Curator Dashboard

Freely available tool for Gene-centered collection and display of DNA variations. It also provides patient-centered data storage and storage of Next Generation Sequencing (NGS) data, even of variants outside of genes. Please note that LOVD provides a system for storage of information on genes and allelic variants. To obtain information about any genes or variants, do not download the LOVD package. This information should be obtained from the respective databases, http://www.lovd.nl/2.0/index_list.php In total: 2,507,027 variants (2,208,937 unique) in 170,935 individuals in 62619 genes in 88 LOVD installations. (Aug. 2013) LOVD 3.0 shared installation, http://databases.lovd.nl/shared/genes To maintain a high quality of the data stored, LOVD connects with various resources, like HGNC, NCBI, EBI and Mutalyzer. You can download LOVD in ZIP and GZIPped TARball formats.

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• SciCrunch
• 17 years ago - by Anonymous

An online open-access open-data journal, publishing ''big-data'' studies from the entire spectrum of life and biomedical sciences whose publication format links standard manuscript publication with its affiliated database, GigaDB, that hosts all associated data, provides data analysis tools, cloud-computing resources, and a DOI assignment to every dataset. GigaScience covers not just ''omic'' type data and the fields of high-throughput biology currently serviced by large public repositories, but also the growing range of more difficult-to-access data, such as imaging, neuroscience, ecology, cohort data, systems biology and other new types of large-scale sharable data. Supporting the open-data movement, they require that all supporting data and source code be publicly available in a suitable public repository and/or under a public domain CC0 license in the BGI GigaScience database. Using the BGI cloud as a test environment, they also consider open-source software tools / methods for the analysis or handling of large-scale data. When submitting a manuscript, please contact them if you have datasets or cloud applications you would like them to host. To maximize data usability submitters are encouraged to follow best practice for metadata reporting and are given the opportunity to submit in ISA-Tab format.

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• SciCrunch
• 16 years ago - by Anonymous

We at NRSP-8 bioinformatics coordination program strive to serve the animal genomics research community to better use computer tools and methods, to best utilize available resources, and in working with researchers in the community, to effectively share, combine, manage, manipulate, and analyze information from genomics/genetics studies. This site is designed as an information center to serve the national animal genome research projects of cattle, chicken, pigs, sheep, horse, and aquaculture species. This is home to databases and web sites (being) built for structural, functional and application oriented studies of the animal genomics, to serve the purpose of research, education and related activities in the scientific, industrial and educational communities in the states and world wide. The challenges in bioinformatics support/research for animal genomics may involve * Effective data collection, organization and management * Rapid development of most needed bioinformatics tools and resources * Efficient use of these tools for innovative data analysis Projects: * Animal Trait Ontology (ATO) Project * Virtual Comparative Genomics * The Past, the Current, and the Potentials * Collaborative and Hosted Works

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• SciCrunch
• 15 years ago - by Anonymous

ViralZone is a SIB Swiss Institute of Bioinformatics web-resource for all viral genus and families, providing general molecular and epidemiological information, along with virion and genome figures. Each virus or family page gives an easy access to UniProtKB/Swiss-Prot viral protein entries. ViralZone project is handled by the virus program of SwissProt group. Proteins popups were developed in collaboration with Prof. Christian von Mering and Andrea Franceschini, Bioinformatics Group , Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland, funded in part by the SIB Swiss Institute of bioinformatics. All pictures in ViralZone are copyright of the SIB Swiss Institute of Bioinformatics.

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• SciCrunch
• 15 years ago - by Anonymous

Our mission is to conduct fundamental research in the areas of cell biology, developmental biology and neurobiology, and to provide a first rate educational experience for students of the Medical College of Wisconsin and its Graduate School of Biomedical Sciences. Current research in the department is strong in two major areas; developmental biology and neurobiology. Postdoctoral research opportunities are available. In developmental biology there is a focus on growth, regeneration and transcription mediated pathways in such systems as neural crest differentiation, heart development, liver development and in the area of muscle atrophy and plasticity. In neurobiology there is a strength in vision with special focus on photoreceptor cell biology, color vision, plasticity in the visual cortex, and functional MRI of the visual system. The department is currently expanding its research efforts in both areas. Faculty in the department also participate in interdisciplinary graduate education through the Graduate Programs in Neuroscience and Biomedical Sciences, and through management of an interdisciplinary Graduate Program in Cell and Developmental Biology. The department also plays an essential role in medical education through its first year medical courses in Cell and Tissue Biology, Developmental Biology, and Clinical Human Anatomy. In addition, the department is a principal participant in an interdisciplinary neuroscience course which includes faculty from other departments within the medical college.

