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Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, and ongoing research that helps us better understand and treat disorders. Mental disorders are common. You may have a friend, colleague, or relative with a mental disorder, or perhaps you have experienced one yourself at some point. Such disorders include depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), and many others. Some people who develop a mental illness may recover completely; others may have repeated episodes of illness with relatively stable periods in between. Still others live with symptoms of mental illness every day. They can be moderate, or serious and cause severe disability. Through research, we know that mental disorders are brain disorders. Evidence shows that they can be related to changes in the anatomy, physiology, and chemistry of the nervous system. When the brain cannot effectively coordinate the billions of cells in the body, the results can affect many aspects of life. Scientists are continually learning more about how the brain grows and works in healthy people, and how normal brain development and function can go awry, leading to mental illnesses. Brain Basics will introduce you to some of this science, such as: * How the brain develops * How genes and the environment affect the brain * The basic structure of the brain * How different parts of the brain communicate and work with each other * How changes in the brain can lead to mental disorders, such as depression.

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• SciCrunch
• 15 years ago - by Anonymous

Software for analyzing and visualization of the results of deep amplicon sequencing.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step.

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• SciCrunch
• 13 years ago - by Anonymous

The NIH Office of Science Education (OSE) coordinates science education activities at the NIH and develops and sponsors science education projects in house. These programs serve elementary, secondary, and college students and teachers and the public. Activities * Develop curriculum supplements and other educational materials related to medicine and research through collaborations with scientific experts at NIH * Maintain a website as a central source of information about NIH science education resources * Establish national model programs in public science education, such as the NIH Mini-Med School and Science in the Cinema * Promote science education reform as outlined in the National Science Education Standards and related guidelines The OSE was established in 1991 within the Office of Science Policy of the Office of the Director of the National Institutes of Health. The NIH is the world''s foremost biomedical research center and the U.S. federal government''s focal point for such research. It is one of the components of the Department of Health and Human Services (HHS). The Office of Science Education (OSE) plans, develops, and coordinates a comprehensive science education program to strengthen and enhance efforts of the NIH to attract young people to biomedical and behavioral science careers and to improve science literacy in both adults and children. The function of the Office is as follows: (1) develops, supports, and directs new program initiatives at all levels with special emphasis on targeting students in grades kindergarten to 16, their educators and parents, and the general public; (2) advises NIH leadership on science education issues; (3) examines and evaluates research and emerging trends in science education and literacy for policy making; (4) works closely with the NIH extramural, intramural, women''s health, laboratory animal research, and minority program offices on science education special issues and programs to ensure coordination of NIH efforts; (5) works with NIH institutes, centers, and divisions to enhance communication of science education activities; and (6) works cooperatively with other public- and private-sector organizations to develop and coordinate activities.

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• SciCrunch
• 15 years ago - by Anonymous

Software tool for biomarker assessment and outcome based cut point optimization.

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• SciCrunch
• 13 years ago - by Anonymous

Open-source software to support information and images related to tissue micro-arrays. It contains support for multiple organ systems, multiple users, image analysis, and is designed to be compliant with HIPPA regulations. Patients, specimens, blocks, slides, cores, images, and scores can all be stored and viewed. Features include advanced security, custom dynamic fields, and an image analysis program.

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• SciCrunch
• 13 years ago - by Anonymous

A Simple Software Tool to Permit Analysis of Replicate Cores on Tissue Microarrays., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 13 years ago - by Anonymous

A free web-based service open to all users for analysis of tissue microarray (TMA) data and related information, accommodating categorical, semi-continuous and continuous expression scores. There is no login requirement.

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• SciCrunch
• 13 years ago - by Anonymous

Software Tools for High-Throughput Analysis and Archiving of Immunohistochemistry Staining Data Obtained with Tissue Microarrays.

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• SciCrunch
• 13 years ago - by Anonymous

A high performance, intuitive client viewer with integrated reporting functionality that can be used as a standalone viewer for accessing slides locally, or connected to Digital Image Hub for remote review.

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• SciCrunch
• 13 years ago - by Anonymous

Tissue microarray (TMA) Software used for Biomarker Discovery that allows TMA experiments to be performed anytime, anywhere, reducing administrative costs and time. It is designed to support TMA scoring workflow and allows configuration of experiments in minutes. Access and view clinical metadata, the TMA core, scoring criteria and the TMA map all on a single interface.

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• SciCrunch
• 13 years ago - by Anonymous

A web-based application for the management and storage of tissue microarray (TMA) images and the associated metadata. The application enables the user to navigate a grid of TMA core images within a slide, zoom and pan around an image, and enter a score constrained to a specific scoring system. The submitted scores are scored in the eXist open source database, in an XML format, which is compatible with existing TMA standards, and thus allow the data to be archived and re-used in future analysis.

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• SciCrunch
• 13 years ago - by Anonymous

A provider for videos available from the National Institute of Mental Health (NIMH). Visitors may sort by topic and/or subscribe to RSS feeds.

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• SciCrunch
• 15 years ago - by Anonymous

A web-based software package for comparative genomics.

