We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software application provides researchers with scores for tumor purity, level of stromal cells present, and infiltration level of immune cells in tumor tissues based on expression data.
Real time PCR commercially available kit
Semantic store of detailed, formal knowledge about ANS connectivity between the central nervous system and end organs. As key component of NIH SPARC program, SCKAN enables integration, discovery, and querying of ANS connectivity across multiple scales.
Graph database supporting Blueprints and RDF/SPARQL APIs. Supports up to 50 Billion edges on single machine. It is in production use for Fortune 500 customers such as EMC, Autodesk, and many others. It supports key Precision Medicine applications and has wide-spread usage for life science applications. Used to support Cyber analytics in commercial and government applications.
Software package of open-source graph visualization tools. Provides also libraries for software applications to use the tools. Provides a way of representing structural information as diagrams of abstract graphs and networks.
DNA extraction kit
Used in the ddPCR reaction
Used in the ddPCR reaction
Web-based open-source data visualization software made in JavaScript. Aims at providing missing link between spreadsheet applications (e.g. Microsoft Excel, Apple Numbers, OpenRefine) and vector graphics editors (e.g. Adobe Illustrator, Inkscape, Figma).
Web application as JavaScript-based intuitive search interface to explore the SPARC Connectivity Knowledgebase of the Autonomic Nervous System.
This digital PCR supermix delivers maximum PCR efficiency and sensitivity for the amplification and detection of DNA targets using hydrolysis probe–based assays.
ddPCR Analysis tool
Software toolkit for detection of allele-specific RNA N6-methyladenosine modifications.
Core offers quantitative and qualitative proteomics services using LC-MS/MS technologies. Servies include sample preparation from harvested cell pellets, elutions post-enrichment or purification, or gel bands through data acquisition, quantification, and statistical analysis.
Guidelines for accessing and sharing data collected by the All of Us Research Program. It aims to ensure responsible data use while promoting transparency and collaboration in research to advance precision medicine.
Software tool for detecting transposon insertions using short-read whole-genome sequencing data. Used to detect germline transposon insertions, estimate number of uninherited/somatic transposon insertions by removing artificial insertion introduced by chimeric reads.
Software package to facilitate microbiome exploration and ensuring nice plotting.
This technology relies on newly described chemical modifications that allow site-specific and multiple-site conjugation of a wide assortment of molecules on both the termini and internal sites of Cas9, creating a platform for endowing Cas9 with diverse functions. Using this platform, Cas9 can be modified to more precisely incorporate exogenously supplied single-stranded oligonucleotide donor (ssODN) at the DNA break site. We demonstrate that the multiple-site conjugation of ssODN to Cas9 significantly increases the efficiency of precision genome editing, and such a platform is compatible with ssODNs of diverse lengths.
Microfluidic systems including housing configured to receive cartridge, housing including channels for loading one or more biological cells within wells of the cartridge. Three-dimensional scaffolds, devices, and systems comprising such scaffolds that mimic the in vivo structure, physical properties, and protein composition of extracellular matrix surrounding pancreatic islet cells and adipocytes, with use for, e.g., in vitro drug screening and/or toxicity assays, disease modeling, and therapeutic applications. The cartridge including a plurality of wells for receiving one or more biological cells. The microfluidic systems include a structure with channels for introducing a medium into the housing and through channels the cartridge.