Curator Dashboard

Core offers comprehensive statistical and bioinformatic analysis, consultation, collaboration, and technical services.

• Resource
• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Private, non-profit institution dedicated to utilizing knowledge in science, engineering, technology and health to improve government decision making and public policy as well as increase public education and understanding. The council collects, analyzes and shares information and knowledge through activities such as consensus studies, meetings and workshops, and program and research management.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Software package designed to enable researchers with advanced tools for brain and image mapping. Many of the ANTS registration tools are diffeomorphic*, but deformation (elastic and BSpline) transformations are available. Unique components of ANTS include multivariate similarity metrics, landmark guidance, the ability to use label images to guide the mapping and both greedy and space-time optimal implementations of diffeomorphisms. The symmetric normalization (SyN) strategy is a part of the ANTS toolkit as is directly manipulated free form deformation (DMFFD). *Diffeomorphism: a differentiable map with differentiable inverse. In general, these maps are generated by integrating a time-dependent velocity field. ANTS Applications: * Gray matter morphometry based on the jacobian and/or cortical thickness. * Group and single-subject optimal templates. * Multivariate DT + T1 brain templates and group studies. * Longitudinal brain mapping -- special similarity metric options. * Neonatal and pediatric brain segmentation. * Pediatric brain mapping. * T1 brain mapping guided by tractography and connectivity. * Diffusion tensor registration based on scalar or connectivity data. * Brain mapping in the presence of lesions. * Lung and pulmonary tree registration. * User-guided hippocampus labeling, also of sub-fields. * Group studies and statistical analysis of cortical thickness, white matter volume, diffusion tensor-derived metrics such as fractional anisotropy and mean diffusion.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Software library to calculate Pathways Activation Levels. It takes file that contains gene symbols in HGNC format, their expression levels for one or more samples and calculates PAL values for each pathway in each sample.

• Resource
• RRID
• 3 years ago - by Anonymous

Sampling protocols produced by the BrainNet Europe Consortium generally with five types of dissection and brain processing procedures defined in all disease related protocols. * Fresh brain dissection * Fresh brain processing * Dissection of formalin-fixed brain * Histology and immunohistochemistry * Processing fresh brain

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software toolbox to facilitate quick and easy import, visualization and measurement for Event Related Potential (ERP) data. The toolbox can open and visualise ERP averaged data (Neuroscan, ascii formats), 2D/3D electrode coordinates and 3D cerebral tissue tesselations (meshes). All the features can be explored quickly and easily using the example data provided in the toolbox. The GUI interface is simple and intuitive.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Platform that systematizes interpretation of cancer genomes and makes it automatic. Web tool to annotate genomic alterations and interpret their possible role in tumorigenesis and in response to anti cancer therapies. Used to support identification of tumor alterations that drive disease and/or which may be therapeutically actionable. Analyses mutations including single nucleotide changes and small insertions/deletions, copy number alterations including gene amplifications and deletions and translocations.

• Resource
• RRID
• 3 years ago - by Anonymous

A resource and online book on neurology and neurosurgery. The book covers topics such as neurological symptoms, consciousness and unconsciousness, trauma, seizure disorders and dementia.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Open Source MATLAB toolbox and EEGLAB plugin for the design, prototyping, testing, experimentation with, and evaluation of Brain-Computer Interfaces (BCIs), and other systems in the same computational framework. It facilitates the design and development of new methods for cognitive state estimation and their use in both offline data analysis and real-time applications. BCILAB includes an easily extensible collection of currently over 100 methods from the literature (covering signal processing, machine learning and BCI-specific methods). Aside from supporting advanced BCI research, a special aim of BCILAB is to facilitate the adoption of machine learning and advanced statistical modeling for functional neuroimaging purposes in tandem with the EEGLAB platform. The toolbox offers multiple different interfaces which link to the same backend functionality, including a GUI, scripting support (MATLAB-based), APIs for real-time processing, and a variety of extension component interfaces. MATLAB programming is not strictly necessary, as most BCILAB features can be accessed from the GUI, although it is required for batch scripting and custom extensions. The strength of MATLAB-based software lies in its resources for leading-edge scientific computing, as well as in the good support for rapid prototyping, but BCI systems developed in it can be used for real-time out-of-lab experimentation, and can in principle be deployed without the need for a MATLAB license. However, due to the complexity and overhead of the MATLAB environment, the system is best used as a research platform, and not as a product development environment -- end-user software is ideally re-implemented in a compiled language, after a suitable approach has been identified and extensively tested. The process of identifying and testing an approach involves more than just computation, but also data exploration and investigation - an area which is helped by the deep integration with the EEGLAB platform. In the future, this integration will be further strengthened, bringing rich statistical learning and signal processing into routine EEG analysis workflows. The toolbox has been developed by C. Kothe at the Swartz Center, inspired by the preceding PhyPA BCI toolbox created by C. Kothe and T. Zander at the Chair for Human-Machine Systems, Berlin Institute of Technology.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Core specializes in areas of flow cytometry and cell sorting; light microscopy including confocal, widefield fluorescence, high content screening, lightsheet, slide scanning, highly multiplexed microscopy; and digital PCR / QPCR. It is located at University of Freiburg Medical Center and hosts institutions including Dept. of Medicine I, Center for Chronic Immunodeficiency (CCI), CCCF / DKTK, and Medical Faculty of University of Freiburg.

