Curator Dashboard

Software tool to support translation of basic research in medical image analysis into early clinical studies.

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• 2 years ago - by Anonymous

Provides specialized resources and expertise to support scientists that want to incorporate systemic measures of mouse activity, metabolism and feeding. The systems are also embedded within light regulated environments to capture circadian, time of day, based outcomes.Supports scientists wanting to perform circadian type analyses with either pre-clinical or clinical time series data. Supports scientists wanting to incorporate -Omics measures into their studies with experience in genomics, proteomics and metabolomics assays/analyses. These services are available to support new investigators, early-stage investigators and current investigators in aging.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core for understanding Earth surface processes in bedrock, soil, water, and sediment. Interactions between cosmic rays and Earth’s upper atmosphere create unique isotopes both in the atmosphere and in materials on Earth’s surface. By assessing the ratios and/or concentrations of these isotopes, we can get a deeper insight into the exposure age, soil production rate, catchment-averaged erosion, and processes of Earth’s varied landscapes.

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• 2 years ago - submitted by Edyta Vieth

Software image analysis tool for digital pathology and spatial biology researchers.

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• 2 years ago - submitted by Edyta Vieth

Core facility houses the capability to test water using multiple instruments and techniques including : Ion Chromatography, which is an analytical technique for determining the concentration of anions in aqueous solutions such as fluoride, chloride, nitrate, phosphate and sulfate; Carbon and nitrogen analysis, which incorporates measurements of total carbon, total inorganic carbon and total organic carbon together with total nitrogen; and other parameters such as pH, alkalinity, turbidity, conductivity (and others) using instrumentation and kits.

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• 2 years ago - submitted by Anne Steputis

Magnetic resonance imaging research facility located at University of Colorado Boulder.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Offers services from sample preparation to image processing.Provides instrumentation for use such as electron microscopy, light microscopy, and access to other instrumentation for use in sample prep.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Integrated core offers services in Irradiation, pre-clinical imaging of small and large animals, light and electron microscopy, large and small animal cancer models. Irradiation Section assists investigators in radiation treatment planning and delivery of ionizing irradiation to cells, rodents and large animals with engineered, transplanted or spontaneous tumors.Imaging Section provides technologies for non-invasive, whole-animal imaging of animals used in preclinical research studies. Microscopy Section provides access to point scanning confocal microscopy with Airyscan super resolution, conventional bright field and fluorescence light microscopy, high throughput live imaging, automated slide scanning and image analysis resources. Electron microscopy resource provides scanning transmission electron microscopy. Animal Cancer Models section supports generation and utilization of large and small animals for modeling cancer and other human diseases. Section has expertise in generating cancer models using wild type or genetically engineered animals in immunocompetent and immunocompromised backgrounds, as well as mice with humanized immune system.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Facility provides imaging instrumentation and analysis software along with training and expertise.Instrumentation and technologies available to users include Zeiss LSM800 AIRYSCAN confocal microscope integrated with Zen software; PerkinElmer / Akoya Vectra 3.0 Automated Quantitative Pathology Imaging System;Agilent/BioTek Cytation 5 with BioSpa8 live-cell microscopy system for fluorescence and phase contrast microscopy; Olympus IX-83 ZDC2 microscope equipped with PRIMO UV light-based bioengineering device for micropatterning and microfabrication; Olympus IX73 Inverted Fluorescence Microscope.Image analysis software hosted on appropriately powered workstations with cloud connectivity for high capacity storage: HALO3, Inform, Volocity, AutoDeblur, Image-J / Fiji.Transmission and scanning electron microscopy including FEI Talos F200i (200kV TEM and STEM electron microscope (TEM), equipped for micro-analysis, and cryo-EM;FEI Helios CX5 dual beam FIB-SEM system with X-ray microanalysis detectors; instruments for specimen preparation for transmission and scanning electron microscopy including ultramicrotomes Leica Ultracut UC6 and UC7, critical point dryer Samdri-970, Leica ACE 600 coater and ThermoFisher Vitrobot.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides College of Medicine research community with access to atomic force microscopy equipment and expertise.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Genotype Sparse Compression (GSC) is an advanced tool for lossless compression of VCF files, designed to efficiently store and manage VCF files in a compressed format. It accepts VCF/BCF files as input and utilizes advanced compression techniques to significantly reduce storage requirements while ensuring fast query capabilities. In our study, we successfully compressed the VCF files from the 1000 Genomes Project (1000Gpip3), consisting of 2504 samples and 80 million variants, from an uncompressed VCF file of 803.70GB to approximately 1GB.

