We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Desktop software suite targeted to curators and experimentalists that assists in the reporting and local management of experimental metadata, engages with minimum information checklists and ontologies and formats studies for submission to international public repositories. The ISA software suite is the product of an ongoing collaboration between various research and service groups from diverse life science domains. It represents an opportunity for the wider research community to start taking data management into their own hands by supporting graduated adherence to community standards and the efficient curation of experimental metadata at source, shielded from underlying complexities. The software suite is comprised of several platform-independent Java-based software components for local use, including a relational database, built around the ISA-Tab format. The components work both as stand-alone applications and as a unified system.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented April 7, 2018.<br/><br/>Online portal and searchable database with resources for the greater scientific community such as zoological records, nomenclature guides, and relevant scientific news stories and websites.
WIRM is an innovative software toolkit that allows the creation of web applications that facilitate the acquisition, integration, and dissemination of multimedia biomedical data over the web, thereby reducing the cost of knowledge sharing. WIRM reduces the complexity of building custom biomedical web applications and it's visual modeling tools enable domain experts to describe the structure of their knowledge, from which WIRM automatically generates full-featured, customizable content management systems. WIRM is a Perl-based application server that provides a high-level programming environment for developing web information systems. WIRM consists of an object-relational database and a suite of Perl interfaces for visualizing, integrating and analyzing heterogeneous multimedia data. WIRM provides facilities for creating context-sensitive views over a multimedia database, allowing developers to rapidly build dynamic web sites that adapt their content and presentation to multiple classes of end-users. WIRM was developed by Rex Jakobovits as part of his PhD dissertation at the University of Washington Computer Science department, under the guidance of Dr. James F. Brinkley of the Department of Biological Structure. The system was generalized from work funded by NIH SBIR grant R43-MH61277-01 and Human Brain Project grant DC/LM02310.
The Image Repository contains a collection of images produced by the research of John Clark's Eye Lab. Experiments include: Irradiated CP49 KO and wildtype, Hypothesis: CP49 KO mice will be more sensitive to X-irradiation than controls Huntington Mice Cataract ID, Hypothesis: Individuals can be identified by the pattern of their cataract. Alpha-Synuclein Mice, Hypothesis: Mice transgenic for the EGFP-tagged, mutant and WT strains of human alpha-synuclein gene, will provide a model for the testing of drugs on aggregation of the protein. alpha B Crystallin/SPARC DKO, Hypothesis: The absence of the chaperone protein, alpha B-Crystallin, causes a greater intensity and earlier onset in the opacifying effects of an absence of the matricellular protein, SPARC. Survey of SPARC KO and WT Survey of SPARC KO and WT Mice The repository is being built through a collaboration between the University of Washington's Department of Biological Structure, led by John Clark, and the Structural Informatics Group, led by Jim Brinkley. As an aim of the Biomedical Information Sciences Technology Initiative (BISTI), members of the Structural Informatics Group have been talking with biomedical researchers to find out their informatics needs. Tools such as this repository are being created in response to those needs. This web tool allows the researchers to add their images to a repository facilitating the organization and management of their data.
Non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids. Facilitates archiving and distributing DNA-based research reagents and associated data to scientists worldwide. Repository contains over 65,000 plasmids, including special collections on CRISPR, fluorescent proteins, and ready-to-use viral preparations. There is no cost for scientists to deposit plasmids, which saves time and money associated with shipping plasmids themselves. All plasmids are fully sequenced for validation and sequencing data is openly available. We handle the appropriate Material Transfer Agreements (MTA) with institutions, facilitating open exchange and offering intellectual property and liability protection for depositing scientists. Furthermore, we curate free educational resources for the scientific community including a blog, eBooks, video protocols, and detailed molecular biology resources.
Database of genetic and molecular biological information about Candida albicans. Contains information about genes and proteins, descriptions and classifications of their biological roles, molecular functions, and subcellular localizations, gene, protein, and chromosome sequence information, tools for analysis and comparison of sequences and links to literature information. Each CGD gene or open reading frame has an individual Locus Page. Genetic loci that are not tied to DNA sequence also have Locus Pages. Provides Gene Ontology, GO, to all its users. Three ontologies that comprise GO (Molecular Function, Cellular Component, and Biological Process) are used by multiple databases to annotate gene products, so that this common vocabulary can be used to compare gene products across species. Development of ontologies is ongoing in order to incorporate new information. Data submissions are welcome.
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. The World Parkinson's Disease Association is an alliance of members from all over the world who have come together to share information about Parkinson's disease. In order to further Parkinson's research and better the condition of those diagnosed with the disease, the Association: establishes computerized connections; takes part in and/or finances research activities; urges pharmaceutical companies and government institutions of the various countries to support the guidelines recommended by the associations of Parkinson's patients; and coordinates and promotes interchange of information among its members with the aim of solving problems of mutual interest.
