We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Core for genomics research in Carl R. Woese Institute for Genomic Biology. Coordinates with IGB and National Center for Supercomputing Applications to provide technical expertise in high-performance computational biology.
Core provides expertise in characterizing proteins from diverse systems. Provides proteomics services including customized sample preparation, protein identification, detection of post-translational modifications, isotopic label based and label-free quantitation, and intact protein characterization. Equipped with high resolution mass spectrometers with nanoflow liquid chromatography systems or chip-based robots. Core uses software systems such as Mascot, Proteome Discoverer, Byonic, and MaxQuant for analysis of raw mass spectrometry data. Provides assistance in protein quantitation and deeper downstream bioinformatics analysis including gene ontology, visualization of protein networks, and pathway analysis. Consultations are always welcome.
Provides service and instrumentation to support basic, environmental, agricultural, and translational medical research.
Facility offers amplicon sequencing libraries, 16S sequencing, PacBio Revio long read 16S sequencing, custom long read amplicon libraries Standard Biotools (formerly Fluidigm) multiprimer amplicons, high throughput Gene Expression and SNP genotyping using Standard Biotools microfluidic system, Illumina beadchip arrays for genotyping and methylation analysis.
Core identifies and quantifies small molecules from variety of origins such as biological tissue, blood, serum, plasma, cell, cell medium, urine, feces, among others. Provides support for untargeted and targeted metabolite profiling, detecting such compounds as sugars and sugar phosphates, alcohols, amine and polyamines, amino acids, fatty acids, complex lipids, nucleotides, organic acids, phenolics, bile acids, steroids/hormones, neurotransmitters and neuromodulators, phthalates, and many more emerging metabolites. Helps execute projects, including protocol development, sample preparation, instrument method development, instrument data acquisition, and data processing.Multiple complementary analytical methods are utilized with mass spectrometry. Our laboratory has mass spectrometers, including liquid chromatograph-mass spectrometers such as Agilent 6560 ion mobility Q-TOF and Agilent 6546 Q-TOF systems, in addition to our Thermo Fisher Q Exactive hybrid quadrupole-orbitrap, Thermo Fisher Altis triple quadrupole, Sciex 6500+ triple quadrupole, and Sciex 5500 hybrid triple quadrupole-ion trap (QTRAP), as well as gas chromatograph-mass spectrometers including Agilent 5977A, Agilent 5975C, and Agilent 5973.
Facility, couples cytometry with microscopy, genomics and proteomics using instrumentation, expertise and services. Utilizes advanced super resolution microscopy techniques to gain understanding of cell sorting, analysis and enable cutting-edge spatial and single cell and multi-omics services.
Kit for dissociation of tissue using papin
Tutorial to custom-design and -fit implants to continuous and discontinuous skull surfaces. Universal Guide for Skull Extraction and Custom-Fitting of Implants to Continuous and Discontinuous Skulls.
Assist researchers in development and analysis of various in vivo neurodegenerative and cancer models including humanized and germ-free animals. Facility has capacity to house different transgenic and germ-free mouse strains in more than 2500 IVC cages within SOPF breeding barrier.
Core imaging facility operating out of the University of Illinois. Offers many imaging modalities, including confocal, micro- and nano-CT, electron microscopy, scanned probe microscopy, Raman, and fluorescence. Assists users in preparing and collecting data on various projects.
Provides support to UC research through engineering, design, fabrication, and repair of custom equipment. We can take your ideas, napkin sketches, drawings, and models and turn them into real parts, machines, tools, and systems. Services: prototyping, welding, fabrication, machining, electrical, repairs, misc. technical labor.
Core supports molecular and magnetic resonance imaging. Provides facilities, equipment, and training for researchers across range of disciplines. Each BIC tool is supported by research scientists available to assist with study design, data collection, and data post-processing.
Computerized matching of cases to controls using greedy matching algorithm with fixed number of controls per case. Controls may be matched to cases using one or more factors (X’s).
Software pipeline system for ReproStat, written primarily in OCTAVE/MATLAB. It facilitates reproducible, inclusive, and efficient neuroimaging analyses.
Web ecosystem for sharing metadata. Designed to annotate datasets by creating metadata file to attach to storage space. Allows users to add descriptive metadata to datasets produced within collective of research unit, platform, multi-partner project, etc. to fit to data management plan about data organization and documentation, data storage and frictionless metadata sharing.
Software tool to analyze scratch assays. It measures the area of wound in cellular tissue on stack of images representing time-series.
XLS model of ImageXpress Micro System to leverage large field-of-view optics to map macro-structures with minimal tiling. Querying of large cell populations is accelerated three fold, speeding up the characterization of highly heterogeneous samples or identification of rare sub-populations. Combined with software, the custom designed ImageXpress Micro System provides platform to translate new discoveries into scientific breakthroughs.
Web toolkit for studies of large scale T2T genomes. Collection of tools designed for T2T genome assembly and characterization, including reference guided genome assembly, ultra long sequence based gap filling, telomere identification, and de novo centromere prediction. Includes four modules: AssemblyMapper, GapFiller, TeloExplorer, and CentroMiner. Modules can be used alone or in combination with each other for T2T genome assembly and characterization.