Curator Dashboard

Core provides electron microscopy services including Sample preparation from tissues, cell culture, cell suspension; Sample preparation for materials science; Preparation of semi-thin sections; Preparation of ultrathin sections for classical TEM , REM and serial reconstruction;Contrast methods for TEM samples, SEM samples, negative contrast, coating methods for SEM; Classical TEM and REM; Immunogold technique;Tokuyasu freeze-cutting technique; Cryo-substitution; Cryo-electron microscopy; Electron tomography; 3D array tomography; SBF-SEM; Image documentation and digital processing; Technical-preparative adjustments; Provision of infrastructure (sample preparation, electron microscopes, individual user training); Creating image documentation and evaluations; Image processing techniques and quantitative evaluation techniques (Image J, Fiji/TrakEM2, IMOD/3Dmod, Amira 5, ZEN Connect, etc.); Publication consulting.

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• 1 month ago - submitted by Sara Timm

Web tool for prediction of changes in protein-protein binding affinity on mutations. Predictor of changes in binding free energy induced by point mutations. It relies on a set of statistical potentials derived from known protein structures, and combines the effect of the mutation on the strength of the interactions at the interface, and on the overall stability of the complex.

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• 1 month ago - by Anonymous

Electronic Lab Notebook digital platform designed to help researchers organize, store, and share experimental notes, protocols, and data. Acting as a modern replacement for traditional paper lab notebooks, it operates as an institution-wide research data management (RDM) system.

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• dkNET
• 1 month ago - submitted by Rob Day

stringent 21CFR11 complaint ELN document / file / data manager for centralizing all your lab's knowledge assets in one place. Can be hosted on-premise, on the cloud and even in a totally sealed network with no internet connection for maximum security. Extremely flexible, works like a cross-platform, secure, collaborative GLP operating system and file server. Supports storage and viewing and versioned editing of any file type in any format.

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• dkNET
• 1 month ago - submitted by Rob Day

Spacial neuron gene expression atlas. Interactive, server-free web application and spatial transcriptomics database designed to help researchers map and analyze gene expression within the brain. Mouse whole brain spatial transcriptomic atlas.

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• 1 month ago - submitted by Lindsay Meyerdirk

Facilitates multi‐disciplinary collaboration among imaging scientists and clinicians at academic institutions within the Milwaukee region. Manages MCW research imaging facilities and provides access to MCW faculty imaging specialists. Services include performing mixed research and advanced clinical outpatient imaging to support clinical evaluation trials and basic science/technology research.

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• 1 month ago - by Anonymous

Core is part of the University of Pittsburgh Center for Biologic Imaging. Provides expertise in the design and implementation of experiments that use microscopy techniques and image analysis, including interpretation of morphological data. Services include to prepare, store and optimally analyze tissues and cells via morphological and mRNA and protein localization techniques; provide fixed cell and tissue imaging to Hillman investigators; provide live cell, live tissue, and live animal imaging to Hillman project leaders; perform detailed electron microscopy analysis of tissue structure; provide training related to use of and access to all instrumentation; Assist with experimental design and refinement, and evaluate experimental results including developing and implementing appropriate software algorithms to provide quantitative measurements.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Software R package provides access to the iLINCS (Integrative LINCS) database for drug repurposing and functional genomics research. Enables systematic analysis of gene expression signatures against comprehensive databases of Gene Knockdown signatures, Gene Overexpression signatures, Chemical Perturbagen signatures.

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• 1 month ago - submitted by Ali Sajid Imami

Zeiss Crossbeam 550 (sometimes referred to as the XB 550) is dual-beam system that combines the Gemini 2 SEM with the Ion-sculptor FIB (Focused Ion Beam) for advanced materials analysis and sample preparation. XB 550 combined with the Leica EM VCT 500 is a highly specialized system designed for advanced cryogenic workflows in materials and life sciences. It enables researchers to investigate and prepare samples at ultra-low temperatures without exposing them to air or contamination.

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• 1 month ago - submitted by Danielle Jorgens

Software highly performant messaging and multiprocessing data framework designed for building modular, high-performance signal processing pipelines. It is built in Python with no dependencies, making it easy to install and use.

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• 1 month ago - submitted by Brock Wester

Core Facility is located in the Natural Science and Engineering Research Laboratory. Provides support for basic and translational research in biological and interdisciplinary sciences through its instruments. Core has advanced imaging systems including confocal microscopes, high-throughput slide scanner, multiphoton intravital microscope, electron microscopes, and various other optical instruments. Houses workstations equipped with advanced image analysis software such as Imaris and cellSens Dimension. Provides support for processing and embedding of tissue samples, sectioning and slide preparation, and cell culture.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Web professional CV/resume writing service that helps job seekers tailor their applications for specific industries like tech, executive, or engineering. Auto-generates clean, customizable academic CVs from open research data (OpenAlex, ORCID, Crossref, DataCite, Open Editors Plus) free for individuals, open-source, FAIR by design.

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• 1 month ago - by Anonymous

Gene Pulser Xcell modular electroporation system includes main unit, two accessory modules, and the ShockPod cuvette chamber. Used in biological research to introduce foreign macromolecules (like DNA, RNA, or siRNA) into cells.

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• 1 month ago - submitted by Meric Birben

Specialized surgical tool designed to insert neural probes and implants into the brain with high precision and minimal tissue damage. Used in pre-clinical neuroscience research to improve the longevity and signal quality of chronic neural implants (such as microwire arrays or silicon probes).

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• RRID
• 1 month ago - by Anonymous

Software Python pipeline for constructing interoperable scientific knowledge graphs from unstructured literature. It extracts structured information from scientific papers using LinkML schemas and large language models, with integrated knowledge graph retrieval-augmented generation (RAG) to reduce hallucination. Designed for interdisciplinary scientific domains.

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• SciCrunch
• 1 month ago - by Anonymous

Molecular Education, Technology and Research Innovation Center (METRIC) is an NC State University-wide Shared Core Research Facility administered by the Office of Research and Innovation. We provide internal and external researchers with access to instrumentation and technical expertise across three primary analytical platforms: Mass Spectrometry: Supports qualitative and quantitative analyses, including high-resolution accurate mass (HRAM) measurements, proteomics, metabolomics, and small molecule analysis. Magnetic Resonance (NMR & EPR): Provides structural and dynamic characterization of molecules in solution. Capabilities include multi-nuclear solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy for studying paramagnetic species, transition metal complexes, and free radicals. X-Ray Diffraction: Offers atomic-level structural determination. The facility is equipped for single-crystal X-ray diffraction of both small molecules (including absolute configuration determination) and macromolecules/proteins.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Litesizer DLS delivers particle sizing data with automatic angle selection to prevent errors, while MAPS technology yields the highest-possible peak resolution. Continuous transmittance monitoring detects sedimentation and agglomeration during measurement, enhancing measurement reliability.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Autosorb instruments are high-vacuum physisorption and chemisorption analyzers designed for advanced measurement of BET surface area, active area, and pore size distribution. Designed for measurements of specific surface area and pore size distributions from 0.35 to 500 nm.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Laser diffraction instrument for particle size determination in liquid and dry dispersion. Sample size range: 100 nm to 1 mm. One solid state lasers, 830 nm.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

XRDynamic 500 offers XRD data quality with optimal solutions for powder XRD, non-ambient XRD, PDF analysis, SAXS, and more with fully automated optics and alignment routines.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth