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This is the Sackler Colloquia YouTube channel. The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, several colloquia are scheduled, typically two days in length and international in scope. Each colloquium is organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. These colloquia are made possible by a generous gift from Jill Sackler, in memory of her husband, Arthur M. Sackler.

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• 15 years ago - by Anonymous

The Arthur M. Sackler Colloquia address scientific topics of broad and current interest that cut across the boundaries of traditional disciplines. Each year, three to four colloquia are scheduled, typically two days in length and international in scope. Each colloquium is organized by a member of the NAS, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions among one hundred or more researchers with an interest in the topic. Colloquia are held at the Arnold and Mabel Beckman Center in Irvine, California, unless noted otherwise. Papers resulting from Sackler colloquia are often published as a collection in Proceedings of the National Academy of Sciences (PNAS). Colloquium papers printed in from January 1, 1996 forward are available free online. PDFs of colloquium papers published in PNAS since 1997 are also available free online through the National Academies Press, (NAP) or reprints may be purchased through the NAP online bookstore. These colloquia are made possible by a generous gift from Jill Sackler in memory of her husband, Arthur M. Sackler.

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• 15 years ago - by Anonymous

Subscribe to the National Academy of Sciences podcasts to learn more about scientists and their work, the latest in research, and key findings of National Research Council reports. * InterViews: InterViews provides first-person accounts of the lives and work of National Academy of Sciences members. In this series of one-on-one conversations, scientists talk about what inspired them to pursue the careers they chose and describe some of the most fascinating aspects of their research. * Science Sessions: The Proceedings of the National Academy of Sciences offers brief, 5-minute, nontechnical conversations with cutting-edge researchers, including members of the National Academy of Sciences, and policymakers as they discuss topics relevant to today''s scientific community. Learn the behind-the-scenes story of work published in PNAS, plus a broad range of scientific news about discoveries that affect the world around us. * News from the National Academies: Listen to the latest news conferences and public briefings on National Research Council and Institute of Medicine reports. * Sounds of Science: This informative and entertaining series puts a spotlight on the high-impact work of the National Research Council. Focusing on a wide range of critical issues in science, engineering, and medicine, these short episodes are a quick and easy way to tune in our key findings and important recommendations. * Cultural Programs: The Cultural Programs of the National Academy of Sciences presents public exhibitions, lectures, and other programs exploring the intersections of art, science, and culture. The podcast features audio recordings of past lectures and other events. * Engineering Innovation: This weekly podcast from the National Academy of Engineering highlights exciting developments in engineering and provides technical context to stories in the news. The 40-second episodes demonstrate how engineers are making an impactin energy, health, the environment, sports, and more.

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The National Academy of Sciences (NAS) is a private, non-profit society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the public good. An Act of Congress, signed by President Abraham Lincoln in 1863 at the height of the Civil War, calls upon the NAS to provide independent advice to the government on matters related to science and technology. The National Research Council was created under the NAS charter in 1916 to extend the scope of the NAS in its advisory role. The National Academy of Engineering and the Institute of Medicine were organized under the NAS charter in 1964 and 1970, respectively. Since 1863, the nation''s leaders have turned to the National Academy of Sciences for advice on the scientific and technological issues that frequently affect policy decisions. Most of the institution''s science policy and technical work is conducted by the National Research Council (NRC), which was created expressly for this purpose and which provides a public service by working outside the framework of government to ensure independent advice on matters of science, technology, and medicine. The NRC enlists the nation''s top scientists, engineers, and other experts, who volunteer their time to study specific issues. The reports that result from their deliberations have led to some of the most significant and lasting improvements in the health, education, and welfare of all Americans. The Academy''s service to government has become so essential that Congress and the White House have issued legislation and executive orders over the years that reaffirm its unique role. NAS Award in the Neurosciences - Established by the Fidia Research Foundation Awarded in recognition of extraordinary contributions to progress in the fields of neuroscience, including neurochemistry, neurophysiology, neuropharmacology, developmental neuroscience, neuroanatomy, and behavioral and clinical neuroscience. The award is given every three years and will be awarded again in 2013

