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Core offers imaging for diverse applications, including multi-color experiments, live sample imaging, protein colocalization, large sample tiling, and Z-stack 3D/4D imaging, as well as weak label detection. Provides expert guidance in microscopy and image analysis, training and support to advance research across various model organisms.
Software R package to perform feature specific quantile normalization. Designed to quantile normalize each feature in data set according to its corresponding feature in target distribution. This eliminates distribution based differences resulting from the use of different gene expression profiling platforms.
Software for evaluating, comparing and presenting real-time interaction data. Used for quantification of kinetics and affinity through curve fitting, with large number of binding models to choose from. Can extract experimental information from measurement, requiring minimal user input.
Core includes instrumentation for structural biology with focus on cryo-electron microscopy. Used for imaging ranging from atomic resolution to whole cells, with emphasis on linking structural and dynamics information with biological functions.
Software quality control tool for digital pathology slides. Used to identify and delineate slide artefacts and discover cohort-level outliers.
Software quality assurance and checking tool for quantitative assessment of magnetic resonance imaging and computed tomography data. Used for quality control of MR imaging data.
Software multi-modality post-processing suite for SPECT, CT, PET, MR, Optical and and Autoradiography imaging data.
Software Python package that plots data on cortical surface.
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Fully automated multi-channel peptide synthesizer equipped with a two arm pipetting robot for faster washing and dispensing of reagents. Parallel synthesizer for solid phase peptide synthesis. Standard system is configured with two reactor blocks with other reactor block options available including heating block kits and Tip reactor blocks.
System for image-guided radiation with software and advanced set of imaging modalities, including Cone-Beam CT, µCT and Bioluminescence (BLI). Focal irradiation system that mimics clinical radiotherapy and imaging.
Vitrification Robot is fully PC-controlled device for rapid cooling of aqueous samples. System offers semi-automated vitrification to provide fast, easy, and reproducible sample preparation for cryo-EM. Performs cryo-fixation process at constant physical and mechanical conditions like temperature, relative humidity, blotting conditions, and freezing velocity.
Leica CM1860 UV cryostat for high-quality cryosections with compact design, and user-friendly interface for optimal results.
Replidec: Replication Cycle Decipher for Phages. A software that predicts three phage replication cycles, including virulent, temperate, and chronic cycles in viral sequences, using Naïve Bayes classifier and alignment-based methods to improve prediction accuracy in metagenomic data.
Platform for genomic analysis. Open access online genomics datascience and discovery platform designed to assist the bio-medical researchers with limited to no Bioinformatics skills to perform data mining tasks in the omics field.
Software tool as GUI based Python program for reduction and analysis of small-angle X-ray solution scattering (SAXS) data.Small-angle scattering data reduction and analysis. Available on Windows, macOS (and OS X), and Linux.
This resource is no longer in service. Documented on September 19,2024. Web application to provide predicted protein circular dichroism spectra from multiple molecular dynamics-generated protein structures.
Web server for accurate protein secondary structure prediction and fold recognition from circular dichroism spectra.
Core provides irradiation services for investigators, including those whose primary interests are not in radiation biology, but who need this tool in support of other efforts, such immunosuppression of animals prior to stem cell transplantation through total body irradiation. Facility is equipped to perform moderate dose rate gamma irradiation (0.1-4 Gy/min) of cell cultures, tissue specimens or animals as well as low dose rate irradiation (0.05-0.3 Gy/hr) of cell cultures.
Provides immunologic and biological support for ongoing research projects and clinical trials. Services include measuring multiple cytokines in single assay, determining cytokine concentrations in various biological specimens and monitoring immune cell activation through investigative analytic procedures. Offers sample processing expertise for blood and tissue samples, including both plasma or serum and peripheral bloodmononuclear cells.