Curator Dashboard

Provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility. Histology Core is core facility of the Indiana Center for Musculoskeletal Health and part of the Bone and Body Composition Core of the Indiana Clinical Translational Sciences Institute (CTSI). Histology Core provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Offers comprehensive services and support for genomics experiments and bioinformatics analysis. This includes next generation Illumina sequencing, a variety of standard and specialty DNA and RNA library construction methods, consultation, and analysis support.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides evidence-based services, training, coaching and consultation across range of local community and state stakeholder networks e.g., families, medical providers, school personnel, community organizations. This involvement and integration in addressing the behavioral, educational, and vocational needs of consumers across a range of ages i.e., early childhood through adulthood, functioning and disability types has assisted in: providing consultative expertise related to assessment and intervention with autism spectrum disorder and related developmental e.g., developmental and/or intellectual disabilities or neurodevelopmental disorders; reaching extensive audience for recruitment efforts; facilitating efforts related to community-based mixed methods, clinical trials and other research endeavors e.g., survey development and dissemination, behavioral assessment and intervention related to individuals with ASD/DD/ID across lifespan.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides access to genome editing technologies by assisting with generation of genetically modified mouse models and cell lines.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Home to virtually all laboratory animals. Services include Procurement, Animal care, Breeding, Training,Limited procedures for research.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides range of evaluation and data services to support client needs.Through consulting, evaluation, methodology, and training, we work to fill gaps and improve and empower data driven decision making.At the proposal stage of grants, we can design evaluation plans to meet your project needs, with the associated narrative text, budget, and letter of collaboration, as needed. We can also fill gaps post-award, or provide support with internal funding. We can assist with logic models, Broader Impacts, methodologies, needs assessments, survey design and implementation, support with Institutional Review Board applications, and trainings in our areas of expertise.

• Resource
• RRID
• 2 years ago - by Anonymous

Internationally recognised shared resource laboratory which provides researchers with access to equipment, education and expertise that enables isolation, separation and analysis of cell populations.

• Resource
• RRID
• 2 years ago - by Anonymous

Software application as minimap2 frontend for PacBio native data formats. SMRT C++ wrapper for minimap2's C API.

• Resource
• RRID
• 2 years ago - by Anonymous

Fully automated research stainer that automates staining step which ensures that microscope slides are produced with consistent, reproducible, and efficient way. Utilizes biological assay called immunohistochemistry.BOND RX model expands on the capabilities of IHC by including other assays.

• Resource
• SciCrunch
• 2 years ago - submitted by Christina St

Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Facility provides access to instrumentation enabling users to collect data for high-resolution single particle reconstructions and tomographic studies of cells and larger complexes.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Open access multimodal 3D atlases of developing mouse brain that can be used to integrate mouse brain imaging data for visualization, education, cell census mapping, and more. Atlas ages include E11.5, E13.5, E15.5, E18.5, P4, P14, and P56. Web platform can be utilized to visualize and explore the atlas in 3D. Downloadable atlas can be used to align multimodal mouse brain data. Morphologically averaged symmetric template brains serve as the basis reference space and coordinate system. Anatomical labels are manually drawn in 3D based on the prosomeric model. For additional references, the P56 template includes templates and annotations from the aligned Allen Mouse Brain Common Coordinate Framework (Allen CCFv3) and aligned Molecular Atlas of the Adult Mouse Brain.

• Resource
• RRID
• 2 years ago - by Anonymous

Software R package to compute various confidence intervals for the Kaplan-Meier estimator, namely: Peto's CI, Rothman CI, CI's based on Greenwood's variance, Thomas and Grunkemeier CI and the simultaneous confidence bands by Nair and Hall and Wellner.

• Resource
• RRID
• 2 years ago - by Anonymous

Software R package as collection of functions to compute the Clopper-Pearson Confidence Interval and the required sample size. Density, distribution function, quantile function and random generation for the Generalized Binomial Distribution.Enhanced model for burn-in studies, where failures are tackled by countermeasures.

• Resource
• RRID
• 2 years ago - by Anonymous

Core facilities pre-clinical studies of orthopedic devices intended for animal and human use, clinical studies of treatment and prevention of respiratory diseases in horses and animal clinical trials evaluating the treatment of bladder cancer in Scottish Terriers, an animal model of human bladder cancer.

• Resource
• RRID
• 2 years ago - submitted by Edyta Vieth

Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development

• Resource
• SciCrunch
• 2 years ago - submitted by Edyta Vieth