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The M. J. Murdock Charitable Trust seeks to enrich the quality of life in the Pacific Northwest by providing grants and enrichment programs to non-profit organizations that seek to strengthen the region''s educational, spiritual, and cultural base in creative and sustainable ways. In addition to a special interest in education and scientific research, the Trust partners with a wide variety of organizations that serve the arts, public affairs, health and medicine, human services, leadership development, and persons with disabilities. Eligibility for scientific research grants is limited. Select public research universities and medical institutes located within the five-state region (Pacific Northwest: Alaska, Washington, Oregon, Idaho, Montana) are typically considered for funding. The Trust prefers requests for projects in the natural sciences where the main objective is the acquisition of new knowledge. However, requests for research in engineering and medicine are also eligible. Training students in conducting research is an important consideration.

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Sting Report is a database of amino acid sequences, structures, functions, and parameters. It allows users to easily extract from the Blue Star Sting Database detailed but focused information about an individual amino acid, which belongs to a structure described in a PDB file. The extracted information is presented as a series of GIF images and a table, which are generated by Blue Star Sting modules and contain values of up to 125 sequence/structure/function descriptors/parameters. The HTML page resulting from a query on Sting Report, containing the GIF images and the table, is printable, and can also be composed and visualized at a computer platform with elementary configuration.

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• 17 years ago - by Anonymous

Java software which computes a series of quality control metrics for RNA-seq data and can compare sequencing quality across different samples or experiments to evaluate different experimental parameters. The input can be one or more BAM files, and the output consists of HTML reports and tab delimited files of metrics data.

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• 13 years ago - by Anonymous

A software tool for transcript identification and quantification with RNA-Seq. The method has a two-fold advantage: on the one hand, it translates the problem as an established one in the field of network flows, which can be solved in polynomial time, with different existing solvers; on the other hand, it is general enough to encompass many of the previous proposals under the least sum of squares model.

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• 13 years ago - by Anonymous

SPROUTS is a database of predicted protein folding related data. It was designed to gather all the results from a study concerning the comparison between tools devoted to the prediction of stability changes upon point mutations. The second aim of this database is to offer simple and user-friendly tools to better visualize and analyze the results obtained. We are now able to propose three ways of visualization and analysis: the first one consists in getting raw Delta Delta G values in a table. The second one is a 2D graph representation of a computed stability score for each residue of a given sequence and for each tool. The last one is based on a Jmol applet (Jmol) with the possibility to represent the 3D structure of a given protein with symbols representing the information stored in the database. We assume that each visualization mode offers a different look on the data stored in the database and will suit to every scientists willing to query the database whether they are more used to handle 3D protein structure or 1D/2D sequence problems. Finally, the ultimate objective is to integrate these data and their analysis with other structural bioinformatic concepts in order to improve other methods that may be related to this concept. We are currently working at adding the information extracted from our other projects related to the prediction of protein folding nucleus in order to obtain a meta server devoted to the characterization of the folding core of proteins. As of today, this database has grown up and consists in more than 100 structures which have been computed for a total of around 16500 amino acids.

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• 17 years ago - by Anonymous

An integrated database for the genomics of the Lepidoptera Spodoptera frugiperda. It provides access to expressed sequence tags (EST) from Spodoptera frugiperda. ESTs from five independent cDNA libraries, prepared from three different S. frugiperda tissues (hemocytes, midgut and fat body) and from the Sf9 cell line, are deposited in the database. These tissues were chosen because of their importance in biological processes such as immune response, development and plant/insect interaction. So far, the SPODOBASE contains 29,325 ESTs, which are cleaned and clustered into non-redundant sets (2294 clusters and 6103 singletons). The SPODOBASE is constructed in such a way that other ESTs from S. frugiperda or other species may be added. User can retrieve information using text searches, pre-formatted queries, query assistant or blast searches. Annotation is provided against NCBI, UNIPROT or Bombyx mori ESTs databases, and with GO-Slim vocabulary.

