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Database of the most recent sequence updates and annotations for the T. brucei genome. New annotations are constantly being added to keep up with published manuscripts and feedback from the Trypanosomatid research community. You may search by Protein Length, Molecular Mass, Gene Type, Date, Location, Protein Targeting, Transmembrane Helices, Product, GO, EC, Pfam ID, Curation and Comments, and Dbxrefs. BLAST and other tools are available. T. brucei possesses a two-unit genome, a nuclear genome and a mitochondrial (kinetoplast) genome with a total estimated size of 35Mb/haploid genome. The nuclear genome is split into three classes of chromosomes according to their size on pulsed-field gel electrophoresis, 11 pairs of megabase chromosomes (0.9-5.7 Mb), intermediate (300-900 kb) and minichromosomes (50-100 kb). The T. brucei genome contains a ~0.5Mb segmental duplication affecting chromosomes 4 and 8, which is responsible for some 75 gene duplicates unique to this species. A comparative chromosome map of the duplicons can be accessed here (PubmedID 18036214). Protozoan parasites within the species Trypanosoma brucei are the etiological agent of human sleeping sickness and Nagana in animals. Infections are limited to patches of sub-Saharan Africa where insects vectors of the Glossina genus are endemic. The most recent estimates indicate between 50,000 - 70,000 human cases currently exist, with 17 000 new cases each year (WHO Factsheet, 2006). In collaboration with GeneDB, the EuPathDB genomic sequence data and annotations are regularly deposited on TriTrypDB where they can be integrated with other datasets and queried using customized queries.

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• SciCrunch
• 16 years ago - by Anonymous

Collect, bank, and distribute human tissue and fluid specimens by uniting tissue-based research resources within the OSU Department of Pathology and promoting collaborative research within the OSU Medical Center and related national human research projects. The HTRN is comprised of the Pathology Core Facility (PCF), Tissue Archive Service (TAS), Tissue Procurement Service (TPS), AIDS and Cancer Specimen Resource (ACSR), the Cancer and Leukemia Group B Pathology Coordinating Office (CALGB - PCO), and an Adenoma Polyp Tissue Bank (APTB).

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• 16 years ago - by Anonymous

In collaboration with several research groups at Jackson Laboratory, we mapped the tissue-specific functional relationship networks in the laboratory mouse by simulating the natural tissue specificity realized by differential protein expression between tissues. MouseMAP is an interface that allows browsing networks of different tissues and the comparison between them. The current version of MouseMAP includes one global network as an extension of mouseNET (http://mousenet.princeton.edu) and 107 tissue-specific networks organized into 15 different major body systems. The interface has the following features (their usage are detailed in Help and FAQ page): 1. Single graph query with one or multiple genes of interests. 2. Expansion/shrinking of query results through edge or node cutoffs. 3. Comparison of local networks between different tissues. 4. Dynamic generation of figure legend to facilitate manuscript writing.

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• SciCrunch
• 15 years ago - by Anonymous

This website offers educational materials and information on services of the UAB Traumatic Brain Injury Model System (UAB-TBIMS) along with links to national organizations, government agencies, and educational resources related to traumatic brain injury. The UAB-TBIMS is one of 16 national TBI Model Systems Centers working to maintain and improve a cost-effective, comprehensive service delivery system for people who incur a traumatic brain injury. A Model System must demonstrate outstanding care to individuals with traumatic brain injury, from the emergency medical services, to acute care in the hospital, to rehabilitation. The UAB TBIMS * conducts research, * distributes their research findings to both clinical and consumer audiences * collaborates with other clinical research programs and * participates in the Model Systems Database. This Center, operates within the UAB Department of Physical Medicine and Rehabilitation, which is located at Spain Rehabilitation Center in the UAB Hospital complex. Here it establishes and maintains links with emergency medical service agencies throughout the state, with state vocational rehabilitation and long-term follow-up programs.

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• SciCrunch
• 15 years ago - by Anonymous

Ontology of phenotypic qualities, intended for use in a number of applications, primarily defining composite phenotypes and phenotype annotation. The new PATO differs from the old in that the system of attributes and values has been abandoned in favor of a single hierarchy of qualities. PATO is designed to be used in conjunction with ontologies of quality-bearing entities. An example of such an entity is an insect eye (taken from the fly_anatomy ontology), which could be the bearer of the quality ''red'' (PATO:0000322). This combination is the red eye phenotype. We say that the phenotype term is ''post-coordinated'', as it is formed by coordinating two terms together. This is in contrast to ontologies of pre-coordinated phenotypes, such as the Mammalian Phenotype (MP) ontology. PATO is independent of any exchange format or database schema. One way of expressing phenotype annotation using PATO is pheno-syntax, or pheno-xml. They will also post recommendations for representing phenotypes using OWL. All representations share the same basic formal underpinnings, a combination of quality-bearing entity and a quality (the EQ model).

