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The Neuropathology Core leads neuropathological analyses of brains donated by research registry participants of the Boston University Alzheimer's Disease Center. The Core works with the Clinical Core to carry out the Brain Tissue Donation Program, which provides brain tissue for analyses that will help to understand the underlying pathology of AD. The Core also works closely with the Data Management and Statistics Core to maintain a comprehensive computerized database of information resulting from neuropathological analyses. The Boston University Brain Bank of the Neuropathology Core documents neuropathological findings of Center research registry participants, but also of brain donors from important related BUSM studies such as the Framingham Heart Study and the Centenarian Study.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 9, 2022. A consumer health database that provides up-to-date information on diseases, conditions, injuries, drugs, supplements, treatment options, and healthy living, with a special focus on comparative effectiveness research from institutions around the world. PubMed Health includes * consumer guides summarizing comparative effectiveness research * fact sheets on diseases and conditions * information on drugs and supplements * encyclopedic overviews of health topics * links to external Web sites PubMed Health has a special focus on comparative effectiveness research, in particular that research which evaluates the available evidence of the benefits and harms of different treatment options for different groups of people. In Comparative Effectiveness Research, experts often synthesize the evidence from dozens, or even hundreds, of individual studies.

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• SciCrunch
• 16 years ago - by Anonymous

Software to create strand inheritance plots in data derived from the Strand-Seq sequencing protocol. The software is designed to be flexible with a range of species, and basic template folders can called to read in species-specific data.

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• SciCrunch
• 13 years ago - by Anonymous

Software that implements a Bayesian Analysis of Molecular Variance and different likelihood models for three different types of molecular data (including two models for high throughput sequence data).

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• SciCrunch
• 13 years ago - by Anonymous

Under the direction of Stella Somiari, Ph.D., the tissue bank at Windber Research Institute acquires and banks large numbers of high quality and well annotated normal and diseased tissue specimens. These specimens are obtained from fully informed and consented donors using Institutional Review Board (IRB) approved protocols and are accompanied by detailed clinical, family history and demographic information. The tissue bank has established Standard Operating Procedures (SOPs) for tissue acquisition, handling, processing, packaging and shipping. All collaborators at participating clinics/medical centers utilize these procedures to ensure that the integrity of the specimen is maintained. Tissue types in our collection include plasma, serum, tissue embedded in optimum cutting temperature (OCT), formalin fixed paraffin embedded, and flash frozen. We also isolate and bank tissue derived products such as DNA, RNA and protein for research. Very stringent SOPs are in place for the process of extraction of these tissue-derived products and for quality control/quality assurance (QA/QC). The WRI tissue bank currently has 5 isothermal freezers each with the capacity to store 36,000 specimens. For all specimens obtained from surgical procedures, routine histology is performed to obtain representative Hematoxylin and Eosin (H & E) stained sections for imaging/archiving. All H & E sections are imaged on the Trestle SL-50 imaging system and these images are available online to designated collaborative sites. A certified pathologist verifies all tissue specimens and WRI has telepathology capabilities, which can also be utilized for pathology verification when a second pathologist opinion is required to confirm specimen diagnosis. Other uses of the telepathology capabilities include the verification of Laser Capture Microdissection (LCM) sections (by pathologist) to ensure the correct areas are captured for research. The telepathology system at WRI is the Trestle Corporation's Medmicro system, which permits the pathologist to remotely view, navigate and share images at sub-micron resolution over standard internet connections in real-time.

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• SciCrunch
• 16 years ago - by Anonymous

Center for patient care, education and research on cancer. The institute focuses its research on prevention methods, early detection, treatment and finding cures.

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• SciCrunch
• 16 years ago - by Anonymous

International private stem cell storage bank to collect, assess and cryogenically store living tooth cells from deciduous baby teeth. Tooth cell banking is a safe, natural and completely noninvasive method of collecting and preserving valuable stem cells which could hold the key to your child's health. Simply enroll, send us your child's tooth when it falls out, and they'll do the rest. Stem cell treatment to repair or replace damaged tissues or organs is the cornerstone of future medical science. Children's milk teeth, (baby teeth) have been identified as a rich source of these stem cells and have the potential to treat some of the worst illnesses and diseases facing people today. Stem cells from teeth (mesenchymal stem cells) are different from those found in cord blood (hematopoietic stem cells). Cord blood cells can be used to treat blood disorders such as leukemia, but stem cells from teeth are different. Stem cells from teeth can be used to grow a range of tissues including bone, nerve, fat, muscle and cartilage and may one day be used to grow entire organs. It is widely believed that stem cells will be used to treat a wide variety of diseases and injuries within the next decade. Their UK facility is regulated by the Human Tissue Authority (HTA), and they hold a full license. They are also registered with the Food and Drug Administration (FDA) in the US. BioEDEN, Ltd is ISO 9001:2008 accredited by the British Assessment Bureau. When you enroll for the BioEDEN service, you will be offered the opportunity to consent to donate any excess cells. BioEDEN will provide these cells to leading academic and clinical research centers to help further the progression of this technology to useful clinical applications. BioEDEN will only provide cells to researchers that have full ethical approval for their research and will be guided by our Advisory team as to the most appropriate research to support. The cells will be donated in accordance with strict regulatory guidelines and anonymity of the donor will be strictly assured at all times. Donation of cells is an entirely opt in service. If you choose not to give consent to donate, BioEDEN will simply store the cells for your child.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. Flu Wikie is a topical portal on the flu. Major categories include health, Flu Symptoms, Avian Influenza, Swine Flu, Cold, Vaccination, Pandemic, Vitamin D, and Immune System. Many articles on topic are included.

