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Registry for describing, sharing and publishing scientific computational workflows. Aims to facilitate discovery and re-use of workflows in accessible and interoperable way. This is achieved through extensive use of open standards and tools, including CWL, RO-Crate, Bioschemas and GA4GH's TRS API, in accordance with FAIR principles.WorkflowHub supports workflows of any type in its native repository.
Core is equipped with protein separation and mass spectrometry equipment as well as trained personnel to perform comparative analyses of complex protein mixtures and to identify differentially-expressed proteins. Offers guidance and consultation.
Offers high-throughput sequencing and genotyping services utilizing cutting edge Illumina and Xoford Nanopore systems. Sequencing facility in Oklahoma. Equipped with an Illumina NovaSeq 6000, Illumina NextSeq 2000, Illumina MiSeq, Illumina iSeq, Oxford Nanopore PromethION 2, and Oxford Nanopore MinION,Illumina iScan and Autoloader for extremely-high throughput genotyping projects. Core can perform all aspects of NGS, ranging from whole genome sequencing to single-cell transcriptomics.
Mass spectrometry based proteomics.
Facility houses 13 high-end light microscopes including point scanning and spinning disk confocals, Airyscan, 3D-STED super resolution, widefield and TIRF systems. Core offers training, consultation and access to powerful analysis computers with licensed softwares.
Light and fluorescence microscopy core facility with Zeiss, Nikon, 3I, Leica and Olympus Microscopes. Distributed light microscopy core facility consisting of inverted and upright confocal microscopes (laser scanning and spinning disk) some with superresolution, atomic force microscopy, total internal fluorescence reflection (TIRF), high throughput multicolor imaging of fixed tissue sections or cells on slides, and live cell imaging in most modalities.
Agilent NovoCyte 3000 Flow Cytometer with 3 lasers (488, 405, 640 nm) and up 13 colors. 6 colors from violet laser; 5 colors from blue laser; 2 colors from red laser. NovoExpress software used for acquisition.
Provide Rockefeller University researchers and collaborators with infrastructure necessary for computationally intensive workloads, as well as training and support for using these resources.
Software Python package for external validation of machine learning models with adaptive sample splitting.
A classifier tool based on deep learning methods for the classification and annotation of large-scale fungal ITS sequences.
Software classifier tool based on deep learning methods for classification and annotation of large-scale fungal ITS sequences. Used for fungal species classification.
Web-service that can generate highly accurate biomolecular structure predictions containing proteins, DNA, RNA, ligands, ions, and also model chemical modifications for proteins and nucleic acids in one platform. Powered by AlphaFold 3 model.
SMARTER-database aims to collect data produced by SMAll RuminanTs breeding for Efficiency and Resilience project and to merge them with already available genotype data. Used to explore genomic diversity in small ruminants.
Software tool as Oxford Nanopore basecaller. Used to determine nucleotide sequence.
Software suite based on BlobTools to aid researchers in identifying and isolating non-target data in draft and publicly available genome assemblies. Used for genome assembly QC and contaminant cobiont detection and filtering. Can be used to process assembly, read and analysis files for fully reproducible interactive exploration in the browser-based Viewer. Can be used during assembly to filter non-target DNA. BlobToolKit is comprised of four distinct components: BlobTools2 (command line tools to create and filter datasets), Specification (a formal specification and validator for the JSON-based data format), Viewer (interactive dataset visualization), and INSDC-pipeline (a Snakemake pipeline to run the BlobToolKit workflow on publicly available datasets).
AMI Imaging Center houses advanced, commercial light microscopes. These instruments are tailored for use in the life sciences and provide high spatial and temporal resolution to study variety of biology.
The Agilent 7250 Series Accurate-Mass Q-TOF is a stand-alone Quadrupole Time-of-Flight (Q-TOF) mass spectrometer coupled with an Agilent 8890 GC.
The Exploris 240 is a high resolution Orbitrap MS instrument from Thermo with resolution up to 240,000. It is coupled to a Vanquish UPLC system.
A triple quadrupole mass spectrometer from Waters Corporation couple to an Acquity Premier UPLC system for quantitative analyses.
The Bruker Impact II is a high resolution quadrupole-time of flight mass spectrometer. It is equipped with a VIP-HESI source and is coupled to an Agilent 1290 UPLC system.