Curator Dashboard

A short-read assembler based on a de Bruijn graph, capable of assembling a human genome on a desktop computer in a day.

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• SciCrunch
• 13 years ago - by Anonymous

The Nervous System In Action by Michael D. Mann, Ph.D. is a textbook on nervous system physiology. Available here is the web accessible version of of this textbook. An Adobe Acrobat (PDF) version is also supplied for better printing. You will need Acrobat Reader to see and print it. The textbook consists of the following: Preface (1) Neurophysiology, An Overview (2) Human Behavior (3) 1. Diffusion and Transport (4) 2. Control Systems and Homeostasis (5) 3a. Properties of Excitable Membranes: The Membrane Potential (6) 3b. Properties of Excitable Membranes: The Spike (7) 4a. Receptor Properties: Receptor Potentials and Coding (8) 4b. Sensory Receptors II (9) 5. Somesthesia--Peripheral Mechanisms (0) 6. Somesthesia--Central Mechanisms (a) 7. Vision (b) 8. Audition (c) 9. The Vestibular System (d) 10.Gustatory and Olfactory Senses (e) 11. Muscle Receptors (f) 12. Peripheral Nerves (g) 13. Synapses (h) 14. Muscle Contraction (i) 15. Reflexes (j) 16. Initiation and Control of Movement (k) 17. Activities Involving the Cerebral Hemispheres (l) 18. The Clinical Implications of Neurophysiological Concepts (m) 19. Learning and Memory Appendix: Common abbreviations (n) Glossary (o) Index (p)

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• SciCrunch
• 15 years ago - by Anonymous

Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance (SCCA) have merged to form Fred Hutchinson Cancer Center, unified adult cancer research and care center. Independent, nonprofit organization is clinically integrated part of UW Medicine and is UW Medicine’s cancer program.

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• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented September 2, 2016. A clinical database and PTB were created in 1990 and 2000, respectively, to collect clinical information and biospecimens from patients with suspected or confirmed pancreatic cancer, other pancreatic diseases, and tumors of the duodenum, ampulla of Vater, and distal bile duct. Standard procedures for biospecimen collection and data entry were developed. The use of human tissue for research is an invaluable tool to understand the basic mechanisms of tumor biology, which will hopefully lead to the development of new therapeutic approaches to pancreatic cancer treatment. The cornerstone of any large translational research program is the development of an accurate and comprehensive tumor bank. All tumors removed in the operating room are sampled for careful pathologic study and the remainder of the tumor is promptly stored in our Pancreas Tissue Bank (PTB) to be used for research. Other samples, including blood, pancreatic juice and biopsy material, can also be utilized to identify early markers for pancreatic cancer. The molecular profile of tumors in the PTB can be linked to information in our clinical database to provide insight on the relationship between molecular events and clinical outcome. Patients may contribute to the tissue banking effort by choosing to participate in select research protocols. Protecting patient privacy is of great importance and thus, to maintain the confidentiality of health information, the PTB complies with all federal and institutional regulations governing research with human participants.

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• SciCrunch
• 16 years ago - by Anonymous

Stem cell and bone marrow register in the United Kingdom, managing and recruiting donors internationally for patients who require stem cell transplants. A database of tissue-typing results of all prospective donors is maintained. A national cord blood program consisting of both a cord blood bank and a research institute provides donated umbilical cord blood for use in clinical transplants and research. Research is conducted in immunogenetics, immunotherapy, bioinformatics (curating the World Health Organisation HLA Nomenclature database, ensuring that all new tissue types are consistently documented), and immune reconstitution.

