Curator Dashboard

Portal for identifying genetic and pharmacologic dependencies and biomarkers that predicts them by providing access to datasets, visualizations, and analysis tools that are being used by Cancer Dependency Map Project at Broad Institute. Project to systematically identify genes and small molecule dependencies and to determine markers that predict sensitivity. All data generated by DepMap Project are available to public under CC BY 4.0 license on quarterly basis and pre-publication.

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• RRID-Legacy
• 7 years ago - by Anonymous

Core offers automation and screening capabilities. Equipped with environmentally-controlled high-content microscopes, automated liquid handlers, plate washers and readers, and robotic platforms, HTS aims to accelerate experiments from small-scale assays to large screening campaigns.

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• RRID
• 1 year ago - submitted by Mushriq Al-Jazrawe

The Inflammatory Breast Cancer Research Foundation is a non-profit corporation dedicated to the support of research and public awareness. It is dedicated to researching the cause of Inflammatory Breast Cancer, also known as IBC, an advanced and accelerated form of breast cancer usually not detected by mammograms or ultrasounds. Inflammatory breast cancer requires immediate aggressive treatment with chemotherapy prior to surgery and is treated differently than more common types of breast cancer. Our mission is to assist scientists and researchers in their quest to determine the definitive causes of inflammatory breast cancer. The Inflammatory Breast Cancer Research Foundation seeks to assist them in their work so effective and meaningful detection and diagnosis, prevention and treatment can be pursued and achieved. Our Goals Include: * To ignite interest in the study and research of inflammatory breast cancer at every level. From researchers to physicians, educators and scientists, the IBC Research Foundation seeks to support and inspire those seeking to identify the cause(s) of inflammatory breast cancer. * To support research, the purpose of which is to reach an unambiguous definition of inflammatory breast cancer. The clinical/pathological definition in use since the late 1800s with little change in the 1900s is ambiguous and doesn''t result in a diagnosis of all cases of IBC. By using research methods available in the 21st Century, an unambiguous definition is now possible, assuring with high certainty that all cases of IBC will be correctly diagnosed, and possible sub-types of IBC identified, which may lead to better treatment outcomes. * To increase awareness of IBC for primary care physicians, nursing professionals, and medical technicians in order to minimize the time from presentation of symptoms to correct diagnosis of inflammatory breast cancer. * To increase public awareness in an effort to encourage women to seek medical attention for common inflammatory breast cancer symptoms soon after they appear and to empower patients, caregivers, families and friends to pursue meaningful paths in support of diagnosis and treatment of inflammatory breast cancer.

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• SciCrunch
• 16 years ago - by Anonymous

Advanced Genomic Technologies Cluster provides next-generation sequencing and Sanger sequencing. Next-generation sequencing services are provided using Illumina MiSeq and NextSeq sequencers. Services are available for amplicon re-sequencing, viral or microbial whole genome sequencing and 16S microbiome sequencing. Sanger DNA Sequencing can be performed on DNA templates such as PCR products and plasmids using ABI 3730xl and ABI3130xl instruments.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Offers wide range of electron microscopy (both transmission and scanning), accessory instrumentation, and expertise to the scientific and engineering community through education, collaboration, and service. Provides facilities for preparation and examination of many types of bulk and thin specimens (foils/films), fine particles, and replicas, including biological materials, by transmission and scanning electron microscopy.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Public reference database supporting the XML family of markup language standards, XML vocabularies, and related structured information standards. It promotes and enables the use of open, interoperable, standards-based solutions which protect digital information and enhance the quality of data processing. The Cover Pages web site provides reference material on enabling technologies compatible with SGML/XML descriptive markup language standards and applications: object modeling, semantic nets, ontologies, authority lists, document production systems, and conceptual modeling. It also supplies references for social aspects of distributed and public sector concerns: privacy, open standards, patented technology embedded in standards, etc. NB. This statement and the resource itself are works in progress, subject to continuous revision.

