We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Integrates technology in single-particle cryogenic electron microscopy. Thermo Scientific Talos L120C Transmission Electron Microscope is available for visualizing nanoparticles, negatively stained proteins or conventional biological samples. It can be operated at 80kV or 120kV. Thermo Scientific Glacios 200 kV cryogenic TEM is equipped with both Ceta-16M camera and TFS Falcon 4 direct electron detector, in addition to Selectris Energy Filter. This system is able to generate images for atomic resolution structures for single particle analysis projects. Glacios also includes software for micro-Electron Diffraction data set collection. Available services include Training and access to the Mark IV Vitrobot plunge freezer,Training and access to the Talos L120C TEM system, Training and access to the Glacios 200 kV cryogenic TEM system, Assisted TEM analysis by CASB personnel.
Provides standardized mass spectrometry-based services for detection of metabolites in various biological samples. Offers development of novel techniques, access to advanced analytical instrumentation, guidance with experimental design, support with post-acquisition data analyses and assistance with publications and planning future studies.
Software R package to estimate mutation rates and quantify somatic selection in cancer.
University of Copenhagen Novo Nordisk Foundation Center for Basic Metabolic Research Metabolomics Platform Core Facility is equipped with a high resolution mass spectrometer with two distinct separation technologies - a second generation dual Trapped Ion Mobility Spectrometry (TIMS) analyzer which provides collision cross section values and Parallel Accumulation Serial Fragmentation (PASEF) which allows downstream selection of precursor ions for fragmentation. The mass spectrometer is coupled with Agilent 1290 Bio UPLC, with binary solvent pump, multi-sampler and thermostatted column oven.
Software tool to predict phage replication cycle.
Core partners with University of Michigan research community to achieve animal welfare standards in pursuit of impactful science. Provides training laboratory animal veterinarians and veterinary care to all animals used at the University of Michigan.
Core ensures that animal welfare standards are maintained along with conduct of accurate, valid scientific research through supervision, coordination, training, guidance, and review of every project proposed to include use of vertebrate animals or cephalopods at University of Michigan.
Provides next generation services. Provides centralized expertise in advanced methods that enables all researchers to effectively exploit them for making scientific discoveries.
Software label transfer tool for single-cell RNA sequencing analysis. Scalable, Interpretable Modeling for Single-cell RNA-seq data classification.
Public land-grant research university in Orono, Maine. It was established in 1865 as the land-grant college of Maine and is the flagship university of the University of Maine System.
Funding organization for neurodegenerative disorders and use of AI in it. 501(c)(3) philanthropic initiative that seeks to accelerate the use of artificial intelligence (AI) in the fight against neurodegenerative diseases.
Core offers imaging for diverse applications, including multi-color experiments, live sample imaging, protein colocalization, large sample tiling, and Z-stack 3D/4D imaging, as well as weak label detection. Provides expert guidance in microscopy and image analysis, training and support to advance research across various model organisms.
Software R package to perform feature specific quantile normalization. Designed to quantile normalize each feature in data set according to its corresponding feature in target distribution. This eliminates distribution based differences resulting from the use of different gene expression profiling platforms.
Software for evaluating, comparing and presenting real-time interaction data. Used for quantification of kinetics and affinity through curve fitting, with large number of binding models to choose from. Can extract experimental information from measurement, requiring minimal user input.
Core includes instrumentation for structural biology with focus on cryo-electron microscopy. Used for imaging ranging from atomic resolution to whole cells, with emphasis on linking structural and dynamics information with biological functions.
Software quality control tool for digital pathology slides. Used to identify and delineate slide artefacts and discover cohort-level outliers.
Software quality assurance and checking tool for quantitative assessment of magnetic resonance imaging and computed tomography data. Used for quality control of MR imaging data.
Software multi-modality post-processing suite for SPECT, CT, PET, MR, Optical and and Autoradiography imaging data.
Software Python package that plots data on cortical surface.