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• SciCrunch
• 16 years ago - by Anonymous

The AIDS Specimen Bank (ASB) provides repository services to cohort studies such as the Women''s Interagency HIV Study (WIHS), Primary HIV Infection Study, Staying Well Study, clinical trials performed at UCSF, and others. The majority of ASB clients are HIV investigators, but the bank also processes and stores specimens collected from some non-HIV studies. The ASB is also the Specimen Bank Core for the UCSF/GIVI Center for AIDS Research. The mission of the AIDS Specimen Bank is to provide the following: * Processing and handling of specimens * Short-term or long-term storage (includes ultra-low temperatures and liquid nitrogen) * Data management * Well-characterized specimens to qualified investigators for translational research * Consultation to investigators inquiring about specimen collection and storage * International resource for HIV research * Networking tool within the research community All body fluids����??sera, plasma, saliva, vaginal lavage, etc.����??are stored as 1-milliliter aliquots in ultra-low freezers (-70��������C). PBMCs are processed and stored in liquid nitrogen. All equipment involved with the processing of specimens (centrifuges and Coulter counter) is calibrated by trained technicians. The ASB is a participant in the Adult AIDS Clinical Trials Group PBMC Cryopreservation and Viability Panel, in which sets of processed and frozen PBMCs are sent to the Immunology Quality Assessment Program (IQA) testing lab for viability and cell counts. Our laboratory has participated in the IQA program for three years, and all samples have proven to be acceptable to their standards. The ASB is compliant with Good Laboratory Practices guidelines.

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• SciCrunch
• 16 years ago - by Anonymous

A software pipeline for analyzing deep sequencing maps of chromatin structure.

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• SciCrunch
• 13 years ago - by Anonymous

Association of physicians, scientists, academics, research institutes and self-help groups that provides and nurtures interdisciplinary cooperation between research and primary, secondary and tertiary health care. Many internationally renowned heart failure researchers and working groups live and work in Germany. Nevertheless, there is insufficient cooperation of the respective working groups and research projects in this area. In order to remain internationally competitive in the heart failure research community, excellent implementation of large scale clinical and genetic trials is indispensable. Further, deficits in the effective presentation and transfer of research findings into clinical practice need to be addressed. An adequate translation of guidelines into practical, tangible instructions can facilitate clinical practice both in primary and tertiary care fundamentally. The need for action to address the research-practice-gap is obvious.

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• SciCrunch
• 15 years ago - by Anonymous

WikiDoc is the Original Medical Wiki / Encyclopedia. 71,700 Textbook Chapters and News Articles in English are available and anyone may edit this medical news service and textbook of medicine. Major sections include WikiDoc News: Today in Medicine, Co-Author The World''s Largest Textbook of Medicine, Community, and Care. WikiDoc is available in other languages including Espa��ol, Fran��ais, Polski, , Rom��n, , and T��rk��e.

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• SciCrunch
• 16 years ago - by Anonymous

Database of dermatology cases and browsable by diagnosis, category or body site with 12,176 images, 583 contributors and dermatology links. You may retrieve images using any diagnosis, disease category, body site, pigmentation, image contributor, patient age, image name, and/or key words. You are welcome submit images or to download images for lectures and other teaching purposes - or with permission for other uses. Additionally, you may search DermAtlas from your website. Add YOUR Link On the DermAtlas'''' Add a Link Page you can associate your link with as many diagnoses as you like. Case submission If you have a high quality image that you would like to submit to DermAtlas, submit the requested information, and upload the image. The data and image will automatically be sent to the editors for review. You will be notified within one week of submission of images. In order for an image to be considered for inclusion into this collection, consent must be obtained from the patient or his/her legal guardian. Contributors are solely responsible for obtaining consent.

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• SciCrunch
• 16 years ago - by Anonymous

United Network for Organ Sharing (UNOS) is the private, non-profit organization that manages the nation''s organ transplant system under contract with the federal government. UNOS is involved in many aspects of the organ transplant and donation process: * Managing the national transplant waiting list, matching donors to recipients 24 hours a day, 365 days a year. * Maintaining the database that contains all organ transplant data for every transplant event that occurs in the U.S. * Bring together members to develop policies that make the best use of the limited supply of organs and give all patients a fair chance at receiving the organ they need, regardless of age, sex, ethnicity, religion, lifestyle or financial/social status. * Monitoring every organ match to ensure organ allocation policies are followed. * Provides assistance to patients, family members and friends. * Educates transplant professionals about their important role in the donation and transplant processes. * Educating the public about the importance of organ donation. UNOS was first awarded the national Organ Procurement and Transplantation Network (OPTN) contract in 1986 by the U.S. Department of Health and Human Services. UNOS continues as the only organization ever to operate the OPTN. As part of the OPTN contract, UNOS has: * established an organ sharing system that maximizes the efficient use of deceased organs through equitable and timely allocation * established a system to collect, store, analyze and publish data pertaining to the patient waiting list, organ matching, and transplants * informed, consulted and guided persons and organizations concerned with human organ transplantation in order to increase the number of organs available for transplantation