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• SciCrunch
• 16 years ago - by Anonymous

Core performs and analyzes integrated clinical genomic, molecular, microarray, FISH, and cytogenetic analyses to diagnose broad range of inherited diseases and cancer. Serves as centralized clinical testing laboratory for Children Oncology Group leukemia, Wilms tumor, medulloblastoma, and rhabdomyosarcoma studies. Emphasizes collaborative interactions between clinicians, physician-scientists, and basic science investigators to quickly transition cutting edge research results into cutting edge diagnostics, using technology platforms. Services include Whole Exome Sequencing (WES),cytogenetic chromosome analysis,Fluorescence in situ Hybridization,Chromosomal microarray analysis,Molecular Genetic Testing - Inherited Diseases,Molecular Genetic Testing - Cancer.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core supports research requiring flow cytometry techniques in basic and translational research. Provides access to equipment, and technical and scientific expertise for comprehensive analysis of immune responses. Uses standardized and optimized SOPs and study protocols to obtain reproducible and quality results for our collaborating investigators in cost-effective manner.

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• RRID
• 1 year ago - by Anonymous

The Wikiversity School of Medicine is a free online educational resource for the study of medicine. It is a member of the Faculty of Life Sciences and aims to maximize collaboration with other schools within the faculty and elsewhere. Prospective students may study medicine at Wikiversity by registering with the site and joining the school. Students may study via the proposed curriculum pathway, by picking and choosing modules or lessons from the different departments or by joining the school in creating lessons. The school''s medical course is currently divided into pre-clinical and clinical sets of modules. Access to these modules is via the school curriculum. This resource is available in other languages including Deutsch, Espa��ol, Fran��ais, Italiano, Portugu��s, and .

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• SciCrunch
• 16 years ago - by Anonymous

Core provides MRI capabilities for imaging human subjects and potentially large animals as part of research studies. Facility operates GE Discovery MR750 3T whole-body scanner and can provide access to 1.5T system. Scanner is FDA cleared for clinical use. It has proprietary software including pulse programming environments and reconstruction programs and customizable software and protocols for applications including functional and structural brain imaging, abdominal perfusion and diffusion, muscle functional imaging and spectroscopy are available to users.Support for fMRI acquisition and visual and auditory stimulus presentation, diffusion tensor imaging, spectroscopy, and high quality anatomic imaging is available. The system has specialized receiver coils for sensitive imaging of particular anatomy. Additional customized coils can be manufactured in our RF lab. The system also has full broadband capability for multinuclear MRI and MRS, including (F-19, C-13, P-31, and Na-23).Our facility can also provide Image Post-processing and computerized image transfer, assistance to ensure MRI equipment safety, and can facilitate Clinical Readings.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

International reference guide for medicinal products maintained by the Uppsala Monitoring Centre. With its unique drug code hierarchy and extensive coverage, it provides consistent drug dictionary with exact terminology when coding concomitant medications. Dictionary is used to identify drug names and evaluate medicinal product information, including active ingredients and products’ anatomical and therapeutic classifications, from nearly 150 countries. Data covers both conventional medicines and herbal remedies. Data is continuously updated, with new releases twice a year, on 1 March and 1 September.

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• RRID
• 1 year ago - by Anonymous

Ontodog is a web-based ontology view generator. It can generate inSubset annotation ontology, user preferred label annotation ontology and subset of source ontology. Simply provide Ontodog input term file (Microsoft Excel file or tab-delimited text file), select one source ontology or enter your own source ontology and SPARQL endpoint, then set the settings for Ontodog output files and get the OWL (RDF/XML) Output files. Ontodog performs the basic ontology modularization-like function, i.e.,it automatically extracts all axioms and related terms associated with user-specified signature term(s). In addition, Ontodog includes extra features: (1) extracting all instance data associated with the retrieved class terms and annotations; and (2) recursively extracting all axioms and related terms indirectly associated with signature terms. More features are being added to Ontodog, such as relabeling preferred names for various ontology terms to fit in with the needs from a specific community. The Ontodog input data requires a source ontology and a list of user-specified signature terms in tab-delimited format. Ontodog provides the template files for generating the signature terms as the input terms file to download. There are several output options that the users can choose based on their needs. With more and more ontologies being developed, Ontodog offers a timely web-based package of solutions for ontology view generation. Ontodog provides an efficient approach to promote ontology sharing and interoperability. It is easy to use and does not require knowledge of SPARQL, script programming, and command line operation. Ontodog is developed to serve the ontology community for ontology reuse. It is freely available under the Apache License 2.0. The source code is made available under Apache License 2.0.

