterogeneous nodes built by Lenovo, containing predominantly AMD technology, with capabilities for high performance computing (parallel, symmetric multiprocessing), data-processing, and machine learning. Has several system specific storage resources, that are geared towards supporting the various types of computing. System has peak performance of 14 petaflop/s, making it the most powerful high-performance computing system in the Netherlands.
Software library providing Python interfaces to proteomic data. Provides set of modules to facilitate the most common tasks in proteomics data analysis.
Web application for metaproteome data analysis, with initial focus on tryptic-peptide-based biodiversity analysis of MS/MS samples.Designed for metaproteomics data analysis with focus on interactive data visualizations. Unipept 4.0 introduces complementary functional analysis based on GO terms and EC numbers.
Software R package for simultaneous exploration of multiple datasets. Compositional omics model based visual integration.Used to integrate omics data for visualization, with special focus on compositionality.
Software tool as classifier that utilizes k-mer composition of assembled sequences to identify eukaryotic genome fragments prior to gene prediction. Used for eukaryotic sequence identification. Classification of Eukaryotic and Prokaryotic sequences from metagenomic datasets.
This national resource was created to provide neuroscience community with access to reagents, training and facilities that are necessary to use neurotropic viruses as transneuronal tracers.
Portal for Hybrid Rat Diversity Program with goal to extend the use of rat models for clinical translation through establishing animal resource and genomic dataset to facilitate the translation of laboratory research to clinical relevance. Specifically, the Hybrid Rat Diversity Panel resource provides the research community with foundation for systems genetics and tool for forward genetics.
Project portal for generating recombinant NWM proteins, producing mouse monoclonal antibodies against New World Monkeys, validating immunological assays using these reagents, and distributing reagents and related scientific information to interested investigators.
Core provides Next-Generation DNA and RNA sequencing services and technical expertise including NGS library prep, DNA and RNA quality assessment, Fluorometric quantification of DNA/RNA/Protein, DNA and RNA isolation, PCR/qPCR, Qubit fluorometry, gene expression and drug development studies. Consultative services are available.
Core houses thermal analysis suite. Researchers are able to investigate behavior of material under stress and temperature change. Service level work and technical expertise are provided.
Core provides JEOL 400 MHz NMR equipped with auto sampling and automatic tuning and matching. Instrument can perform temperature and kinetic studies as well as x-nuclei and 2D experiments.
Facility enables to discover molecular, genetic, and small molecule compounds suitable to study functions of poorly understood proteins, signaling pathways, and cells in complex biological processes relevant to human physiology and disease; provides technical assistance with viral vector preparation and expression and purification of recombinant proteins; fosters collaborations. Staff will also develop and implement new technology as needed. Education and training is also available. Provides opportunities to develop new innovative basic and translational research, preliminary data for hypothesis driven research grant applications, and public-private partnerships.
Scripts to download genomes from the NCBI FTP servers.
Biobank for collecting biological samples from both ill and healthy animals. Samples are processed and cataloged with the appropriate clinical information. Biobank has ISO 20387 accreditation.
Algorithm for prediction of granules formation in yeast.
Web server for prediction of prion-like domains recruitment to stress granules upon heat stress.
Web and command-line application to identify proteins with prion-like amino acid composition. Searches protein sequences to identify probable prion subsequences using hidden-Markov model algorithm.
Web meta-server for visualization and annotation of low complexity regions in proteins. Used for discovering LCRs and provides functional annotations such as domain detection, transmembrane segment prediction, and calculation of amino acid frequencies.
Database of disordered protein predictions. Community resource for pre-computed disorder predictions on a large library of proteins from completely-sequenced genomes.
Comprehensive, semi-manually curated crowdsourcing database of biomolecular condensates and their constituents as well as encyclopedia for scientific terms used to describe them.