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• 17 years ago - by Anonymous

A Java library to analyze next generation sequencing data and especially perform expression profiling in organisms where no well-annotated reference genome exists.

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• 13 years ago - by Anonymous

In the belief that innovation and discovery occur in direct proportion to quality of training, the Life Sciences Research Foundation administers an international program of postdoctoral fellowships in all areas of the life sciences. Since it was established, in 1981, the Foundation has attracted support from a wide variety of sponsors. The mission of the Life Sciences Research Foundation (LSRF) is to establish partnerships between those who support research in the life sciences and academic institutions for their mutual benefit. The simple vehicle for achieving this partnership is a highly competitive postdoctoral fellowship program. Fellowship Eligibility. Three-year fellowships will be awarded on a competitive basis to graduates of medical and graduate schools in the biological sciences holding M.D., Ph.D., D.V.M. or D.D.S. degrees. Awards will be based solely on the quality of the individual applicant''s previous accomplishments, and on the merit of the proposal for postdoctoral research. Persons doing a second postdoc are eligible only if they are transferring to a different supervisor''s laboratory and embarking on a new project not connected to their previous research. All U.S. citizens are eligible to apply with no geographic restriction on the laboratory of their choice. Foreign applicants will be eligible for study in U.S. laboratories. LSRF fellows must carry out their research at nonprofit institutions. LSRF fellows may change projects, laboratories, and/or institutions during the fellowship as long as the eligibility rules listed here are not violated. A person holding a faculty appointment is not eligible to apply for an LSRF fellowship. The LSRF solicits monies from industry, foundations and individuals to support postdoctoral fellowships in the life sciences. Active solicitation of funds continues, for which we need the assistance of all concerned individuals. We recognize that discoveries and the application of innovations in biology for the public''s good will depend upon the training and support of the highest quality young scientists in the very best research environments. LSRF awards fellowships across the spectrum of the life sciences: biochemistry; cell, developmental, molecular, plant, structural, organismic population and evolutionary biology; endocrinology; immunology; microbiology; neurobiology; physiology; virology. Note: There may be no more than one LSRF fellow in any one laboratory at a time.

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• 15 years ago - by Anonymous

The Albert and Mary Lasker Foundation and its programs are dedicated to the support of biomedical research toward conquering disease, improving human health and extending life. The Foundation''s mission is to foster the prevention and treatment of disease and disabilities by honoring excellence in basic and clinical science, by educating the public, and by advocating for support of medical research. The Lasker Awards The Lasker Foundation''s Awards Program recognizes the contributions of scientists, physicians, and public servants who have made major advances in the understanding, diagnosis, treatment, cure or prevention of human disease. Other Programs Although the Lasker Foundation is not a grant-giving organization, it does support select initiatives that raise awareness of medical discoveries and their benefits to human health, and that increase support for the medical science enterprise. These initiatives have included study groups, Congressional briefings, innovative web-based programs, educational forums, and scholarly studies.

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The Kavli Foundation, based in Oxnard, California, is dedicated to advancing science for the benefit of humanity, promoting public understanding of scientific research, and supporting scientists and their work. The Foundation''s mission is implemented through an international program of research institutes, professorships, symposia and other initiatives in the fields of astrophysics, nanoscience, neuroscience and theoretical physics. The Foundation is also a founding partner of the Kavli Prizes, which recognize scientists for their seminal advances in astrophysics, nanoscience and neuroscience. To date, The Kavli Foundation has made grants to establish Kavli Institutes on the campuses of the University of California Santa Barbara, Stanford University, the California Institute of Technology, the University of Chicago, Columbia University, Yale University, Cornell University, the University of California San Diego, Delft University of Technology in the Netherlands, the Massachusetts Institute of Technology, Peking University, the Chinese Academy of Sciences, Harvard University, the University of Cambridge and the Norwegian University of Science and Technology. In addition to the Kavli Institutes, six Kavli professorships have been established: two at the University of California Santa Barbara, one at University of California Los Angeles, one at the University of California Irvine, one at Columbia University, and one at the California Institute of Technology. The Kavli Futures Symposia a series of high quality scientific symposia on topics of emerging importance in the fields of astrophysics, nanoscience and neuroscience. The Frontiers of Science symposia bring together some of the very best young scientists across many disciplines to share and discuss exciting advances and opportunities in their fields. Videos and feature pieces have been created for teachers and students. This includes video interviews with acclaimed researchers Eric Kandel, M.D. and Edvard and May-Britt Moser, a video introduction and panel discussion on neuroscience, feature stories, written science overview, institute profiles and other materials. The Kavli Foundation is a private foundation qualified under IRC Section 501 (c) (3).