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• SciCrunch
• 16 years ago - by Anonymous

Public university ranked established in 1972. Courses taught entirely in English, related to the world of business, engineering, culture, art and Spanish society.

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• SciCrunch
• 17 years ago - submitted by Eddy Kim

Fox Chase Cancer Center is the region''s only hospital devoted entirely to cancer treatment, research and prevention. Our 100-bed hospital, located in Philadelphia, is consistently ranked by U.S. News and World Report among the top cancer centers in the nation. Our nationally and internationally recognized staff provides consultations and treatment recommendations for all types of adult cancer. Fox Chase Cancer Center is an independent, nonprofit institution formed in 1974 by the union of American Oncologic Hospital (one the the nation''s first cancer hospitals, established in 1904) and the Institute for Cancer Research (founded in 1927). Fox Chase was also among the first institutions to be designated a National Cancer Institute Comprehensive Cancer Center in 1974. In September 2000, the Hospital of Fox Chase Cancer Center became the nation''s first comprehensive cancer center and Pennsylvania''s first hospital to receive Magnet status for nursing excellence from the American Nurses Credentialing Center, which renewed this honor in 2004 and again in 2009, making it the first hospital in Pennsylvania to have achieved two successful Magnet renewals. The Women''s Cancer Center builds on Fox Chase''s world-renowned expertise in breast and gynecologic cancers. The Center offers women a place where they can receive coordinated, state-of-the-art care, support services, and education all under one roof.

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• SciCrunch
• 16 years ago - by Anonymous

Public research university in Lincoln, England. The University has origins that trace back to 1861, and obtained university status in 1992 and its present name and structure in 2001.

• Organization
• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Various non-redundant databases with different sequence identity cut-offs created by clustering closely similar sequences to yield a representative subset of sequences. In the UniRef90 and UniRef50 databases no pair of sequences in the representative set has >90% or >50% mutual sequence identity. The UniRef100 database presents identical sequences and sub-fragments as a single entry with protein IDs, sequences, bibliography, and links to protein databases. The two major objectives of UniRef are: (i) to facilitate sequence merging in UniProt, and (ii) to allow faster and more informative sequence similarity searches. Although the UniProt Knowledgebase is much less redundant than UniParc, it still contains a certain level of redundancy because it is not possible to use fully automatic merging without risking merging of similar sequences from different proteins. However, such automatic procedures are extremely useful in compiling the UniRef databases to obtain complete coverage of sequence space while hiding redundant sequences (but not their descriptions) from view. A high level of redundancy results in several problems, including slow database searches and long lists of similar or identical alignments that can obscure novel matches in the output. Thus, a more even sampling of sequence space is advantageous. You may access NREF via the FTP server.

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• SciCrunch
• 16 years ago - by Anonymous

St. Gallen Lung Biopsy Biobank is a tissue and blood sample collation (biobank) of all patients willing to give informed consent, who are undergoing bronchoscopy and/or surgical lung resection in their diagnostic pathway for any pulmonary disease. The special feature of the proposed biobank is the collection of endobronchial biopsies, blood, and molecularly defined cell populations from tumor tissue in a quality suitable for mRNA and other protein expression techniques, which is not possible by standard biobanks.