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• SciCrunch
• 2 years ago - submitted by Xiaolong Luo

Genotype Sparse Compression (GSC) is an advanced tool for lossless compression of VCF files, designed to efficiently store and manage VCF files in a compressed format. It accepts VCF/BCF files as input and utilizes advanced compression techniques to significantly reduce storage requirements while ensuring fast query capabilities. In our study, we successfully compressed the VCF files from the 1000 Genomes Project (1000Gpip3), consisting of 2504 samples and 80 million variants, from an uncompressed VCF file of 803.70GB to approximately 1GB.

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• SciCrunch
• 2 years ago - submitted by Xiaolong Luo

Genotype Sparse Compression (GSC) is an advanced tool for lossless compression of VCF files, designed to efficiently store and manage VCF files in a compressed format. It accepts VCF/BCF files as input and utilizes advanced compression techniques to significantly reduce storage requirements while ensuring fast query capabilities. In our study, we successfully compressed the VCF files from the 1000 Genomes Project (1000Gpip3), consisting of 2504 samples and 80 million variants, from an uncompressed VCF file of 803.70GB to approximately 1GB.

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• SciCrunch
• 2 years ago - submitted by Xiaolong Luo

Software tool for lossless compression of VCF files, designed to efficiently store and manage VCF files in compressed format. It accepts VCF/BCF files as input and utilizes advanced compression techniques to significantly reduce storage requirements while ensuring fast query capabilities.

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• SciCrunch
• 2 years ago - submitted by Xiaolong Luo

Fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. System with acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-stacks in scan mode to generate publication quality images and data.

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• 2 years ago - by Anonymous

High sensitivity flow cytometry for nanoparticle analysis for life science, nanoscience and nanotechnology studies. Can be used for multiparameter characterization of natural and synthetic nanoparticles (7-1000 nm) at the single particle level.Combining light scattering and fluorescence detection, high-resolution distributions of particle size and biochemical properties can be acquired simultaneously in 1-2 minutes. UNL Flow Cytometry Core NanoAnalyzer is equipped with two lasers (488 and 640nm), and is capable of detecting SSC and two colors. Operates under NF Professional Software. System is designed to measure size and concentration of nanoparticle samples.

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• 2 years ago - submitted by Dirk Anderson

Offers multiple configurations with the option to easily upgrade. Instrument can be configured to use up to four lasers and up to 15-color detection to identify subtle differences between cells. Core Facility’s CytoFLEX SRT is four-laser platform (405, 488, 561 and 638nm) instrument capable of detecting FSC, SSC and 15-colors and is able to sort up to four separate populations from the same sample, and deposit them in variety of tubes and plates. Operates under CytExpert SRT Software.

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• 2 years ago - submitted by Dirk Anderson

This model is equipped with four lasers (405, 488 561 and 638nm), and is capable of detecting FSC, SSC and 16 colors.

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• 2 years ago - submitted by Dirk Anderson

Software tool for analysis of non-covalent interactions in molecular dynamics trajectories. Implemented in Python and is universally applicable to any kind of MD trajectory supported by MDAnalysis package.

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• 2 years ago - by Anonymous

PCR thermal cycler with 96 well block (12 8 x 0.2 mL strip tubes, 96 x 0.2 mL), AC/DC input 230 V AC.

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• RRID
• 2 years ago - by Anonymous