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• 15 years ago - by Anonymous

The HFSP supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms; topics range from molecular and cellular approaches to systems and cognitive neuroscience. A clear emphasis is placed on novel collaborations that bring biologists together with scientists from fields such as physics, mathematics, chemistry, computer science and engineering to focus on problems at the frontier of the life sciences. The Trust provides funding for research regarding complex biological systems. It offers research grants, post doc fellowships, career development fellowships, and short- long- and cross- disciplinary fellowships. HFSP funding programs are strictly project-related and begin at the postdoctoral level. We have no support for PhD students nor for travel grants to scientific meetings. Nor do we provide sponsorship or funds to organizers of scientific meetings. Research Grants Research Grants are awarded for novel collaborations involving extensive collaboration among teams of scientists working in different countries and in different disciplines. Two types of grants are available: Young Investigators Grants and Program Grants. Postdoctoral Fellowships Postdoctoral Fellowships are available for scientists who wish to work in foreign laboratories, with emphasis on individuals early in their careers who wish to obtain training in a different field of research. Fellows who return to their home countries or move to an HFSP member country that is different from the Fellowship host country are eligible to apply for a Career Development Award. Long-Term Fellowships are for scientists with a Ph.D. degree in the life sciences who wish to broaden their experience through postdoctoral training abroad. Cross-Disciplinary Fellowships are intended for postdoctoral fellows with a Ph.D. degree in the physical sciences, chemistry, mathematics, engineering and computer sciences who wish to receive training in biology. Career Development Awards Career Development Awards are for former HFSP Long-Term or Cross-Disciplinary Fellows who return to their home country or move to an HFSP member country that is different from the host country of their HFSP Fellowship. The award provides support for initiating the fellows'' first independent laboratory., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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The Leona M. and Harry B. Helmsley Charitable Trust supports a broad spectrum of healthcare and medical research-based programs. The areas supported include Type 1 Diabetes, Digestive Diseases, Rural Healthcare, Cardiology, and a range of other programs and institutions.

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• 15 years ago - by Anonymous

RNA-seq tool that uses the Dirichlet distribution and a transformation to identify genes that exhibit small within-condition and large between-condition variance.

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• SciCrunch
• 13 years ago - by Anonymous

Software for somatic single nucleotide variant (SNV) and small indel detection from sequencing data of matched tumor-normal samples. Strelka2 germline and somatic small variant caller.

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• 13 years ago - by Anonymous

Software program to identify single nucleotide positions that are different between tumor and normal (or, in theory, any two bam files). It takes a tumor bam and a normal bam and compares the two to determine the differences. It outputs a file in a format very similar to Samtools consensus format. It uses the genotype likelihood model of MAQ (as implemented in Samtools) and then calculates the probability that the tumor and normal genotypes are different. This probability is reported as a somatic score. The somatic score is the Phred-scaled probability (between 0 to 255) that the Tumor and Normal genotypes are not different where 0 means there is no probability that the genotypes are different and 255 means there is a probability of 1 ? 10(255/-10) that the genotypes are different between tumor and normal. This is consistent with how the SAM format reports such probabilities. It is currently available as source code via github or as a Debian APT package.

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• SciCrunch
• 13 years ago - by Anonymous

Tool for calling indels in Tumor-Normal paired sample mode.

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• 13 years ago - by Anonymous