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• SciCrunch
• 16 years ago - by Anonymous

The molecular lab at Weld Hill is well equipped for modern molecular studies, from RNA expression studies to phylogenetic analyses.

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• SciCrunch
• 13 years ago - by Anonymous

At the Website of the Causal Cognition Group (CCG) of the University of M��laga, you may read information about our group, its members, our research, main activities, and more. Our main interests are cognitive psychology and learning, and more recently cognitive neuroscience, physiological correlates of learning and cognitive control. This site is in constant evolution... though there are things that hardly change: Cognitio rei per causas.

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• SciCrunch
• 15 years ago - by Anonymous

BrainPod is the podcast from the journal Neuropsychopharmacology. Join us as we delve into the latest basic and clinical research that advance our understanding of the brain and behavior, featuring highlighted content from a top journal in fields of neuroscience, psychiatry, and pharmacology.

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• SciCrunch
• 16 years ago - by Anonymous

One of the largest financiers of research in Sweden that promotes scientific research, teaching and/or education beneficial to the Kingdom of Sweden. 20-30 percent of the Foundation''s grants relate to high-value research equipment for use within the technical, natural sciences and biomedical fields, and about 50 percent relate to major research projects and substantial scientific networks. Universities, academies and similar research and educational institutions are eligible for grants within the following fields: * Expensive scientific equipment * Fellowship programs initiated by the Foundation * Selected research projects of significant potential * Larger educational research projects Applications may be submitted by individual scientists, or research groups affiliated to a Swedish university or equivalent institution. An application may also be submitted by the management of a university, university college, scientific academy, or national research associations. Applications from private individuals without connection to a scientific institution are not considered.

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• SciCrunch
• 16 years ago - by Anonymous

Software pipeline to detect structural variants (SVs) by integrating calls from several existing SV callers, which are then validated and the breakpoints refined using local de novo assembly. The output is in BED format allowing for easy downstream analysis or viewing in a genome browser. It is modular and extensible allowing new callers to be incorporated as they become available.

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• SciCrunch
• 13 years ago - by Anonymous

Biomet and Interpore Cross are on the cutting edge of technology in the orthopedic biomaterials market. Our focus is developing and providing truly innovative products, which meet the rapidly expanding needs of orthopedic surgeons both today and in the future. Our Pro Osteon resorbable bone graft material is derived from an abundant non-decorative coral. Pro Osteon is available in a selection of fully resorbable sterile granules and blocks, in a variety of shapes and sizes. Our InterGro DBM products combine the osteoinductivity of DBM with a natural, non-soluble carrier that won''t wash away, delivering a unique bone graft that offers superior handling and performance characteristics. This highly-moldable composite graft can be easily formed to fit any shape fracture or defect.

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• SciCrunch
• 16 years ago - by Anonymous

The Barth Syndrome Registry and Repository (BRR) at the University of Florida and Children''s Hospital Boston was created to provide additional information about this rare disorder. By collecting information directly from families and abstracting medical information from patient records, we hope to build a large anonymized database that is useful for answering scientific research questions and that is a source of medical information. Additionally, we are collecting blood samples for DNA isolation and storage and for the development of special cell lines. These tools will allow researchers to better understand the cellular and genetic nature of this disease and how these abnormalities may impact the clinical variability of Barth syndrome patients. Currently available data from the Barth Syndrome Registry and Repository includes self-reported data. This includes basic demographics, age at diagnosis of Barth Syndrome, reason for diagnosis, family history; symptoms, presence or absence of a history of cardiomyopathy, history regarding hospitalizations, cardiac transplant or listing for transplant, presence or absence of a history of neutropenia; history of infections, medical therapy and basic developmental history. We are in the process of abstracting medical data to build a more complete medical database and may be able to provide additional data with a specific request. Currently the DNA bank has data from 65 patients, genomic DNA from 50 patients, lymphoblast lines from 41 patients, fibroblast lines from 3 patients, and myocardium/autopsy from 3 patients. However, this is increasing as new patients enroll in the Registry. Please contact us with questions and specific requests about data or specimens.

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• SciCrunch
• 16 years ago - by Anonymous

http://dctd.cancer.gov/FundingPartnerships/PAsRFAs.htm

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• 18 years ago - submitted by Timothy Tsui

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• 18 years ago - submitted by Stephen Larson

Webserver for taxonomic classification of metagenomic reads.

