Curator Dashboard

Core offers services related to biospecimen and data collection in support of cancer research. Provides collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to clinic, and probe the biology underlying clinical and population phenomena.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing and storage services with focus on consistent quality and sample integrity.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Facility where IUSM and external investigators can request studies within broad spectrum of rodent behavioral paradigms. Housed on the fourth and fifth floors of Stark Neurosciences Research Institute in the Neurosciences Research Building, the core, available to all IU School of Medicine investigators. Core validates all assays; allows for testing of pharmacological or other manipulations to study disease models; incorporates necropsy endpoints to behavioral assays as needed; provides guidance on interpretation and analysis of data.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Clinical testing lab that performs targeted metabolomics analyses designed to diagnose and manage patients with inherited metabolic disease.Services include Quantitative Acylcarnitine panel,Quantitative Amino acid panel,Quantitative Methylmalonic acid,Quantitative Free and Total Carnitine Analysis,Semi-Quantitative Urine Organic Acid Profile,Blood Spot Analyte Quantification,Custom Development of Quantitative Metabolite Assays.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Flow Cytometry Core at Seattle Children's Research Institute, offers cell analyzer and sorter capabilities to researchers across the institute.

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• RRID
• 2 years ago - by Anonymous

Service facility which provides instrumentation and image analysis on recharge basis. Offers full specimen preparation and imaging services. Specimen preparation for electron microscopy studies including negative staining, plastic embedding, ultramicrotome and immunogold.

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• RRID
• 2 years ago - by Anonymous

Software tool to identify barcode and primer sequences in PacBio single-molecule sequencing data. It powers the Demultiplex Barcodes GUI-based analysis application,

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• RRID
• 2 years ago - by Anonymous

Software package to compute distance matrices in sparse or dense mode with GPU or CPU.

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• RRID
• 2 years ago - submitted by Pavel Akhtyamov

Software application for model-based dimensionality reduction of scRNA-seq data. Quantifies uncertainty in each cell's latent position and leverages these uncertainties to assess confidence associated with given cell clustering. On real and simulated single-cell data produces low-dimensional embeddings that better capture relevant biological information while removing unwanted variation. Used for model-based dimensionality reduction for single-cell RNA-seq with generalized bilinear models.

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• RRID
• 2 years ago - by Anonymous

Software R package for dimension reduction of non-normally distributed data. Generalized PCA for non-normally distributed data.

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• RRID
• 2 years ago - by Anonymous

Software R package to analyse overdispersed counts or proportions.

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• SciCrunch
• 2 years ago - by Anonymous

Software C/C++ tool for efficient genotyping bi-allelic SNPs on single cells. You can use cellsnp-lite after read alignment to obtain the snp x cell pileup UMI or read count matrices for each alleles of given or detected SNPs.

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• SciCrunch
• 2 years ago - by Anonymous

Software mutable, self-balancing interval tree for Python 2 and 3. Queries may be by point, by range overlap, or by range containment.

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• SciCrunch
• 2 years ago - by Anonymous

Software tool for ultra fast eQTL analysis via large matrix operations.

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• SciCrunch
• 2 years ago - by Anonymous

Software R package for fitting generalized linear mixed models and extensions, built on Template Model Builder.

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• SciCrunch
• 2 years ago - by Anonymous

Software tools for developing Ordinary Least Squares regression models.

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• RRID
• 2 years ago - by Anonymous

Software R package to detect differential transcript usage from data generated by commonly used polyA-captured scRNA-seq technology.

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• SciCrunch
• 2 years ago - by Anonymous