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THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. It has been incorporated with the LBIH Biobank. The Liverpool Tissue Bank (LTB) collects biological samples (tissue surplus to diagnostic requirement and blood) from patients undergoing surgery or biopsy procedure for the treatment and diagnosis of a wide variety of medical conditions. The main focus of the LTB is collecting samples from patients where cancer is a confirmed or likely diagnosis. These samples are banked to provide an invaluable resource for research groups investigating the molecular mechanisms involved in a range of medical conditions with the aim of devising new treatments and therapies. The Liverpool Tissue Bank (LTB) was formerly known as the Cancer Tissue Bank Research Centre (CTBRC) and changed to the LTB in late 2009. The Tissue Bank was established in 1991 from a charitable donation by the Candis Club, the charitable arm of Candis Magazine. It is a University of Liverpool resource located within the Department of Pathology, School of Cancer Studies. The LTB operates a cost recovery scheme where a charge is made to researchers to cover the costs involved in the collection, storage and processing of biosamples.

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• SciCrunch
• 16 years ago - by Anonymous

The Parkinson's Disease Mouse Model Resource (PDMMR) is funded by the Michael J Fox Foundation to provide genetically engineered mice and information useful for their selection and use. The resource also serves as an archive of genetically stable mouse models. The Repository distributes Parkinson's disease models that are useful for the study of the basic pathophysiology of PD, and for testing new therapies. Also available are research tool strains including transgenics that express marker genes in affected brain regions, and strains with systems for regulating gene expression (e.g. Cre recombinase and tet-inducible promoters) in specific types of neurons.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. Stem cell research, particularly human embryonic stem cell (hESC) research, holds tremendous promise to discover therapeutic options and perhaps cures for insidious diseases such as cancer, juvenile diabetes, Alzheimer's and Parkinson's. The Massachusetts Human Stem Cell Bank provides the biomedical research community with expertly maintained human ES (hES) and reprogrammed (iPS) cell lines to facilitate studies into the properties and potential therapeutic applications of pluripotent stem cells. The Bank cultures, characterizes and distributes quality controlled hES and iPS cell lines derived in Massachusetts and beyond. The Bank is a 15,000 square foot facility that contains research and training space for visiting investigators. In addition, the Education and Training division provides technical training and programs to educate the community.

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• SciCrunch
• 16 years ago - by Anonymous

A freely available online personalized cancer medicine knowledge resource for physicians, patients, caregivers and researchers that gives up-to-date information on what mutations make cancers grow and related therapeutic implications, including available clinical trials. It is a one-stop tool that matches tumor mutations to therapies, making information accessible and convenient for busy clinicians.

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• SciCrunch
• 13 years ago - by Anonymous

Platform for storing, finding and accessing data that provides a service for data centres to mint DOIs and store associated metadata. Their goals are to establish easier access to scientific research data on the Internet, increase acceptance of research data as legitimate, citable contributions to the scientific record and support data archiving that will permit results to be verified and re-purposed for future study. DataCite is global, with member institutions offering services and advice directly where they are needed by the researchers. While datasets are shared and accessed globally, researchers work within national funding and organizational frameworks. It therefore operates globally, with national representation. The DataCite Metadata Scheme is a list of core metadata properties chosen for the accurate and consistent identification of data for citation and retrieval purposes, along with recommended use instructions.

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• SciCrunch
• 16 years ago - by Anonymous

Sunnybrook Research Institute''s tumour bank provides a mechanism for the optimal collection, storage and distribution of human tissue for investigative purposes. We collect both freshly frozen and formalin-fixed paraffin-embedded tumour and normal samples, retrospectively and prospectively (informed consent and confidential consent is obtained from patients before sample collection). We offer the 1. Distribution of tissue and data to interested investigators after approval from the institutional research ethics board and 2. Collaboration with various research investigators. Our mandate is to design, implement and manage the structures and processes to ensure the timely provision of tissue samples and associated data. We are currently building bank on four disease sites: breast, prostate, colorectal, gynecological. We are also creating and maintaining a database with a tissue tracking and inventory system, using TissueMetrix software.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESORUCE IS NO LONGER IN SERVICE. Documented on April 27,2023. CCLG is an association of healthcare professionals involved in the treatment and care of children and younger teenagers with cancer, and underpins all the activity in pediatric oncology in the British Isles. CCLG is committed to research and development in the treatment of cancer in this age group, the ultimate goal of which is to maximize cure while minimizing the early and late side effects of treatment. Provision of information for patients and families is a core activity. The Children''s Cancer and Leukaemia Group was formed in 2006 as a result of the merger of the UK Children''s Cancer Study Group and the UK Childhood Leukaemia Working Party, both of which had been in existence since the 1970s.