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• SciCrunch
• 15 years ago - by Anonymous

Peer Review Radio is a weekly radio show and podcast that portions the tastiest science and prepares it for public consumption. The end goal of this program is to provide an outlet where anyone and everyone can understand current scientific issues and generate their own informed opinions. In addition, Peer Review Radio promotes careers in research and science and serves as a training ground for future scientists to acquire invaluable communication skills. Peer Review Radio was established by a group of motivated graduate students with a desire to spread their love of science. By breaking down complicated concepts into bite-sized morcels, the ''Peers'' hope to spark the curiosity of their listeners with relevant, reliable information. Our producers determine content and coordinate the activities of the journalists. To ensure variety of content, graduate students are enlisted to act as advisers in their fields of expertise and direct literature research for necessary episode scripts. Then, we get together with professors, industrial scientists, post doctoral fellows and graduate students to talk about issues in science. Also, we supplement each episode with ''what if''-type questions, critiquing of science in film, profiles of alternative careers in science, book reviews and more! Our weekly radio show will air on CHUO 89.1 FM in Ottawa, Ontario, Canada starting this Fall 2010, and with each episode we hope to address another hot topic in science without frying your frontal cortex.

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• SciCrunch
• 16 years ago - by Anonymous

High-resolution atlas template of the human cerebellum and brainstem, based on the anatomy of 20 young healthy individuals. The atlas is spatially unbiased, i.e. the location of each structure is equal to the expected location of that structure across individuals in MNI space. At the same time, the new template preserves the anatomical detail of cerebellar structures through a nonlinear atlas-generation algorithm. By using automated nonlinear normalization methods, a more accurate intersubject-alignment than current whole-brain methods can be achieved. The toolbox allows you to: * Automatically isolate cerebellar structures from the cerebral cortex based on an anatomical image * Achieve accurate anatomical normalization of cerebellar structures * Normalize functional imaging data for fMRI group analysis * Normalize focal cerebellar lesions for lesion-symptom mapping * Use Voxel-based morphometry (VBM) to determine patterns of cerebellar degeneration or growth * Use a probabilisitc atlas in SUIT space to assign locations to different cerebellar lobuli in an unbiased and informed way * Automatically define ROIs for specific cerebellar lobuli and summarize function and anatomical data * Improve normalization of the deep cerebellar nuclei using an ROI-driven normalization. The suit-toolbox requires Matlab (Version 6.5 and higher) and SPM. The newest version only supports SPM8, although it likely runs under SPM2 or 5 as well. A standalone version for the suit-toolbox is not planned. Usage of the isolation or normalization functions, however, does not require that the analysis is conducted under SPM.

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• SciCrunch
• 15 years ago - by Anonymous

Gift of Hope Organ & Tissue Donor Network is proud to serve as the federally designated not-for-profit agency that coordinates organ and tissue donation and supports families of donors in the northern three-quarters of Illinois and northwest Indiana. Since our inception in 1986, we have coordinated donations that have saved the lives of 17,000 organ transplant recipients and helped hundreds of thousands of other patients receive needed tissue transplants. As one of 58 organ procurement organizations (OPOs) that make up the nation''s organ donation system, we work with 179 hospitals in our donation service area. In managing the recovery, care and transportation of donated organs to transplant patients, we work closely with Illinois'' nine transplant centers, which operate 32 transplant programs. We also work with other transplant centers and other OPOs through the United Network for Organ Sharing (UNOS) to provide lifesaving organs for patients awaiting them. UNOS is the federally mandated registration center for organ transplant candidates in the United States. UNOS'' computer-based system matches donated organs with patients in need, in accordance with strict federal guidelines intended to ensure equitable distribution.

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• SciCrunch
• 16 years ago - by Anonymous

LifeLink Foundation is a non-profit community service organization dedicated to the recovery of life-saving and life-enhancing organs and tissue for transplantation therapy. The Foundation works in a sensitive, diligent, and compassionate manner to facilitate the donation of desperately needed organs and tissues for waiting patients, support research efforts to enhance the available supply of organs and tissue for transplant patients, improve clinical outcomes of patients post transplantation and works closely with the United Network For Organ Sharing (UNOS) to support its goals. We are committed to inspiring the public to save lives through organ donation. To make organ transplant a reality, LifeLink Foundation focuses its attention in a number of areas: Immunology Laboratory, Public Education, Fundraising, Organ Recovery.

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• SciCrunch
• 16 years ago - by Anonymous