Curator Dashboard

An ontology including concepts, definitions, terms, and resources for a standardized description of a microarray experiment in support of MAGE v.1. The MGED ontology is divided into the MGED Core ontology which is intended to be stable and in synch with MAGE v.1; and the MGED Extended ontology which adds further associations and classes not found in MAGE v.1. These terms will enable structure queries of elements of the experiments. Furthermore, the terms will also enable unambiguous descriptions of how the experiment was performed.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

A publicly-accessible website to measure and visualize similarities and differences between molecular profiles of complex microbial communities. The project includes visualization tools such as heat maps that simultaneously compare the taxonomic distributions of multiple datasets and 3-D charts of the frequency distributions of 16S rRNA tags. Analytical tools include Chao diversity estimates and rarefaction curves. As a service to the community, researchers have the opportunity to upload their own data to the site for private viewing with the full range of data and analysis tools. Public data can be downloaded for further analysis locally.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Database of neurobehavioral and physiological data of adult zebrafish models, complementing the available repositories for zebrafish genetic information, by providing a dynamic, open-access data repository of comprehensive, curated collection of results from zebrafish neurobehavioral experiments. As of May 2012, it contains over 4,500 experimental results, from over 75 unique physiological and behavioral tests and 330 different drug treatments. ZNP incorporates validated and curated data from work published in this field, to improve the accessibility of current knowledge to researchers interested in using adult zebrafish models. Overall, this program will allow investigators to rapidly review data, to direct their research using these models. Data and protocol submissions are now being accepted.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

While many data sharing programs exist worldwide, widespread sharing of raw data has not yet won across-the-board acceptance in the scientific community, and the very existence of all these databases makes the approach fractured at best. The Data Sharing Project, launched last year by University of California-San Francisco Professor Michael Weiner, has two goals: One is to make widespread raw data sharing a reality initially in the realm of medicine through creation of a repository system accessible to all researchers; the second goal is to foster broad scientific support for this move and its adoption in other fields of research. With major projects such as the Human Genome Project demonstrating the tremendous scientific breakthroughs made possible by data sharing and with the decline of technological barriers impeding such efforts, the time has come to work to achieve widespread sharing of raw data worldwide. The Data Sharing Project proposes to further this goal initially in the field of medicine by working to create a raw data sharing program that will serve as a model to other disciplines attempting to make their own way in this arena. The Northern California Institute for Research and Education (NCIRE) together with the University of California-San Francisco and support from the Michael J. Fox Foundation is now in the process of canvassing the scientific community to analyze the best possible data sharing program and practices to establish in the field of medicine.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Expression pattern map of the 100Mb genome of the nematode Caenorhabditis elegans through EST analysis and systematic whole mount in situ hybridization. NEXTDB is the database to integrate all information from their expression pattern project and to make the data available to the scientific community. Information available in the current version is as follows: * Map: Visual expression of the relationships among the cosmids, predicted genes and the cDNA clones. * Image: In situ hybridization images that are arranged by their developmental stages. * Sequence: Tag sequences of the cDNA clones are available. * Homology: Results of BLASTX search are available. Users of the data presented on our web pages should not publish the information without our permission and appropriate acknowledgment. Methods are available for: * In situ hybridization on whole mount embryos of C.elegans * Protocols for large scale in situ hybridization on C.elegans larvae

• Resource
• SciCrunch
• 16 years ago - by Anonymous

SysMO-DB is a project that is creating a web-based platform, and tooling, for finding, sharing and exchanging Data, Models and Processes in Systems Biology. It was designed to support the SysMO Consortium (Systems Biology for Micro-Organisms), but the principles and methods employed are equally applicable to other multi-site Systems Biology projects. All code is open source and available for download. SEEK, a component of SysMO-DB, is a private community collaboration and asset sharing platform for Systems Biology models, data and protocols serving 120 research institutions throughout Europe. SEEK is the main web-based access point to the system and provides an access control layer to enable researchers to restrict access to collaborators, colleagues or other individuals until they are ready to share with the whole consortium or the wider community. The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that: * facilitates and maximizes the potential for data exchange between SysMO research groups; * maximizes the ''shelf life'' and utility of data generated by SysMO; * provides an integrated platform for the dissemination of the results of the SysMO projects to the scientific community; and * facilitates standardization of practices in Systems Biology for the interfacing of modeling and experimentation. We follow several key principles: * exploit what is already available, both within the consortium and outside it, and do not reinvent; * identify the least we can do to make a benefit and do this incrementally. SysMO-DB will soon be opening it up to the wider scientific community, but for now it is currently only available for those within the SysMO consortium.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented September 6, 2016.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