• Resource
• SciCrunch
• 3 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6, 2023. Software tool for quantitative neuroanatomical measurements in volumetric image data. Used to draw regions of interest for subsequent fMRI analysis.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Stereo Investigator system includes microscope, computer, and Stereo Investigator software. Software works with Brightfield, Multi-Channel Fluorescence, Confocal, and Structured Illumination Microscopes. System used to provide estimates of number, length, area, and volume of cells or biological structures in tissue specimen in areas of neuroscience including neurodegenerative diseases, neuropathy, memory, and behavior, pulmonary research, spinal cord research, and toxicology.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software toolbox is cell counting and distribution mapping platform which can be used to analyze serial two-photon tomography (STPT) data.

• Resource
• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Blogs for all things chemistry, hosted by Chemical & Engineering News (C&EN) magazine, where you will find blogs written by both C&EN staff and non-staff contributors on topics ranging from jobs to natural products chemistry to safety to the businesses of chemistry. CENtral Science currently includes the following blogs: * Artful Science: C&EN science writer Sarah Everts peers in to the laboratories that help museums and galleries authenticate, conserve, and restore art and artifacts. * Cleantech Chemistry: C&EN business writer Melody Voith looks at the business and technology strategies of companies that hope to serve the world's need for renewable energy, sustainable agriculture, clean water, and non-polluting manufacturing and transportation, among other cleantech sectors. * IYC 2011: CENtral Science's home for all things IYC 2011. * Just Another Electron Pusher: Contributors Christine Herman and Glenn Ernst profile people who've pursued professions away from the bench. They also write about their own personal quests for satisfying jobs that use their degrees but may not involve running any %$@& columns. * Newscripts: The companion blog to the like-named weekly C&EN column. Written primarily by C&EN science writers Lauren Wolf and Beth Halford, with contributions from the C&EN staff. * Terra Sigillata: Molecular cancer pharmacologist David Kroll writes about natural products, focusing on chemistry and pharmaceutical issues. * The Chemical Notebook: C&EN business writer Alex Tullo shares interesting tidbits from his reporter's notebook. * The Editor's Blog: The companion blog to the weekly print column by editor-in-chief Rudy Baum and deputy editor-in-chief Maureen Rouhi. * The Haystack: C&EN business writer Lisa Jarvis and science writer Carmen Drahl weed through pharma's molecular mountain to pluck out the drug developments worth noting. Also features frequent contributions from SeeArrOh, a Ph.D chemist working in industry. * The Safety Zone: C&EN science writer Jyllian Kemsley and safety consultant Russ Phifer cover chemical safety issues in academic and industrial research labs and in manufacturing. * Transition States: A blog about undergrads, by undergrads. Chiral Jones, a senior working on organic chemistry, and Sidechain Bob, a junior in the field of chemical biology, tell their stories of the graduate school experience. Over time, some blogs will retire and others will be added. Their blog network is intentionally a small one, and bloggers are added on an invitation basis. Proposals or blog suggestions may be submitted. It's not a community without your voice, so please contribute either as a commenter or a blogger.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

A set of useful accessory programs to the LINKAGE package. It simplifies the performance of a large array of parametric and nonparametric tests for linkage and association on data entered in LINKAGE format pedigree and parameter files. (entry from Genetic Analysis Software)

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Core provides liquid chromatography and gas chromatography mass spectrometry instrumentation for selective identification and reproducible quantification of trace-level biomolecules in complex samples. Services include qualitative, quantitative and structural analysis of proteins, lipids, metabolites, pesticides, pharmaceuticals and volatile organic compounds. Tests can be performed as long as molecules of interest are amenable to ionisation technique employed in source of mass spectrometer. Depending on instrument type, samples may be solid, liquid or gas. Mass spectrometry platforms include Liquid Chromatography Mass Spectrometry (LC-MS) and Gas Chromatography Mass Spectrometry (GC-MS). Analysis include volatile organic compounds (odour analysis),pharmacokinetics (bioavailability, bioefficacy),drug development (determining structures of drugs and metabolites),clinical testing (biomarkers discovery and endogenous compounds),genomics (oligonucleotide sequencing) epigenetics (global DNA methylation analysis),environmental research (testing water, soil, food and air quality).

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

A non-profit charity dedicated to providing education about animal research for the purpose of protecting medical and scientific progress. The organization seeks to provide accurate and incisive information to foster a balanced public debate on animal research issues. They work to do outreach by distributing timely and relevant news, information and analysis about animal rights extremism to the research community.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A workflow-oriented environment focused on biomedical image computing and simulation. The open source framework is extensible through plug-ins and is focused on building research and clinical software prototypes. Gimias has been used to develop clinical prototypes in the fields of cardiac imaging and simulation, angiography imaging and simulation, and neurology.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Software R package for training and practicing epidemiologists including methods for two-way and multi-way contingency tables.

• Resource
• RRID
• 3 years ago - by Anonymous

A partnership that leads and inspires the world in achieving universal access to HIV prevention, treatment, care and support. UNAIDS publishes a new Report on the global AIDS epidemic every two years. The Report draws upon and publishes the best available data from countries and provides an overview and commentary on the epidemic and the international response. UNAIDS fulfills its mission by: :- Uniting the efforts of the United Nations system, civil society, national governments, the private sector, global institutions and people living with and most affected by HIV; :- Speaking out in solidarity with the people most affected by HIV in defense of human dignity, human rights and gender equality; :- Mobilizing political, technical, scientific and financial resources and holding ourselves and others accountable for results; :- Empowering agents of change with strategic information and evidence to influence and ensure that resources are targeted where they deliver the greatest impact and bring about a prevention revolution; and :- Supporting inclusive country leadership for sustainable responses that are integral to and integrated with national health and development efforts. Sponsors: This resource is supported by: Advocacy partners; Civil society; Donors; Global Coalition on Women and AIDS; Global Fund to Fight AIDS TB and Malaria; People living with HIV; Private sector, and UN Family.

• Resource
• SciCrunch
• 14 years ago - by Anonymous