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• SciCrunch
• 16 years ago - by Anonymous

A biorepository is a place where investigators can deposit and store biological material, in this case samples derived from patients. Moreover, the Genomic Medicine Institute (GMI) takes this basic concept and elevates it to make the Genomic Medicine Biorepository (GMB) a full-service processing and banking laboratory that serves as the foundation for evidence-based research for the GMI, the Cleveland Clinic, and our collaborators. The process relies on a team of multi-disciplinary professionals coordinating their efforts in order to streamline medical research. This begins with dedicated physicians and genetic counselors identifying individuals with specific medical conditions indicating the possibility of genetic involvement. Once identified, biological material (e.g. blood, tissue, or saliva) is collected under the care of the patient''s doctor or by our clinicians and sent to the GMB. Once in the lab, the patient and their samples are assigned a unique identifier (to protect the patient''s personal information) and logged into a central database. This unique identifier accompanies all samples processed and banked for that individual. The specimens are then processed into research-relevant samples using proven laboratory techniques and state-of-the-art quality control practices. These samples include the isolation of DNA and RNA from white blood cells for genetic studies; collection of plasma for proteomic studies; and initiated immortalized cell lines from lymphocytes for in-vitro studies and biochemical research. These cell lines are able to be indefinitely stored in cryogenic suspension and are invaluable as a renewable resource for genetic and biochemical research. The GMB also processes genetic material from various tissues (both fresh and archived). Charis Eng, MD, PhD, Chair and Director of the GMI, has been the faculty oversight person of a human biorepository for the last eight years. Since then, our biorepository has received, cataloged, processed, and banked, in excess of 25,000 specimens. These samples are of numerous tissue types from patients and their family members located all over the world. Our biorepository has managed samples that have resulted in more than 150 original peer reviewed articles and greater than $25 million total direct costs in extramural funding over the last four years alone.

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• SciCrunch
• 16 years ago - by Anonymous

This is a facility for UK-based research into leukemia and other related disorders. The Bank contains viable cells and DNA from children diagnosed with acute leukemia. (diagnostic, treatment and relapse samples) and also HLA- typed normal cord blood donations. Samples can only be obtained from the Cell Bank for approved peer-reviewed and fully costed research projects. To view further information about the Cell Bank, or for instruction on how to apply for samples, please register.

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• SciCrunch
• 16 years ago - by Anonymous

The Center for Interdisciplinary Brain Sciences Research (CIBSR) at the Stanford University School of Medicine is dedicated to research that will improve the lives and well-being of individuals with disorders of the brain and improve knowledge of healthy brain and behavioral development. CIBSR research staff are dedicated to identifying biological and environmental risk factors, understanding disease pathophysiology and developmental outcomes, and developing new treatments for neurodevelopmental, neurogenetic and neuropsychiatric disorders of childhood onset. Our research studies are truly multi/interdisciplinary as they bring together experts from the fields of psychiatry, neurology, psychology, computer science, biostatistics and genetics to explore and seek answers for complex questions related to brain-behavior relationships. Active research at CIBSR includes: * Mutlimodal imaging of the brain utilizing anatomical and functional magnetic resonance imaging (MRI), diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS). * Behavioral, cognitive, and physiological assessment to address questions concerning the influence of biological and environmental factors on outcome. * The development of new biological and cognitive-behavioral treatments. * Development of brain image analysis methods and software.

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• SciCrunch
• 17 years ago - by Anonymous

Curated knowledegbase of protein structures that are reported to be involved in 3-dimensional domain swapping. 3DSwap provides literature curated information and structure related information about 3D domain swapping in proteins. Information about swapping, hinge region, swapped region, extent of swapping, etc. are extracted from original research publications after extensive literature curation.

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• SciCrunch
• 16 years ago - by Anonymous

International Mental Health Research Organization (IMHRO) is a 501(c)3 organization committed to raising awareness and funding research to find preventions and cures for schizophrenia, depression and bipolar disorder within a generation. We are families and individuals whose lives have been touched by these brain diseasesand who have seen how far mental health research has come in the last decade. Contributors to IMHRO have played a major part. The $135 million they have helped to raise has funded stunning scientific discoveries to help people now and tomorrow.

