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Core provides expertise and support for biomedical research to assess and improve animal models of disease. Performs detailed characterization of animal models across species and research areas via histopathology, DNA and RNA interrogation, and spatial assessment assays.
Software cloud-optimized WDL workflow that performs cell type label transfer using scVI and scANVI (single-cell ANnotation using Variational Inference) deep generative models. It integrates single-cell RNA-seq (GEX) and, optionally, ATAC-seq data with an annotated reference dataset to transfer cell type labels via semi-supervised learning.
Biotechnology and diagnostics company specializing in "liquid biopsy" technologies to detect and isolate rare cells like circulating tumor cells (CTCs) from blood or tissue samples. They provide precise single-cell analysis tools used in cancer research and personalized medicine. Offers commercial rare-cell laboratory service providing CD138-positive immunomagnetic enrichment of plasma cells from peripheral blood and immunofluorescence-based plasma-cell identification and enumeration, delivering an enriched circulating multiple myeloma cell fraction for downstream analysis.
Facility offers sequencing services including expertise, sequencing experiment design, data analysis. Provided instruments include Illumina MiSeq and NextSeq500 sequencing platforms for low and medium throughput, which can supply single or paired reads from 75 to 600 cycles, Oxford NanoPore Technologies GridION and PromethION platforms and MinIONs. Core helped to develop software tools for MinION data analysis.
United States based educational platform dedicated to changing research culture by providing comprehensive educational materials, promoting best practices, and fostering a community committed to improving research reliability. Helps researchers learn and implement scientific rigor, such as proper experimental design, avoiding bias, and statistical analysis. Offers modules that address common issues such as experimental design, causal inference, avoiding statistical fallacies, and writing transparently reproducible code.
National, peer led consortium of institutions that advocates for systemic changes to improve research quality, training, and open science practices. It unites researchers, universities, funders, and publishers to promote open research practices, share best practices, and reform how researchers are evaluated and rewarded. Provides training resources and workshops to help researchers adopt transparent methods, such as sharing open data and code. It operates grassroots local networks at universities across the country, connecting researchers to exchange ideas and collaborate across different career stages and disciplines.
Core provides advanced instrumentation, consultation, and support for flow cytometry, light and electron microscopy, and small-animal imaging. Services include confocal microscopy, multi-plex whole slide imaging, conventional, widefield epifluorescence microscopy, Electron Microscopy, in vivo small animal PET, SPECT, CT, X-Ray, white light, fluorescence, and bioluminescence imaging, in vitro and in vivo X-Ray irradiation, multi-parameter flow cytometry, including conventional and spectral technologies, cell sorting, imaging cytometry, and advanced data analysis support.
Core provides sequencing using Illumina next-generation sequencing and ONT long read technologies. Offers library preparation services for genomes, exomes, transcriptomes, and ChIP-seq experiments, expertise on the best approach for samples, depending on the quality of nucleic acids, scope of project, and available budget.
Software R code to apply Stages of Reproductive Aging Workshop + 10 stages to prospectively collected vaginal bleeding data among a cohort of Black women aged 40–55 years. Used to apply STRAW+10 stages to prospectively tracked menstrual bleeding data in a longitudinal cohort study of perimenopausal women.
Core provides expertise in radiochemistry, PET tracer development, preclinical PET and MRI imaging, cancer modelling, and advanced image analysis. Supports translational imaging research, with strengths in molecular imaging, pharmacodynamic biomarker development, and AI-enabled image analytics. Provided instruments include a GE PETtrace 800 cyclotron, radiosynthesis platforms, and small-animal NanoScan PET/MRI system. Services include expertise in both PET and MRI acquisition and analysis, supporting studies in cancer biology, metabolism, and therapy response.
Software tool for predicting protein functional association by analysis of conservation of genomic contex. Takes a list of NCBI protein accessions as input, clusters neighbourhood-encoded proteins into homologous groups using sensitive sequence searching, and outputs a graphical visualization of the gene neighbourhood and its conservation, along with a phylogenetic tree annotated with flanking gene conservation.
Concentrator with UVS850DDA Universal Vacuum System is designed for solvent removal and sample concentration with integrated vacuum control and refrigerated/condensation components. Used to quickly evaporate or remove solvents from samples. It combines vacuum pressure, mild centrifugation, and heat to safely concentrate biological and chemical samples without risking degradation.The DDA (Dual-valve Dual-application) designation means it is specifically chemically resistant and rated for aggressive conditions.
Software R package and web application designed for the quality control (QC), exploratory data analysis (EDA), visualization, and statistical analysis of complex biological omics data. Provides functionality for quality control processing and statistical analysis of mass spectrometry (MS) omics data, in particular proteomic (either at the peptide or the protein level), lipidomic, and metabolomic data, as well as RNA-seq based count data and nuclear magnetic resonance (NMR) data. This includes data transformation, specification of groups that are to be compared against each other, filtering of features and/or samples, data normalization, data summarization (correlation, PCA), and statistical comparisons between defined groups.
Software platform by Thermo Fisher Scientific designed for identifying, comparing, and interpreting small molecules in complex biological, environmental, and forensic samples. It uses customizable workflow, known as nodes, to automate mass spectrometry data processing, spectral library searching, and statistical analysis.Compound Discoverer is integrated with SIRIUS (via a custom workflow node) to bridge the gap between high-resolution MS/MS data and confident molecular identification. While Thermo Scientific’s Compound Discoverer excels at library searching and statistical analysis, SIRIUS provides powerful in silico tools to accurately predict molecular formulas, chemical classes, and de novo structures. High-resolution mass spectrometry (HRMS) data analysis software for untargeted metabolomics, lipidomics, and contaminant screening. Utilizes modular workflows to extract features, match spectra against libraries like mzCloud, and confidently identify complex organic compounds.
Software tool as peptide retention time predictor using peptide encoding based on atomic composition that allows the retention time of (previously unseen) modified peptides to be predicted accurately. Retention time prediction for peptides.
Web tool and predictive model used by researchers to identify which small protein fragments (peptides) will be presented by human leukocyte antigen (HLA) proteins on the surface of cells. It is heavily used in the development of cancer immunotherapies and personalized
Centralized molecular and analytical core that provides full service genomic library preparation, high-throughput DNA/RNA extractions, small molecule analysis, and routine isolation and storage of microbial strains. Specializes in environmental samples and offer low-cost fees for training and walk-in instrument use. Functions as a bio-repository of experimental arthropod models including Drosophila and other endemic insects
Database provides age specific reference templates and segmented brain volumes for participants ranging from 2 weeks to 89 years of age. It is highly utilized for pediatric and lifespan neurostructural studies to prevent misspecifications caused by using adult only templates. Consists of average MRI templates, segmented partial volume estimate volumes for GM, WM, T2W-derived CSF. The database is separated into head-based and brain-based averages. The data are separated by ages in months, years, 6-month, or 5-year intervals. The templates are grouped into first year (2 weeks through 12 months), early childhood (15 months through 4 years), childhood (4 years through 10 years), adolescence (10.5 years through 17.5 years) and adults (18 years through 89 years). Tools for cortical source analysis of EEG and ERP are provided. These tools are based on the average MRI templates, segmenting, and atlases.
Atlas provides a comprehensive framework for dissecting hormonal impact on health and disease. Maps the human endocrine system. Provides a comprehensive map of over 14 million cells to track hormonal signaling. A single cell map uses single cell transcriptomics to map hormone production and action across 47 disease-free human tissues at cellular resolution.
Software toolkit for predicting hormone producing and receiving strength in single cell datasets.