Curator Dashboard

CRC houses two complementary resources: the High-Performance Computing section, providing over 35,000 cores of computational power with the associated support infrastructure for both hardware and installed software, and the Cyberinfrastructure section, empowering Faculty and industry partners to develop research software and environments that support advanced data and information processing services including acquisition, storage, management, integration, mining

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

CGB offers range of genomic services, including high-throughput DNA/RNA extraction, library preparation, next-generation sequencing, and bioinformatic analysis

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides high-throughput genomics services including: genomic DNA sequencing, transcriptome RNA sequencing, miRNA sequencing, methylome or targeted methylation sequencing, protein DNA/RNA interaction (ChIP-seq, ATAC-seq and CLIP-seq), 10x single cell or single nuclei sequencing, and SNP genotyping.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. Facility comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL).

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides study design and data analysis for health-related research, including grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core offers services related to biospecimen and data collection in support of cancer research. Provides collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to clinic, and probe the biology underlying clinical and population phenomena.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing and storage services with focus on consistent quality and sample integrity.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Facility where IUSM and external investigators can request studies within broad spectrum of rodent behavioral paradigms. Housed on the fourth and fifth floors of Stark Neurosciences Research Institute in the Neurosciences Research Building, the core, available to all IU School of Medicine investigators. Core validates all assays; allows for testing of pharmacological or other manipulations to study disease models; incorporates necropsy endpoints to behavioral assays as needed; provides guidance on interpretation and analysis of data.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Clinical testing lab that performs targeted metabolomics analyses designed to diagnose and manage patients with inherited metabolic disease.Services include Quantitative Acylcarnitine panel,Quantitative Amino acid panel,Quantitative Methylmalonic acid,Quantitative Free and Total Carnitine Analysis,Semi-Quantitative Urine Organic Acid Profile,Blood Spot Analyte Quantification,Custom Development of Quantitative Metabolite Assays.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Flow Cytometry Core at Seattle Children's Research Institute, offers cell analyzer and sorter capabilities to researchers across the institute.

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• RRID
• 2 years ago - by Anonymous

Service facility which provides instrumentation and image analysis on recharge basis. Offers full specimen preparation and imaging services. Specimen preparation for electron microscopy studies including negative staining, plastic embedding, ultramicrotome and immunogold.

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• RRID
• 2 years ago - by Anonymous

Software tool to identify barcode and primer sequences in PacBio single-molecule sequencing data. It powers the Demultiplex Barcodes GUI-based analysis application,

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• RRID
• 2 years ago - by Anonymous

Software package to compute distance matrices in sparse or dense mode with GPU or CPU.

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• RRID
• 2 years ago - submitted by Pavel Akhtyamov

Software application for model-based dimensionality reduction of scRNA-seq data. Quantifies uncertainty in each cell's latent position and leverages these uncertainties to assess confidence associated with given cell clustering. On real and simulated single-cell data produces low-dimensional embeddings that better capture relevant biological information while removing unwanted variation. Used for model-based dimensionality reduction for single-cell RNA-seq with generalized bilinear models.

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• RRID
• 2 years ago - by Anonymous

Software R package for dimension reduction of non-normally distributed data. Generalized PCA for non-normally distributed data.

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• RRID
• 2 years ago - by Anonymous