NEWT is the taxonomy database maintained by the UniProt group. It integrates taxonomy data compiled in the NCBI database and data specific to the UniProt Knowledgebase. Browse by hierarchy, List all, or Complete proteomes. Organisms are classified in a hierarchical tree structure. Our taxonomy database contains every node (taxon) of the tree. UniProtKB taxonomy data is manually curated: next to manually verified organism names, we provide a selection of external links, organism strains and viral host information. Species with protein sequences stored in the UniProt Knowledgebase are named according to UniProt nomenclature. We endeavour to maintain a list of manually curated species names for which protein sequence data is available. In particular, we have adopted a systematic convention for naming viral and bacterial strains and isolates. Links to external sites are chosen by the UniProt taxonomy team and show pictures and various scientific data of interest (taxonomy, biology, physiology,...).

• Resource
• SciCrunch
• 16 years ago - by Anonymous

An accredited cord blood bank and stem cell bank in Europe. Services offered include family cord blood banking, public banking, directed allogeneic transplantation, umbilical cord tissue banking and HLA typing.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Public database of information about all clinical trials involving humans, this global initiative provides a single point of access to information about ongoing and completed clinical trials. It contains the trial registration data sets made available by data providers around the world meeting criteria for content and quality control. It also aims to: * To improve the comprehensiveness, completeness and accuracy of registered clinical trial data * To communicate and raise awareness of the need to register clinical trials * To ensure the accessibility of registered data * To build capacity for clinical trial registration * To encourage the utilization of registered data * To ensure the sustainability of the ICTRP The mission of the WHO International Clinical Trials Registry Platform is to ensure that a complete view of research is accessible to all those involved in health care decision making. This will improve research transparency and will ultimately strengthen the validity and value of the scientific evidence base. The registration of all interventional trials is a scientific, ethical and moral responsibility. The ICTRP: * Publishes the ICTRP Search Portal * Supports the WHO Registry Network * Supports countries and regions wanting to establish WHO-compliant clinical trial registries or policies on trial registration.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

WikiHealthCare is The Joint Commission''s interactive forum for health care professionals. It is designed to enable and encourage discussion and collaboration among all users for the purpose of improving health care quality. While The Joint Commission provides the forum, users of the site control its content. The WikiHealthCare Quality Improvement forum is a collaborative network for health care professionals, researchers, and other health care stakeholders. Within this forum, you can freely exchange information, describe your implementation experiences and create and share performance improvement solutions. Registered members of the WikiHealthCare community are free to use this forum to create new web pages, initiate blogs, and dialogue with other members of the community.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Intergovernmental organisation funded by public research money from its member states in Europe. Groups and laboratories perform basic research in molecular biology and molecular medicine, training for scientists, students and visitors. Provides development of services, new instruments and methods, data and technology in its member states.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Infrastructure for sharing cardiovascular data and data analysis tools. Human ExVivo heart data set and canine ExVivo normal and failing heart data sets are available. Canine hearts atlas and human InVivo atlases are available.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The center is usually called Roswell Park in short.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

The Feinstein Institute for Medical Research is the research branch of the North Shore-Long Island Jewish Health System. Biomedical research has been a vital aspect of its two academic medical centers North Shore University Hospital and Long Island Jewish Medical Center since their establishment in the early 1950''s. Through its connection to the hospital system, the Institute bridges the gap between biomedical research and patient care, accessing hundreds of thousands of patients in the health system''s 15 hospitals, four long-term care facilities, three trauma centers, six home health agencies and dozens of outpatient facilities. Institute scientists collaborate with clinicians throughout the system to shed light on basic biological processes underlying disease. This knowledge is used to develop new therapies and diagnostics. Currently, more than 800 scientists and investigators are conducting research in oncology, immunology and inflammation, genetics, psychiatry, neurology, pediatrics, surgery, urology, obstetrics/gynecology and many other specialties. In 2008, the Feinstein received funding from the National Institutes of Health in excess of $28 million, and an additional $10 million from other federal sources. Total annual research funding from all sources exceeded $44 million in 2008. We stand at the threshold of an extraordinary time in medicine. Over the last 100 years, biomedical science has progressed very rapidly. Advances coming from the integration of genomics, proteomics and bioinformatics into the biomedical toolkit hold the promise that this transformation will continue well into the 21st century. The Feinstein Institute for Medical Research is a growing force in research innovation, education and progress.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