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• SciCrunch
• 17 years ago - by Anonymous

eMedicineHealth.com is a consumer health information site that was launched in May 2003. The site contains over 900 health and medical articles written by physicians for patients and consumers. If you are interested in authoring one or more articles, or if you are interested in becoming a medical editor for eMedicineHealth, please see our Medical Writer and Medical Editor submission form for more information. You may search for information or use the Topics from A-Z option. Additionally, Slideshow pictures, Image gallery, Medications, Quizzes, and Medical Dictionary sections are available. eMedicineHealth.com''s main office is in San Clemente, California, and the corporate office is in New York, New York.

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• SciCrunch
• 16 years ago - by Anonymous

Provides clinically relevant and medically actionable information for inherited conditions in standardized journal-style format, covering diagnosis, management, and genetic counseling for patients and their families. Searchable book of expert-authored, peer-reviewed disease descriptions presented in standardized format and focused on clinically relevant and medically actionable information on diagnosis, management, and genetic counseling of patients and families with specific inherited conditions.

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• SciCrunch
• 13 years ago - by Anonymous

Software to harmonize the data that you have in different Excel files, databases, repositories, biospecimen applications, etc. and maps it to one common registry. Remedy Informatics' platform aggregates data from multiple sources, harmonizes the data via Ontology, and provides data visualization and pattern recognition and querying tools.

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• SciCrunch
• 13 years ago - by Anonymous

Prize4Life is a 501(c)(3) nonprofit organization dedicated to accelerating the discovery of treatments and cures for ALS (amyotrophic lateral sclerosis, also known as Lou Gehrig''s disease). Our mission is to accelerate the discovery of a treatment and a cure for ALS by using powerful incentives to attract new people and new ideas and to leverage existing efforts and expertise in the ALS field. Our Values: * Patients first. Avichai Kremer, one of the Harvard Business School students who founded Prize4Life, was diagnosed with ALS in 2004. We therefore know the disease firsthand and have a sense of urgency to find a treatment. We value patients and their viewpoints. Patients, please tell us what you think. * Global awareness. We plan to push ALS to the forefront of fatal disease issues. We need your help in order to do this. Get involved. * New people and new ideas. We believe important breakthroughs in ALS may reside in the minds and laboratories of people who are not currently researching the disease. Our platform is a bridge for reaching these people. Enter the competition. * Results. Research is traditionally funded upfront, before an idea is even tested. Our prize model ensures that only clear research results, vetted by a team of scientific advisors, are rewarded. grants; funding resource;.

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• SciCrunch
• 17 years ago - by Anonymous

Standard Windows interoperability suite of programs for Linux and Unix that provides secure, stable and fast file and print services for all clients using the SMB/CIFS protocol, such as all versions of DOS and Windows, OS/2, Linux and many others. Samba is an important component to seamlessly integrate Linux/Unix Servers and Desktops into Active Directory environments using the winbind daemon.

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• SciCrunch
• 13 years ago - by Anonymous

The Neurotechnology Industry Organization (NIO) is a non-profit trade association that represents companies involved in neuroscience (neuropharmaceuticals, cell-based therapeutics, neurodevices and neurodiagnostics), academic neuroscience research centers, and brain-illness advocacy groups across the United States and throughout the world. NIO was formed to provide a unified voice for the commerical neuroscience community. NIO advocates for its member organizations on a range of issues related to neurotechnology research and business development including favorable changes in the tax code, intellectual property issues, neuroethics, public policy, reimbursement and patient advocacy. Thank you for taking the time to read this brief introduction to the Neurotechnology Industry Organization (NIO), the recently formed trade association representing companies involved in neuroscience (drugs, devices and diagnostics), brain research centers, patient advocacy groups, and research foundations worldwide. NIO was founded in August 2006 and has attracted over 80 member organizations. NIO''s mission is to accelerate treatments and cures for brain and nervous system illnesses by: * Advocating neurotech''s position to government and regulatory officials * Promoting the industry''s progress and contributions to quality of life * Providing industry development services for our members NIO is spearheading several innovative programs that will benefit your company including: National Neurotechnology Initiative - a new $200M/year Federal initiative aimed at accelerating translational neuroscience innovation and improving the effectiveness of the FDA review process for neuroscience drugs, devices and diagnostics NIO/FDA private-public working group - an initiative to work collaboratively with the FDA to improve the efficiency of the evaluation process for neuroscience products and to increase communication and clarity during the regulatory process Partnering, investment and policy events - networking events with other members of the global commercial neuroscience community at events such as the annual public policy tour in March in Washington D.C. and the Neurotech investing and partnering conference in Spring National Visibility - NIO actively outreaches to global media outlets to encourage coverage of Neurotech that will foster great investor, policymaker and consumer interest. As a member of NIO you will enjoy the following benefits: * Influence in the industry''s overall development agenda * Access to key opinion leaders in Congress, regulatory agencies, media * Participation in FDA and CMS working groups, stakeholder meetings * Expanded networking at neurotech investing and partnering events throughout the year * Participation in neuroscience education awareness initiatives, public awareness campaigns * Industry leadership through participation in driving innovative legislation, new projects NIO''s programs increase awareness of commercial neuroscience products, reduce barriers to innovation, support industry growth and will benefit your company and industry. I hope that you will consider joining NIO in support of our mission to give the brain a voice..