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• SciCrunch
• 13 years ago - by Anonymous

Database of genes regulated by pain derived from published manuscripts describing results of pain-relevant knockout studies. The database has two levels of exploration: across-gene and within-gene. The across-gene level, the PainGenesdbSelector, is encountered first. All genes in the database can be accessed and sorted by their gene name, protein name, common names and acronyms, or genomic position (by navigating a graphic representation of the mouse genome). The gene and protein names can be selected from an alphabetical list, or by typing a text string into a search box.

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• SciCrunch
• 16 years ago - by Anonymous

GENEticS is arap video about genetics. So let''s talk about genes, and I don''t mean trousers, go the lyrics to this catchy rap video created for The GAMY (Genetics and Merthyr Youth) Project. It is one of the many videos, games, and digital media used by researchers at the University of Glamorgan in the United Kingdom use to engage local teenagers in a conversation about genetics. Video produced by Jon Chase (aka Oort Kuiper).

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• SciCrunch
• 16 years ago - by Anonymous

UniProt Archive (UniParc) is part of UniProt project. It is a non-redundant archive of protein sequences extracted from public databases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, PIR-PSD, EMBL, EMBL WGS, Ensembl, IPI, PDB, PIR-PSD, RefSeq, FlyBase, WormBase, H-Invitational Database, TROME database, European Patent Office proteins, United States Patent and Trademark Office proteins (USPTO) and Japan Patent Office proteins. UniParc contains only protein sequences. All other information about the protein must be retrieved from the source databases using the database cross-references. Each unique sequence is stored only once with a stable identifier. The format of the identifier is UPI followed by ten hexadecimal numbers, e.g. UPI000000000A. UniParc proteins are linked to their source databases by database cross-references. Each cross-reference links one protein in UniParc to an accession number in a source database. The database cross-reference is active as long as the sequence identified by the source accession number remains unchanged. When the sequence is modified or removed in the source database, the cross-reference from UniParc becomes inactive. Active cross-reference can be used to directly access the source databases but inactive cross-references can only be used to access sequences archives, such as the Sequence Version Archive. UniParc is available for text- and sequence-based searches. Sequences, which are no longer part of any source database, are excluded from sequence-based searches, but they are available for text-based SRS searches. Performing a similarity search against UniParc is equivalent to performing the same search against all databases cross-referenced in UniParc, as UniParc contains all proteins from its source databases. Sequence similarity searches can be done using FASTA, BLAST or Mpsrch.

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• SciCrunch
• 16 years ago - by Anonymous

Founded in 1995, the Southeastern Brain Tumor Foundation (SBTF), a 501c3 not-for-profit charitable foundation, is devoted to improve the quality of life for brain tumor patients and their families. By offering information, education and support services, we aspire to instill hope, knowledge and comfort to all involved. The Southeastern Brain Tumor Foundation also raises funds for research and medical personnel so that a cure can be found. For over a decade, the SBTF has become a well-known fundraising entity supporting critical, cutting edge brain tumor research at major medical centers in the Southeast. Our annual Race for Research held in Atlanta, Georgia each summer, is our main fundraising event popular throughout Atlanta and the surrounding metropolitan area and has funded over $1.2 million dollars in research grants to leading researchers at major medical centers throughout the Southeast over the past decade. We are proud of our dedicated, all volunteer Board of Directors who meet monthly. Our Board is a diverse group comprised of individuals who''ve been touched by brain tumors in many different ways. Ranging from patients and family members to healthcare professionals; we are all committed to promoting the awareness of brain tumors in the community, communicating with patients and families and raising critical funds for research grants furthering advancements in the treatment of brain tumors. Our monthly support group, lead by a nurse practitioner, welcomes patients and their families to sit side by side with each other, share their experiences, communicate and receive support. As a neurosurgeon-scientist focused on the treatment of patients with brain tumors, I am committed to advancing the mission of SBTF forward in the fight against brain tumors. Our ability to serve the brain tumor community is dependent on each of you. Whether you support us with a financial donation in our fundraising efforts or with your time as a volunteer, each of you are a vital and integral part of our success and we thank you.

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• SciCrunch
• 15 years ago - by Anonymous

The Loma Linda University Cancer Center Biospecimen Laboratory provides specimens for researchers as they search for the causes of cancer, and look for new means of prevention and treatment. The specimens include tissues, blood products (blood cell, plasma and serum) and bone marrow cells. Researchers interested in gaining access to the Biospecimen Laboratory''s samples should email Dr. Saied Mirshahidi, requesting access. The number and types of samples we have available for research can be viewed, http://www.llu.edu/catissuesummary/. Use the Biospecimen Laboratory Tissue Request Form to request specimens for research studies.

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• SciCrunch
• 16 years ago - by Anonymous