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• SciCrunch
• 15 years ago - by Anonymous

Integrated software platform for ion channel biophysics and neurophysiology.Used to explore dynamics of hidden states in memoryless system. Open source software suite for solving kinetic models, for report generation with publishable graphics, function fitting and scripting for new and repeated processing and AD/DA I/O. Can be applied to any data modeled with Markov kinetics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• RRID-Legacy
• 7 years ago - by Anonymous

Software R package that enhances text rendering in ggplot2 by allowing the use of Markdown, HTML, and rich text formatting for annotations, labels, and titles in plots.

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• RRID
• 1 year ago - by Anonymous

Tool for calling indels in Tumor-Normal paired sample mode.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool to draw CGO cylinder representing rotation axis for given transformation. Useful for drawing axes of rotational symmetry in oligomeric assembly.

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• RRID-Legacy
• 7 years ago - by Anonymous

Core provides access to XFe 96 Extracellular Flux Analyzer, seahorse technology, as well as additional services that include technical advice in experimental design, data analysis and basic training. Provides access to electrochemiluminescence immunoassays using MESO QuickPlex SQ 120. You can perform multiplex biomarker and cytokine assays, test for immunogenicity or toxicity, or we can help you develop your own unique assays. Core also provides access to ImageXpress Pico, the next generation of digital microscopy and access to SPECTRAMAX I3X, multi-mode microplate reader.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Distinctive Voices highlights innovations, discoveries, and emerging issues in an exciting and engaging public forum. Do you wonder how things work? What the future holds? If you are curious about the science and technology behind today''s hot topics, Distinctive Voices is for you! Spend an evening gaining insights on significant advances in medicine, biotechnology, energy, the environment, space exploration, and more. Learn from some of the best minds in the world including members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicinein presentations geared to the general public. Events are held in Irvine, California and Woods Hole, Massachusetts, with videos of past Distinctive Voices events available on our YouTube channel. Distinctive Voices was created in 2006 as a program of the National Academy of Sciences Communication Initiative to increase science literacy. The live programming hosted at the Beckman Center in Irvine, California received major funding from the Arnold and Mabel Beckman Fund of the National Academy of Sciences and National Academy of Engineering. Additional support is provided by The Edward Lifesciences Fund and Pacific Life Foundation. The program at the Jonsson Center in Woods Hole, Massachusetts is supported by the Frank Press Fund of the National Academy of Sciences, the Thomas Lincoln Casey Fund of the National Academy of Sciences, the Arthur L. Day Fund of the National Academy of Sciences, and the Kellogg Fund of the Institute of Medicine.

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• SciCrunch
• 15 years ago - by Anonymous

Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree.

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• RRID-Legacy
• 7 years ago - submitted by Chao Yang

Core provides in vitro HIV-1 neutralizing antibody assay services. Serves as resource for assessing breadth and potency of HIV-1 neutralizing antibodies, and for characterizing neutralization phenotype of HIV-1 isolates. Investigators send monoclonal antibodies or serum samples from vaccinated or HIV-1-infected individuals to the core for in vitro testing using the validated TZM.bl neutralizing antibody assay. The core also has the capability to phenotype primary HIV-1 isolates for sensitivity to broadly neutralizing antibodies. GCLP-compliant, In vitro testing of monoclonal antibodies or seurm samples, Validated TZM.bl neutralizing antibody assay, Phenotoyping of primary HIV-1 isolates.

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• RRID
• 1 year ago - submitted by Judith Webber