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• SciCrunch
• 13 years ago - by Anonymous

Learn About SMA is a resource for spinal muscular atrophy (SMA) patients, families and researchers. The site includes stories of living with SMA and recent advances in the understanding and potential treatment of SMA. Learn About SMA is divided into five sections with video interviews, animations, and narrative. What is SMA? includes interviews with doctors and patients, plus an animation explaining the cause, inheritance and diagnosis of SMA. SMA Science provides an introduction to the genes and mechanisms involved with SMA, including 2-D and 3-D animations and interviews with Nobel Laureates. * In SMA Therapies doctors discuss current and potential treatments for SMA and a father describes the daily routine of physical therapies for his daughter, who has SMA. Antisense Therapy for SMA includes videos and animations to explain antisense therapy for SMA. In Living with SMA four SMA families describe daily routines, disease progression, children''s understanding of SMA, and grieving.

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• SciCrunch
• 15 years ago - by Anonymous

A suite of programs aimed at developers of alignment methods rather than end-users to assess the accuracy of multiple sequence alignment methods. It includes a reference database of protein multiple sequence alignments that were generated by consideration of protein three-dimensional structure.

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• SciCrunch
• 13 years ago - by Anonymous

Our hope and aims are to empower those affected by common life difficulties such as Anxiety, Depression, low Self-Esteem etc to overcome their obstacles and achieve their full and true potential. Our core approach is client-centred and we aim to convey to each client the ''core conditions'' of empathy, congruence and unconditional positive regard. Using Compassion focused Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT) among other approaches we gear all therapy treatments towards clients unique needs and goals. Passionate about research in all therapeutic and associated fields, we want to continue to keep our fingers on the pulse of developments in this area of work. We at Solve Therapies strive to empower all of our clients to choose helpful, rational thoughts and actions and to do so with less shame and self-criticism through the use of Cognitive Behavioural Therapy and Compassion-focused techniques. We offer a confidential, professional therapeutic service using Cognitive Behavioural Therapy and other forms of counseling/psychotherapy. All therapists are accredited and regulated by the British Association of Counselling & Psychotherapy (BACP) and/or British Association of Behavioural and Cognitive Psychotherapy (BABCP), the professional bodies who regulate, inform and ensure ethical practice. We also provide useful information on common difficulties and on how you can learn how to become your own therapist and manage your difficulties in the long term, with counselling venues throughout Northern Ireland including Belfast, Portrush, Antrim and Portglenone in order to provide flexibility for client appointments. ''''''S''''''olution-focused ''''''O''''''ptions ''''''L''''''ife-change ''''''V''''''alidation ''''''E''''''mpathy

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• SciCrunch
• 15 years ago - by Anonymous

A comparative pathology unit offering pathology support, training programs, and a Tissue Distribution Program (TDP). The TDP provides a wide variety of nonhuman primate tissues to investigative groups within and outside the Washington National Primate Research Center (WaNPRC). Tissue and pathology services (ACVP board certified Veterinary Pathologists), full histology services (including immunohistochemistry and frozen sectioning), and protocol development consultation are available. The Pathology and Tissue Program is an integration of comparative pathology activities occurring at the Washington National Primate Research Center and those occurring within the University of Washington Department of Comparative Medicine ((DCM). Using this model, Washington National Primate Research Center pathologists provide routine pathology support for Washington National Primate Research Center animals, with ancillary support, expertise, and guidance provided by DCM pathologists and mission-dedicated technicians and laboratories. This integrated comparative pathology unit also provides an excellent training opportunity for students such as those enrolled in the Department of Comparative Medicine post-doctoral training program, which offers training in laboratory animal medicine and comparative pathology. A particularly important function of this comparative pathology unit is support of the Tissue Distribution Program. The TDP provides a wide variety of nonhuman primate tissues to investigative groups within and outside the WaNPRC. This program is an extremely valuable method of conserving the nonhuman primate resource. NHP tissues and biological materials are collected in preparation for RNA/DNA isolation, cell culture, immunohistochemistry/histology, anatomic dissection, and cell sorting. Capabilities of the TDP include, but are not limited to flash frozen preservation, sterile preparation, perfusion, technical surgical dissections, and OCT embedding. In conjunction with the Histology and Imaging core of the University of Washington DCM, research capabilities post-collection include in situ hybridization, confocal and fluorescent microscopy, live cell imaging (DeltaVision), and whole slide scanning with image analysis (Visiopharm, Nikon Elements, and Image Pro). Centralized coordination of nonhuman primate tissue requests with animal availability allows support for a large number of biomedical programs with significantly decreased impact on the animal resource.

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• SciCrunch
• 15 years ago - by Anonymous

Database of photographs and illustrations of general biomedical research and research tools, mental health specific research, and treatment related images that are available, copyright free, to the public at no cost. Many images are available in low, medium, and high resolutions. Formats include jpg, gif, and png. NIMH images may not be used to state or imply the endorsement by NIMH or by an NIMH employee of a commercial product, service, or activity, or use in any other manner that might mislead. No fee is charged for using the images. However, credit must be given to the National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services unless otherwise instructed to give credit to the photographer or other source., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 15 years ago - by Anonymous

A software package in Mesquite that processes chromatograms, makes contigs, base calls, etc., using in part the programs Phred and Phrap.

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• SciCrunch
• 13 years ago - by Anonymous