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Industrial x-ray facilities with microfocus and high energy 2D and CT systems. Provides instruments for biological CT scanning as service.
Software that predicts three phage replication cycles, including virulent, temperate, and chronic cycles in viral sequences. Replication cycle decipher for Phages.
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Gamma counter with optional internal balance specifically designed for nuclear medicine applications. Dedicated to Nuclear Medicine and PET applications. Used to measure gamma radiation emitted by radionuclide in samples.
Software tool as sequence alignment algorithm that combines SIMD instruction sets and thread acceleration. Pairwise and multiple sequence alignment accelerated by simd and threads
Provides computational services including hardware, software and expertise for complex analysis and modelling .
Comprehensive database about Gram-positive model bacterium Bacillus subtilis. Provides curated information about its genes and proteins, as well as intricate protein–protein interactions, regulatory elements, expression data and metabolic pathways.
Core provides access to flow and mass cytometers, support equipment, and associated software and services. Our instrumentation affords the ability to perform almost every published flow and mass cytometry protocol.
Facility for high-throughput sequencing. Provides Next-Generation Sequencing services, supports library preparation and quality control for various applications including RNA-Seq: rRNA depletion-total RNA, mRNAseq; DNA-Seq: ChIP-Seq, Cut andTag seq, Hi-Cseq, Micro-Cseq, WGS; Single Cell: scRNAseq, scATACseq, snRNAseq, seRNAseq.
Mass spectrometry core facility. Facility uses chromatography systems, mass spectrometers and workflows for in-depth analysis of biomolecules.
Facility for cryo-electron microscopy. Provides microscope access, training as well as scientific and technical support for MPIB-internal users wishing to perform cryo-EM experiments, from sample preparation to data processing.
Facility for bioorganic chemistry and biophysics. Offers services for studying protein structure and folding, protein-protein or protein-ligand interactions and protein complex formation, synthesis, purification and characterization of organic compounds, automated solid phase synthesis of peptides.
Facility for bioinformatics. Offers to assist wet-lab researchers in our institute for their bioinformatics data analysis.
Facility for protein production. Provides services for protein expression and purification, assists with projects in designing strategies for high level expression of soluble proteins, provides vectors and strains. Offers clonning the gene of interest into expression vectors, rapid screening for optimal combinations of vectors, strains and expression conditions and producing protein of interest in E. coli, Pichia pastoris, mammalian and insect cells. Produces biomass at 1L to 10L scale using multiple bioreactor system for high cell density fermentation of bacteria and yeast cells and reusable bioreactor for cell culture. Proteins are then purified using standard techniques and chromatography systems. Quality control is routinely assessing protein identity, purity, stability and folding using set of different biochemical and biophysical methods.
Facility for protein crystallisation and X-Ray crystallography. Provides structural biology infrastructure and performs crystallization experiments.
Facility for light microscopy and flow cytometry. Users are instructed by staff in operation of hardware and software and, if necessary, are supported in acquisition, processing and quantitative evaluation of images.
System software used for analyzing dPCR data. If you have purchased QuantStudio Absolute Q Digital PCR system, you may download the system software. Software is available in Thermo Fisher Connect folder.
PCR System is plate based digital PCR platform powered by proprietary microfluidic array plate technology that enables all necessary steps for dPCR including compartmentalizing, thermal cycling and data acquisition to be conducted on single instrument. Uses nucleic acid quantification technique that allows absolute quantification without the need for standard curves. Bulk reaction mix is distributed or digitized into thousands of small independent reactions so that each micro-chamber contains either one or zero copies of the target. Statistical methods are then used to calculate the original concentrations based on the number of positive and negative micro-chambers.
Tapestri single-cell DNA sequencing platform provides both genotype and phenotype data from the same cell. Platform consists of instrument, DNA cartridge, which represents microfluidics device, and reagents. Cartridge is equipped with reservoirs that are used to load reagents required for automated cell processing. Pressure supplied by instrument drives reagents from reservoirs through microfluidic device and out to PCR collection tubes that are mounted below cartridge. Cartridge and tubes can be loaded and unloaded from instrument and disposed of after completion of workflow. User interacts with instrument via touch screen interface, which can be used to select programs, monitor status of running programs, and more.
Metapathways is an automated (meta)genomics annotation pipeline for predicting metabolic functions of given DNA sequences. It produces structured data products as pathway-genome databases with human-readable and machine-interpretable representations compatible with resources like PathwayTools and Metacyc from the Stanford Research Institute. A modular architecture, automated installation with Anaconda, and available containers on Quay.io maximize the accessibility, extensibility, and utility of Metapathways.