We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Web-based tool that screens for experiment-specific reference genes. Tool applying GPU-accelerated computing for determination of internal references in microRNA transcription studies.
Provides methodology to evaluate activity and efficacy of new cancer therapeutics in solid tumors, using validated and consistent criteria to assess changes in tumor burden. RECIST Working Group comprises representatives of the European Organization for Research and Treatment of Cancer (EORTC), National Cancer Institute (NCI) of the United States and Canadian Cancer Trials Group (CCTG), as well as several pharmaceutical companies. Its mission is to ensures that RECIST undergoes continued testing, validation and updating.
Uppsala Monitoring Centre, located in Uppsala, Sweden, is the field name for the World Health Organization Collaborating Centre for International Drug Monitoring. UMC works by collecting, assessing and communicating information from member countries' national pharmacovigilance centres in regard to benefits, harm, effectiveness and risks of drugs since 1978.
International reference guide for medicinal products maintained by the Uppsala Monitoring Centre. With its unique drug code hierarchy and extensive coverage, it provides consistent drug dictionary with exact terminology when coding concomitant medications. Dictionary is used to identify drug names and evaluate medicinal product information, including active ingredients and products’ anatomical and therapeutic classifications, from nearly 150 countries. Data covers both conventional medicines and herbal remedies. Data is continuously updated, with new releases twice a year, on 1 March and 1 September.
ECOG Performance Scale describes patient’s level of functioning in terms of their ability to care for themself, daily activity, and physical ability (walking, working, etc.). Standard criteria for measuring how the disease impacts patient’s daily living abilities. Used to assess the functional status of patient.
Open-source DataFrame library for data manipulation known for being one of the fastest data processing solutions on single machine. Features well-structured, typed API that is both expressive and easy to use. DataFrame interface on top of OLAP Query Engine implemented in Rust using Apache Arrow Columnar Format as the memory model.
Software tool for phasing and assembly of bacterial strains from long-read sequencing data (either Oxford Nanopore or PacBio). Given reference (or collapsed de novo assembly) and set of aligned reads as input, tool produces multi-allelic phasing, individual strain haplotypes and strain-specific variant calls. Used for phasing and assembly of strain haplotypes from long-read metagenome sequencing.
Core offers comprehensive instrumentation and technical support for all aspects of in vitro and in vivo pre-clinical non-human anatomical and molecular imaging. Studies may be conducted on samples prepared to exhibit characteristic features for a particular imaging modality. Within the intact environment, physiological and pathophysiological activity may be observed through imaging or numerous biological pathways and interactions involved in injury and disease progression, such as traumatic brain injury, cardiac disease, tumorigenesis, and therapeutic interventions.
Software MATLAB toolbox for interacting with the Allen Brain Observatory.
S220 Focused-ultrasonicator is based on Covaris Adaptive Focused Acoustics technology. Instrument designed for tissue homogenization, cell lysis, DNA or chromatin shearing, and other sample preparation steps. The system is comprised of the Treatment System which delivers the acoustic energy to the sample, the Safety System which protects users from inadvertently contacting the high intensity acoustic energy, and the Computer and Application Software which provides users an interface to control the device.
Core team of computational scientists and software engineers provide serivces to bring high-performance computing to research projects under the Institute of Computational and Data Sciences at the Pennsylvania State University.
Visualization Hub provides immersive technologies, knowledge, and skills to the Penn State community with the goal to create leadership in immersive experiences by advancing the underlying science and integrating it into the academic spectrum through research, education, and outreach. Provides research and development support for immersive technology projects. Projects can range from developing virtual reality (VR), augmented reality (AR), mixed reality (MR) applications or experiences, access to VR/AR/MR hardware, digital twins, creating 3D models, etc.
Provides advanced cyberinfrastructure resources including large scale compute and data storage. to the Penn State University research community under the operation of the Institute of Computational and Data Sciences
Transmission electron microscope designed for general-purpose, high-resolution imaging of both biological and non-biological samples, offering capabilities like bright-field, dark-field, and diffraction modes, typically utilizing LaB6 electron gun and operating within voltage range of 20-120kV; it's particularly well-suited for analyzing the ultrastructure of delicate specimens with high contrast due to its "BioTwin" features, allowing for low-dose imaging of beam-sensitive samples like cryo-preserved biological materials.
Core provides data science analysis support, training and promotion of data science education for undergraduate and high school students in the state of Oklahoma. Services include 1) Global analysis of gene expression data using custom spotted microarrays and commercial Affymetrix and Combimatrix arrays to examine gene expression patterns in mice, adenovirus-infected cells, and a variety of bacterial systems. 2) Genome annotation and comparative genomics analysis, including studies on several bacterial and viral pathogens important for human and agricultural disease. Informatics support for genome sequencing projects, annotation support, and post-sequence studies. Bioinformatics educational include analysis of laboratory data for DNA barcoding, instructional materials for protein structure analyses and phylogenetic analyses, and microbial and viral genome sequence annotation and analysis, career counseling to undergraduate students, both individually and in large groups, supervision of undergraduate summer interns and high school interns to enhance interest in pursuing bioinformatics as a career path, providing instructional materials for high school teachers interested in incorporating bioinformatics into their lesson plans.
College of Medicine Flow Cytometry and Cell Sorting Facility (formerly SMACC) at Texas A&M Health provides cell analysis and cell sorting services and is managed by Department of Microbial Pathogenesis and Immunology.
Mouse monoclonal anti-TPO antibody labeled with acridinium ester. Mouse monoclonal anti-TPO antibody covalently coupled to paramagnetic particles.
Core provides service, equipment, protocols, and training to help investigators differentiate healthy skin from skin with abnormal immune responses at the cellular and molecular level, to enable biomarker identification as well as to increasing our knowledge of skin immune responses.
Core offers assistance in experimental design, sample preparation, library prep, sequencing, data analysis and bioinformatics. Provides experience working with non-human primate genomes and other non-standard genomes in addition to the more commonly studied human and mouse genomes. Provides expertise in the use of transcriptomics and genomics to study immune responses and repertoires.Houses Illumina NovaSeq 6000 and Illumina MiSeq.
Core provides services and R&D in cell engineering and gene expression modifications by using retro- and lentivirus, adenovirus, adeno-associated virus, shRNA/MIR and CRISPR-Cas9 genome editing methods.