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Laser diffraction instrument for particle size determination in liquid and dry dispersion. Sample size range: 10 nm to 3.5 mm. Two solid state lasers, 830 nm and 450 nm.
Cellimage Mini is a compact real-time live-cell imaging system developed and manufactured by ReadCells Scientific. It is designed for long-term time-lapse dynamic observation of living cells, including intracellular calcium flux recording, tumor spheroid; organoid 3D growth tracking, cell migration, apoptosis and pharmacodynamic screening. Equipped with multi-channel fluorescence excitation modules, the system supports continuous non-invasive real-time monitoring under physiological culture environment, widely used in stem cell research, oncology, cardiovascular pharmacology and cell biology experiments.
Core provides infrastructure (A1 and A2 zoned) and technical expertise for standardized husbandry, breeding, experimental use of rodent and health monitoring (SPF and SOPF zones) in compliance with regulatory and ethical guidelines. The platform offers technical services such as Surgery on brain and spinal cord, Behavioral tests (anxiety, depression, cognition, motor/locomotor and visual parameters, spontaneous activity, USV recording etc… ), embryo transfer. Training and technical support are available for rodent handling, experimental design, and data reproducibility.
Web browser-based collection of tools for PCR primer design, Sanger sequencing primer design, primer binding checks, restriction site analysis, reverse complement generation, ORF and protein translation, codon optimization, DNA ligation calculations, molarity calculations, dilution calculations, and multi-solute solution recipe preparation. The tools run in the browser and are intended to help researchers perform common sequence checks and lab calculations quickly without requiring logins or server-side sequence upload.
Software pipeline for segmenting faba bean seed images and extracting shape, size, and color features to CSV.
Core provides services in design, construction, and production of custom research grade viral vectors for biomedical research including Adeno-associated viral (AAV) vectors, Retroviral vectors (MLV-based), Lentiviral vectors (LV), Virus-Like Particles (VLPs / Nanoblades).
Compact, automated hematology analyzer used primarily in physician offices, satellite clinics, and small hospital labs to perform Complete Blood Counts and 3-part white blood cell differentials.
Software toolbox for estimation of MR signal fraction of brain cell bodies (of all cell types, from neurons to glia, namely soma) and cell projections (of all cell types, from dentrites and myelinated axons to glial processes, namely neurties ) as well as apparent MR cell body radius and intraneurite and extracellular apparent diffusivities from a suitable diffusion-weighted MRI acquisition using Machine Learning.
Core can assist investigators in all aspects of rodent behavioral testing including the design and execution as well as the data analysis and interpretation. Facility is equipped to perform behavioral tests to thoroughly phenotype overall motor and sensory function of rats and mice as well as phenotype specific behaviors that are of interest to the investigators (learning and memory, motor function, place/fear conditioning, pain/analgesia, and anxiety-related behaviors).
Microscopy core managed by Cardiovascular Research Center. Operates as a teach and train service for confocal, slide scanning and general widefield fluorescence imaging.
Flow Cytometry facility provides instrumentation and expertise for cell sorting and analysis.Offers both full-service and self-service facilities, with support and training, as well as cutting-edge research instruments and software resources.
First translational medical research institute dedicated to translating scientific discoveries into applications for medical practice. Australian-first initiative of bench to bedside medical research.
Fully automated spatial proteomics instrument designed to visualize and analyze hundreds of proteins and RNAs within a single tissue section. It maps exactly where cells are and how they interact.
Core provides support for research teams using non-human primate models in scientific projects. It combines specialized biomedical infrastructure, neuroscience expertise, regulatory guidance and qualified technical staff to ensure the housing, monitoring, handling and experimental use of monkeys in accordance with ethical and regulatory standards. It offers technical support for experimental procedures (A2 facility, several imaging techniques), behavioral training, and neurophysiological investigations as well as gene and cell therapy projects (in collaboration with PBI’s TIDU GENOV unit).
Open-source ensemble platform for in silico Phase I and Phase II metabolite prediction with High-Resolution Mass Spectrometry (HRMS) target list generation. Used for Metabolite Identification (MetID) predictions and soft spot analysis.
Software R package for identifying and ranking influential nodes in biological and other complex networks. Implements the Integrated Value of Influence (IVI), Experimental data-based Integrative Ranking (ExIR), SIRIR, and numerous network centrality measures, enabling network topology analysis, influential node detection, feature prioritization, and candidate biomarker discovery. Provides functions for network reconstruction, centrality assessment, visualization, and analysis of relationships between centrality measures. Used for identification and classification of the most influential nodes.
Software R package to generate balancing weights for causal effect estimation in observational studies with binary, multi-category, or continuous point or longitudinal treatments by easing and extending the functionality of several R packages and providing in-house estimation methods. Used for propensity score weighting.
System equipped with DNP (Dynamic Nuclear Polarization) used primarily to dramatically boost the sensitivity of nuclear magnetic resonance (NMR) spectroscopy.It allows researchers to study complex molecular structures, materials, and biological systems that are normally difficult or impossible to observe. Console: Avance III HD; Magnet: Ascend; Field Strength:600 MHz Wide-bore; Software: TopSpin 3.8 on Alma 9.4; Probe: 3.2mm HCN LTMAS for DNP; 3.2mm HX LTMAS for DNP; 1.3mm HCN very-fast MAS.
Highly advanced system used by researchers in chemistry, biology, and materials science to determine the molecular structure, dynamics, and interactions of chemical compounds and biomolecules. Console: Avance III HD; Magnet: Ascend; Field Strength: 600 MHz, Software: TopSpin 3.7 on Windows 10; Probe: 5mm Broadband Observe (BBFO) "Smart" solution iProbe with Z-Gradients.
High-field, ultra-sensitive system used by researchers for deep structural, dynamic, and metabolic analyses of complex molecules. Console: Avance III HD; Magnet: Aeon; Field Strength: 800 MHz Wide-bore; Software: TopSpin 3.8 on Alma 9.4; Probe: 3.2mm Efree HCN MAS; 3.2mm HXY MAS; 1.9mm HCN MAS; 1.3mm HCN MAS; 0.7mm HCND ultra-fast MAS.