A nonprofit organization dedicated to providing an international forum for the latest scientific discoveries, medical practices and caregiver initiatives related to Parkinson's disease. It hosts the annual World Parkinson Congress, an event which focuses on bringing physicians, scientists, allied health professionals, caregivers and people diagnosed with Parkinson's disease together, in order to create a global dialogue that will help expedite treatment practices and the discovery of a cure .
This popular web resource includes over 1900 images along with text, tutorials, laboratory exercises, and examination items for self-assessment that demonstrate gross and microscopic pathologic findings associated with human disease conditions. Content includes pathology cases (surgical pathology, autopsy, cytopathology, forensic pathology, clinical pathology) at the University of Utah Health Sciences Center and affiliated hospitals and laboratories, and from contributors at other institutions worldwide. The content at this web site will assist a medical student in achievement of an important goal: passing step 1 of the USMLE examination required to become licensed as a physician. This site was conceived from the necessity to create useful multimedia teaching resources for medical students at the University of Utah for use in the pathology courses given in the second year of the curriculum.
An open-source software pipeline for Affymetrix Axiom genotyping workflow.
Software package that facilitates creation and verification of pedigrees within large genealogies. The pedigrees are produced as files in LINKAGE format ready for linkage analysis and for drawing with a variety of drawing programs, such as PEDDRAW and cranefoot.
Software tool for the automatic association analysis among the variation of the patient genomes and the clinical conditions of patients, i.e. the different response to drugs. The system allows: (i) to automatize the workflow of analysis of DMET (drug metabolism enzymes and transporters)-SNP (Single Nucleotide Polymorphism) data avoiding the use of multiple tools; (ii) the automatic annotation of DMET-SNP data and the search in existing databases of SNPs (e.g. dbSNP), (iii) the association of SNP with pathway through the search in PharmaKGB, a major knowledge base for pharmacogenomic studies. It has a simple graphical user interface that allows users (doctors/biologists) to upload and analyze DMET files produced by Affymetrix DMET-Console in an interactive way.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 18, 2016. TheBrainMatters.org is a comprehensive resource for the public that provides information on on more than 250 neurologic disorders . This site combines important information from such credible sources as the American Academy of Neurology and the National Institute of Neurological Disorders and Stroke websites into one clean, organized, and user-friendly site designed specifically for users to become better informed about neurologic disorders.
Database to retrieve and compare gene expression patterns between animal species. Bgee first maps heterogeneous expression data (currently bulk RNA-Seq, scRNA-Seq, Affymetrix, in situ hybridization, and EST data) to anatomy and development of different species. Bgee is based exclusively on curated healthy wild-type expression data (e.g., no gene knock-out, no treatment, no disease), to provide a comparable reference of gene expression.
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. A collaborative initiative of Parkinson's organizations dedicated to increasing education and awareness about clinical research. PDtrials provides up-to-date information on Parkinson's disease trials currently enrolling participants in the U.S. and Canada, as well as information about Parkinson's studies for people living with PD, their families and caregivers. Researchers can list their own trials on the PDtrials website. Patients can browse trial listings by type, location, symptom, or keyword.
Software package for a DNA assembly program designed for de novo assembly of 25-40mer input fragments and deep sequence coverage.
A U.S. organization which funds Parkinson39;s disease research and provides materials and services to patients. PDF funds research through: research centers at major universities; early-career investigators that devote their talents to the study of Parkinsons; funding independent investigators through the International Research Grants Program; and collaboration with other organizations on innovative projects.
A consortium created to support the provision of optimal care and education for veterans diagnosed with Parkinson's disease and related movement disorders through professional education, collaboration and advocacy.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 06, 2013. Per the associated paper, Aguirre GK (2012) FIASCO, VoxBo, and MEDx: behind the code. Neuroimage 62: 765-7, the MedX software was discontinued. The website itself however, looks like you can still buy it (website last updated 2004). Highly optimized, portable, commercial software for the visualization, processing, and analysis of medical images. The packages include: SPM '99, FSL, DICOM Import/Export, ABLe, Functional Data Simulator. Designed especially for medical imaging researchers and system developers, MEDx brings multi-modality, multi-dimensional image processing functionality to the medical imaging research community. With MEDx, users display images and control menus using the industry-standard XWindow display system and Tcl/Tk interface language. MEDx transforms your computer into a powerful image processing workstation that displays, analyzes, and processes your medical image data in a myriad of innovative ways.
The Parkinsons Disease Society funds research, offers educational information, advice, and support from medical professionals, and runs campaigns with the goal of offering support, raising money, and finding a cure for Parkinsons disease. In addition to funding research, the Society offers a Helpline to support those suffering from Parkinsons and their caregivers, and also offers a range educational materials. The Society has a network of over 330 branches and support groups located across the UK. Additionally, the Society campaigns for and influences government policy and the development of high-quality services at a local and national level.