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• SciCrunch
• 17 years ago - by Anonymous

Public global Protein Data Bank archive of macromolecular structural data overseen by organizations that act as deposition, data processing and distribution centers for PDB data. Members are: RCSB PDB (USA), PDBe (Europe) and PDBj (Japan), and BMRB (USA). This site provides information about services provided by individual member organizations and about projects undertaken by wwPDB. Data available via websites of its member organizations.

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• SciCrunch
• 15 years ago - by Anonymous

An NIH office devoted to the study of the role of behavioral and social factors in illness and health. Its mission is to stimulate behavioral and social sciences research throughout NIH and to integrate these areas of research more fully into others of the NIH health research enterprise, thereby improving our understanding, treatment, and prevention of disease. To provide the OBSSR with counsel in fulfilling its mission, the Behavioral and Social Sciences Research Coordinating Committee (BSSR CC) serves as an internal advisory board. The Office of Behavioral and Social Sciences Research (OBSSR) opened officially on July 1, 1995. The major responsibilities of the office and its director, set forth in its formal mission statement, are: * To provide leadership and direction in the development, refinement, and implementation of a trans-NIH plan to increase the scope of and support for behavioral and social sciences research. * To inform and advise the NIH director and other key officials of trends and developments having significant bearing on the missions of the NIH, DHHS, and other federal agencies. * To serve as the principal NIH spokesperson regarding research on the importance of behavioral, social, and lifestyle factors in the causation, treatment, and prevention of diseases; and to advise and consult on these topics with NIH scientists and others within and outside the federal government. * To develop a standard definition of behavioral and social sciences research, assess the current levels of NIH support for this research, and develop an overall strategy for the uniform expansion and integration * of these disciplines across NIH institutes and centers. * To develop initiatives designed to stimulate research in the behavioral and social sciences arena, integrate a bio-behavioral perspective across the research areas of the NIH, and encourage the study of behavioral and social sciences across NIH''s institutes and centers. * To initiate and promote studies to evaluate the contributions of behavioral, social, and lifestyle determinants in the development, course, treatment, and prevention of illness and related public health problems. * To provide leadership in ensuring that findings from behavioral and social sciences research are disseminated to the public. * To sponsor seminars, symposia, workshops, and conferences at the NIH and at national and international scientific meetings on state-of-the-art behavioral and social sciences research. Funding Opportunities Announcements (FOA) Since opening its doors in 1995, The Office of Behavioral and Social Sciences Research (OBSSR) has worked to achieve the goals of its authorizing legislation by effectively highlighting and supporting the scientific opportunities that exist in basic and applied behavioral and social sciences research. Guided by its Strategic Plan, OBSSR has been working actively with its IC partners to develop funding opportunities in the behavioral and social sciences. Although OBSSR does not have grant-making authority, it has been active in organizing and funding (through transfers to NIH Institutes and Centers) a variety of trans-NIH research programs. Scientific Areas The Office of Behavioral and Social Sciences Researchs (OBSSR) leadership is crucial at a time when exciting scientific opportunities, persistent public health needs, and emergent public health challenges face our nation. The vision of the office is to bring together the biomedical, behavioral, and social science communities to work more collaboratively to solve complex pressing health challenges. Notable areas of research where OBSSR has led efforts and encourages research include: * Biopsychosocial Interactions * Methodology (including Systems Science and CBPR) * Genes, Behavior and Environment * Social and Cultural Factors in Health * Health and Behavior * Translation OBSSR Training & Education Opportunities The Office of Behavioral and Social Sciences Research (OBSSR) develops and coordinates training and career development opportunities with the NIH Institutes and Centers.

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• SciCrunch
• 17 years ago - by Anonymous

Consortium that puts sequences into a chromosome context and provides the best possible reference assembly for human, mouse, and zebrafish via FTP. Tools to facilitate the curation of genome assemblies based on the sequence overlaps of long, high quality sequences.