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• SciCrunch
• 16 years ago - by Anonymous

A resource for information pertaining to methodologies, tools and technologies of gene expression. The website offers resources for sequence analysis, database services, and other technologies of gene expression and regulation.

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• SciCrunch
• 16 years ago - by Anonymous

A blog featuring articles on the brain, consciousness, cognitive science, psychology and neurology. This resource is in Russian.

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• SciCrunch
• 16 years ago - by Anonymous

A list of Wordpress plugins that are useful for authoring scientific papers. Listed plugins include BibTeX Importer, Link to Link, Broken Link Checker, and Contact Info Options, among many others.

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• SciCrunch
• 14 years ago - by Anonymous

A hosting site for the distributed version control systems (DVCS) Git and Mercurial. The service offering includes an issue tracker and wiki, as well as integration with a number of popular services such as Basecamp, Flowdock, and Twitter.

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• SciCrunch
• 12 years ago - by Anonymous

A pan-European scientific association to encourage research across the neurosciences and to translate new knowledge on fundamental disease mechanisms into new medicines and clinical applications. As an interdisciplinary forum for the science and treatment of disorders of the brain, they promote the communication and cross- fertilization of high-quality experimental and clinical research across the field of neuroscience. ECNP is a non-profit member-based association, independently governed and self-funded. ECNP is a public-interest-serving entity.

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• SciCrunch
• 12 years ago - by Anonymous

A database of neuroscience-related concepts that utilizes visualization tools for the purpose of research, education and knowledge discovery. The data comes from PubMed abstracts and an algorithm that assumes related terms will appear together. The topics can include computational modeling, behavioral functions and neurological degeneration.

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• SciCrunch
• 16 years ago - by Anonymous

A drug discovery company focused on small-molecule drugs targeting G-protein-coupled receptors (GPCRs), the largest family of druggable targets. Heptares creates new medicines targeting previously undruggable or challenging GPCRs, a superfamily of receptors linked to many diseases. They are pioneering a structure-based drug design approach to GPCRs, leveraging proprietary technologies for protein stabilization, structure determination, and fragment-based discovery. Their partners include Cubist, MorphoSys, AstraZeneca, MedImmune and Takeda. Their objective is to build a broad pipeline of novel medicines to transform the treatment of serious diseases, including Alzheimer's disease, schizophrenia, diabetes, ADHD and chronic migraine.

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• SciCrunch
• 12 years ago - by Anonymous

Software package to infer gene regulatory networks from time-series measurements. The algorithm is expected to be useful in reconstruction of small biological directed networks from time course data.

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• SciCrunch
• 13 years ago - by Anonymous

Project portal's database of protein-ligand data sets provided by pharmaceutical partners that provide atomic details of drug mechanisms that will be used to improve computer-aided drug-design methods and thus accelerate drug discovery. The project aims to help companies release the high-quality data they have generated, which has incredible value to researchers working to improve methods of computer-aided drug discovery. Everyone stands to benefit from the ability to develop new medications more quickly and inexpensively. What computational chemists globally are trying to do is to make faster, more accurate, more predictive programs to speed up the process. Part of their mission is to engage the community in these challenges to test newly developed predictive algorithms.

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• SciCrunch
• 12 years ago - by Anonymous

Portal devoted to aging relevant scientific data and resources.

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• SciCrunch
• 12 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 5,2025. A not-for-profit membership organization, supporting the Open PHACTS Discovery Platform: A sustainable, open, and interoperable information infrastructure for applied life science research and development. The foundation is the successor organization of the Open PHACTS project, and aims to ensure the sustainability of the Open PHACTS Discovery Platform infrastructure. OPF also acts as a hub for scientific research and development relevant to the life sciences, and serves as a forum for the scientific community, allowing idea exchange between the pharmaceutical industry, academia and SMEs. OPF is a UK-based not-for-profit membership organization, but operates in an international commercial environment.

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• SciCrunch
• 12 years ago - by Anonymous

The UK's professional body for chemical scientists, supporting and representing members and bringing together chemical scientists from all over the world. This not-for-profit organisation has an international publishing business and their activities span education, conferences, science policy and the promotion of chemistry to the public. They have offices in Europe, Asia, North America and South America.

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• SciCrunch
• 12 years ago - by Anonymous