We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software tool for batched microscopy image contrast adjustment and pseudocoloring in Matlab.
Software Python library for navigation, visualisation, and analysis of whole-brain quantification data. Integrated suite for multi-marker automated segmentation, whole-brain statistical analysis, and data visualisation. Used for quantitative multi-marker image analysis of whole-brain registered datasets.
Software package for optimal matching in R. Distance based bipartite matching using minimum cost flow, oriented to matching of treatment and control groups in observational studies. Routines are provided to generate distances from generalised linear models (propensity score matching), formulas giving variables on which to limit matched distances, stratified or exact matching directives, or calipers, alone or in combination.
Softawer framework for de novo chromosome-by-chromosome assembly with long reads. Long-reads gap-free chromosome-scale assembler.
Core offers services including molecular modeling of proteins and nucleic acids, virtual drug screening, computational biophysics.
Software MATLAB package for analyzing and categorizing behaviors using pose estimation data. Integrates semi-automatic labeling with machine learning, specifically Long Short-Term Memory neural networks, to classify behavioral "syllables” (distinct, repeatable behaviors). Combinatory approach of semi-automatic labeling and long short-term memory to classify behavioral syllables.
Software suite of scripts to detect and analyse de novo variants from multi-sample vcf.
Software tool for selecting predictors such as bacteria for any continuous environmental variable such as pH, illness measurements, diseases index, etc. Sparse compositional microbiome-predictors selection and prediction of continuous environmental factors. Used for unlocking prediction of continuous environmental variables based on microbiome.
Electron Microscopy Center at USC is core facility providing all levels of technical support and consultation in area of light microscopy, electron microscopy, and elemental analysis. Provides microscopy and specimen preparation services for biological and materials science research. Offers training and access to all microscopes and ancillary equipmen.
Core offers resources and solutions for conducting genomics, transcriptomics, epigenomics and functional genomics projects. We work with researchers to determine project goals and design custom solutions. We assist at all stages of the project, from support in grant development to generation of publication-quality data. Services include Consultations, Bioinformatics, Nucleic Acids purification, quantification and QC DNA Sequencing (SANGER and NGS), Library Constructions for NGS applications,Microarray Hybridization, Real Time PCR, Custom epigenomics applications, Lentiviral vectors and lentiviruses construction and production, CRIPR-CAS9sgRNAs and RNAi/shRNAs knockdown of individual genes and functional screening of sgRNA and shRNA libraries for target identification.
Provides support to experiments that use mouse models to elucidate mechanisms of normal physiology and disease processes, and to develop and test novel agents and therapies to treat diseases. Provides centralized facililty for breeding, genotyping, maintaining colonies, conducting animal experiments, collecting tissues, analyzing experimental results, and training personnel in proper procedures for conducting animal experiments. Core also hosts germ-free mouse facility that works with PI's to produce, distribute, and conduct experiments in germ-free and gnotobiotic mouse models. MEF/GCF offers expertise with genetic, induced, or orthotopic models of disease and coordinates with other USC Cores with respect tissue processing and preparation for various types of analyses.
Facility provides quantitative compositional information from top atomic layers of sample surface for the elements lithium to uranium. Core can also obtain information regarding chemical states of any elements present. This facility houses Kratos AXIS Supera+ Spectrometer Unit.
Software lightweight GIMP plug-in to alllow for computer vision-assisted image annotation using GIMP selection toolbox.
Deep learning phenotyping of Arabidopsis fruit morphology. Deep learning model weights and inference code to detect Arabidopsis thaliana siliques in scans of stem material. Phenotyping code to extract length, diameter area and volume metrics of siliques from model outputs.
Updatable online database of mammal taxonomic and biodiversity information hosted by American Society of Mammalogists. Provides information on species-level and higher taxonomic changes, thereby promoting more rigorous study of mammalian biodiversity worldwide. The initial objective has been to aggregate, curate, and compile, new citations on species descriptions and taxonomic revisions into regular releases that are downloadable in comma-delimited format. Downstream goals include expanded hosting of ecological, trait, and taxonomic data.
Thermal Cycler is benchtop PCR machine which features 5-inch color touchscreen for easy control and is also accessible through Thermo Fisher Connect , giving you the freedom to design and securely upload your methods from any mobile device or desktop computer. Designed for amplification of nucleic acids using Polymerase Chain Reaction process. User interface includes touchscreen with graphical display that shows time, status, and temperature for each run. Touchscreen keypad allows to enter information into fields on display screen.
Software tool to discern whether peptide will be recognized by HLA as epitope. Capable of directly identifying peptides as epitopes without the need for inputting HLA alleles. Hybrid transformer model for peptide-HLA epitope detection.
Core answers research questions in any scientific, medical or industrial discipline through capture, processing, image analysis, training and sample preparation services for microscopy. Provides technical and scientific support in advanced microscopy and image processing and analysis.
Core offers Next Generation Sequencing services using Element Biosciences AVITI short read sequencer, PacBio Revio and Oxford Nanopore Promethion/GridIon long read sequencers along with 10X Genomics X, 10X Genomics Visium CytAssist, and 10X Xenium Analyzer single cell/spatial technologies.
Research institute in Esch-sur-Alzette, Luxembourg to study brain and its diseases. Collaboration between biologists, medical and computer scientists, physicists, engineers as well as mathematicians offers new insights into complex biological mechanisms and disease processes, with the aim of developing new tools for diagnostics, prevention, and therapy. LCSB has established strategic partnerships with scientific partners worldwide and with all major biomedical research units in Luxembourg. Carries out collaborative projects with hospitals and research-oriented companies, accelerating translation of fundamental research results into clinical applications.