A set of tools to facilitate analysis of alternative splicing from RNA-SEQ data.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Cureline BioPathology is a research histology laboratory providing high-quality human and animal tissue processing, preparation and analysis. In collaboration with Cureline, Cureline BioPathology offers a complete portfolio of services in human tissue research, including human tissue acquisition, biospecimen storage, tissue processing and comprehensive tissue analysis using special stains and immunohistochemical methods. The laboratory was founded in San Francisco Bay area by Cureline, Inc., to leverage already established relationships with clinical sites and biotechnology companies. Cureline has extensive experience in human tissue procurement, preservation and biospecimen management, and has been providing effective human tissue research services to pharmaceutical and biotechnology clients since 2003. Our experienced and motivated team is dedicated to providing support to academia and industry clients in all aspects of human and animal tissue processing, target profiling, antibody cross-reactivity studies, and toxicology.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

The Estonian Biobank is the population-based biobank of the EGCUT. The project is conducted in accordance with the Estonian Genes Research Act and all participants have signed a broad informed consent form (www.biobank.ee <http://www.biobank.ee/> and Metspalu 2004, Drug Dev. Res.). As of December 2011, the biobank contains 51,515 participants (gene donors). The database of genotypic, phenotypic, health and genealogical information represents about 5% of Estonia''s adult population, and is the largest cohort ever gathered in Estonia. The age, sex and geographical distribution of this cohort reflect the structure of the adult population in Estonia. The database enables to conduct research in order to find links between genes, environmental factors, lifestyles and complex diseases or other traits. Active use of the biobank has started and although the first users are researchers all over the world with hundreds of different projects currently underway, industry is also interested. At the international level, the EGCUT will join the BBMRI follow-up program (ERIC) and through this channel provide service (biobanking, genotyping, sequencing and data analysis) for the centers in Europe who need it. Currently, the first follow-up study is underway and the molecular information of the cohort will be increased. For example, we have over 12 000 DNA samples analyzed by high density genotyping arrays and over 10 000 plasma samples analyzed by NMR scans, over 1000 individuals with RNA expression arrays, 2000 individuals with clinical laboratory analysis (over 40 tests) and over 60 full genomes are under deep sequencing. The infrastructure of the EGCUT includes a laboratory for DNA genotyping and next generation sequencing all based on Illumina platforms (HiScanSQ, HiSeq2000 and robotics), an IT unit (databases) with required computing power and storage space (1.2PB), data analysis team (bioinformatics and statistical genetics) and last but not least, a patient recruitment unit (health records, lifestyle and environmental information and biological samples ����?����������?? DNA, plasma and WBC from all 51515 gene donors). This is all located on 1000m2 in a brand new laboratory building, Riia str 23, Tartu, Estonia.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

The Neuroscience Program at Iowa State University has a philosophy based on the balanced combination of mentoring, general curriculum and frontier collaborative research to teach graduate students essential theoretical, research, teaching, writing and presentation skills and to prepare students for the competitive environment in academia and industry. The program reflects the structure of contemporary neuroscience which has become a diverse and inter-disciplinary field. Students of diverse educational, ethnic and national backgrounds are encouraged to apply to the program. Participating Departments in Neuroscience * Animal Science * Biochemistry, Biophysics and Molecular Biology * Biomedical Sciences * Chemical and Biological Engineering * Chemistry * Computer Science * Genetics, Development and Cell Biology * Kinesiology * Psychology

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Through the South Dakota Lions Eye Bank, donors can provide the gift of sight and health through the donation of bone, connective tissue, heart valves, veins, skin, and corneas. The option of donation is available to both men and women, up to the age of 95. Since 1990, the South Dakota Lions Eye Bank has restored sight to over 5500 people world wide. In recent statistics the South Dakota Lions Eye Bank has transplanted 2217 corneas since 2001; 1237 transplanted in the United States and 980 transplanted overseas. It is the fondest hope of the South Dakota Lions Eye Bank that you will become an eye, tissue and organ donor and pass along to someone the greatest gift of all, Life.

• Resource
• SciCrunch
• 16 years ago - by Anonymous