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• SciCrunch
• 17 years ago - by Anonymous

Interactive database which incorporates a suite of tools designed to aid the interpretation of submicroscopic chromosomal imbalance. Used to enhance clinical diagnosis by retrieving information from bioinformatics resources relevant to the imbalance found in the patient. Contributing to the DECIPHER database is a Consortium, comprising an international community of academic departments of clinical genetics. Each center maintains control of its own patient data (which are password protected within the center''''s own DECIPHER project) until patient consent is given to allow anonymous genomic and phenotypic data to become freely viewable within Ensembl and other genome browsers. Once data are shared, consortium members are able to gain access to the patient report and contact each other to discuss patients of mutual interest, thus facilitating the delineation of new microdeletion and microduplication syndromes.

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• SciCrunch
• 15 years ago - by Anonymous

The American Society for Microbiology is the oldest and largest single life science membership organization in the world. Membership has grown from 59 scientists in 1899 to more than 39,000 members today, with more than one third located outside the United States. The members represent 26 disciplines of microbiological specialization plus a division for microbiology educators. Eligibility for Full Membership is open to any person who is interested in microbiology and holds at least a bachelor''s degree or equivalent experience in microbiology or related field. Many members hold advanced degrees, including a large number at the master''s, PhD, ScD, DrPH and MD level. A regularly matriculated student of microbiology or a related field is eligible to become a student member. There are also separate membership categories for postdoctoral fellows and for transitional scientists in the early years of a career. Microbiologists study microbes--bacteria, viruses, rickettsiae, mycoplasma, fungi, algae and protozoa--some of which cause diseases, but many of which contribute to the balance of nature or are otherwise beneficial. Microbiological research includes infectious diseases, recombinant DNA technology, alternative methods of energy production and waste recycling, new sources of food, new drug development, and the etiology of sexually transmitted diseases, among other areas. Microbiology is also concerned with environmental problems and industrial processes. Microbiology boasts some of the most illustrious names in the annals of science--Pasteur, Koch, Fleming, Leeuwenhoek, Lister, Jenner and Salk--and some of the greatest achievements for mankind. Within the 20th century, a third of all Nobel Prizes in Physiology or Medicine have been bestowed upon microbiologists. The mission of the American Society for Microbiology is to advance the microbiological sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well being worldwide. To achieve these goals, ASM will: * Support programs of education, training and public information; * Publish journals and books; convene meetings, workshops and colloquia; * Promote the contributions and promise of the microbiological sciences; * Recognize achievement and distinction among its practitioners; * Set standards of ethical and professional behavior.

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• SciCrunch
• 15 years ago - by Anonymous

The Database is a research and analysis tool developed at the University of Washington, in the Department of Pharmaceutics. It contains in vitro and in vivo information on drug interactions in humans from the following sources: * 9648 peer-reviewed journal articles referenced in PubMed * 102 New Drug Applications (NDAs) * 411 excerpts of FDA Prescribing Information * In-depth analyses of drug-drug interactions in the context of 40 diseases / co-morbidities. In addition, the database also provides PK Profiles of drugs, QT Prolongation data, including results of TQT studies from recent NDAs, as well as Regulatory Guidances and Editorial Summaries/Syntheses relevant to advances in the field of drug interactions. Access to the Database is licensed by UW Center for Commercialization (C4C) to organizations interested in in-depth information on drug interactions. The Database is particularly useful to scientists/clinicians working in drug discovery and drug development. Database users can search for information using several families of pre-formulated queries based on drug name, enzyme name, transporter name, therapeutic area, and more.

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• SciCrunch
• 15 years ago - by Anonymous

Database of Drosophila genetic and genomic information with information about stock collections and fly genetic tools. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. Additionally, FlyBase accepts data submissions. FlyBase can be searched for genes, alleles, aberrations and other genetic objects, phenotypes, sequences, stocks, images and movies, controlled terms, and Drosophila researchers using the tools available from the "Tools" drop-down menu in the Navigation bar.

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• SciCrunch
• 16 years ago - by Anonymous

Software tool that stores definitions of views of data, along with the ontology concepts they represent. This is a part of the Neuroscience Information Framework (NIF) code stack.

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• SciCrunch
• 13 years ago - by Anonymous

OER serves as a vital interface between the NIH and the biomedical research community by guiding investigators through the process of attaining grants funding and helping them understand and navigate through federal policies and procedures. OER supports extramural research by providing policy and guidance to the 24 NIH Institutes and Centers that award grants. Extramural grants account for approximately 84 percent of NIH''s 29 billion budget. These are awarded to investigators throughout the U.S. and abroad. Approximately 10 percent of the NIH budget supports NIH intramural investigators, NIH staff who conduct research.

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• SciCrunch
• 17 years ago - by Anonymous