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• SciCrunch
• 16 years ago - by Anonymous

Portal to research centers and core facilities specifically support obesity research and better understand the relationship between health and nutrition.

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• SciCrunch
• 12 years ago - by Anonymous

Framework for discovery of, and interoperability between, distributed data and analytical resources. It combines GET/POST-based Web Services with standards from the W3C Semantic Web initiative. The objective is to make it easy for data and analytical tool providers to make their resources available on the Semantic Web with minimal disruption to their usual practices. It simply defines an open set of best-practices and conventions, within the spectrum of existing standards, that allow for a high degree of semantic discoverability and interoperability between participating services.

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• SciCrunch
• 16 years ago - by Anonymous

Repository for all research outputs from across all fields of science in any file format as well as both positive and negative results. They assign all publicly available uploads a Digital Object Identifier (DOI) to make the upload easily and uniquely citeable. They further support harvesting of all content via the OAI-PMH protocol. They promote peer-reviewed openly accessible research, and curate uploads. ZENODO allows users to create their own collection and accept or reject all uploads to it. They allow for uploading under a multitude of different licenses and access levels.

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• SciCrunch
• 12 years ago - by Anonymous

A partnership of academic and research institutions, offering a collection of millions of titles digitized from libraries around the world. Their goals are: * To build a reliable and increasingly comprehensive digital archive of library materials converted from print that is co-owned and managed by a number of academic institutions. * To dramatically improve access to these materials in ways that, first and foremost, meet the needs of the co-owning institutions. * To help preserve these important human records by creating reliable and accessible electronic representations. * To enable the digital archive to be accessible to persons who have print disabilities. * To stimulate redoubled efforts to coordinate shared storage strategies among libraries, thus reducing long-term capital and operating costs of libraries associated with the storage and care of print collections. * To create and sustain this public good in a way that mitigates the problem of free-riders. * To create a technical framework that is simultaneously responsive to members through the centralized creation of functionality and sufficiently open to the creation of tools and services not created by the central organization.

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• SciCrunch
• 12 years ago - by Anonymous

Committee to foster strategic thinking about how to more rigorously manage the transition from analog to digital in higher education to ensure the programmatic, concerted, and efficient development of large-scale projects that, if built as coherent elements of an emerging digital environment, will significantly enhance scholarly productivity and enrich teaching. The Committee will produce a blueprint for this new environment that is cost effective and sustainable by focusing on the following activities: research and analysis of key large projects and the technology requisite for their correlation; business plans necessary for a coherent, sustainable digital ecology of enormous scale in service to education and the public good; and return on investment, that is, the benefits and transformational aspects of such an undertaking.

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• SciCrunch
• 12 years ago - by Anonymous

A wiki knowledge base for the life sciences that combines the collaborative and largely altruistic possibilities of wikis with explicit authorship. Authors are provided credit even while the knowledge can evolve via continual revision and traditional peer review into a rigorous scientific tool.

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• SciCrunch
• 16 years ago - by Anonymous

A higher education and research community initiative to ensure the preservation of, access to, and reuse of research outputs. SHARE will develop solutions that capitalize on the compelling interest shared by researchers, libraries, universities, funding agencies, and other key stakeholders to maximize research impact, today and in the future. SHARE aims to make the inventory of research assets more discoverable and more accessible, and to enable the research community to build upon these assets in creative and productive ways. ARL, AAU, and APLU strongly believe that ensuring broad and continuing access to research is central to the mission of higher education. Research publications, research data, other research outputs, along with their associated metadata, should be publicly accessible and available for reuse, text mining, data mining, and machine reading. This accelerates further research and discovery.

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• SciCrunch
• 12 years ago - by Anonymous

An experimental course and blog offered by the Harvard-Smithsonian Center for Astrophysics John G. Wolbach Library and the Harvard Library to train librarians to respond to the growing data needs of their communities. Data science techniques are becoming increasingly important to all fields of scholarship. In the hands-on course, librarians learn the latest tools for extracting, wrangling, storing, analyzing, and visualizing data. By experiencing the research data lifecycle themselves, librarians develop the data savvy skills that can help transform the services they offer. Material will be made available via the DST4L website as it progresses.

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• SciCrunch
• 12 years ago - by Anonymous