Curator Dashboard

This MATLAB toolbox implements a data fitting routine for Neurite Orientation Dispersion and Density Imaging (NODDI). NODDI is a new diffusion MRI technique for imaging brain tissue microstructure. Compared to DTI, it has the advantage of providing measures of tissue microstructure that are much more direct and hence more specific. It achieves this by adopting the model-based strategy which relates the signals from diffusion MRI to geometric models of tissue microstructure. In contrast to typical model-based techniques, NODDI is much more clinically feasible and can be acquired on standard MR scanners with an imaging time comparable to DTI.

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• SciCrunch
• 13 years ago - by Anonymous

Blog by Brian E. Moore, MD, discussing issues pertaining to the practice of neuropathology -- including nervous system tumors, neuroanatomy, neurodegenerative disease, muscle and nerve disorders, ophthalmologic pathology, neuro trivia, neuropathology gossip, job listings and anything else that might be of interest to a blue-collar neuropathologist. Brian E. Moore, MD: Neuropathologist, Memorial Medical Center in Springfield, Illinois. Co-Chair, Southern Illinois University School of Medicine Department of Pathology.

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• SciCrunch
• 15 years ago - by Anonymous

Department of Pharmacology and Toxicology in Brody School of Medicine at East Carolina University prepares students to begin career related to studying biological actions of chemicals. Department offers Ph.D. program and combined M.D./Ph.D. program available through School of Medicine.

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• SciCrunch
• 17 years ago - by Anonymous

Bioinformatics tool used to analyze microarray dose-response data. The analysis provides benchmark dose estimates at which different cellular processes are altered in toxicogenomic experiments.

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• SciCrunch
• 14 years ago - by Anonymous

Software that given a reference sequence, will create a large set of short nucleotide reads, simulating the output from today''s high-throughput DNA sequencers, such as the Illumina Genome Analyzer II.

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• SciCrunch
• 13 years ago - by Anonymous

An interactive analysis program that searches neurophysiological data and plots the results. MatOFF was developed especially for dealing with the complexities common to behavioral neurophysiological experiments. It runs under Windows 2000 or XP and relies on MATLAB version R11.1 (or above) for all operations. MatOFF searches a data file to locate and plot epochs (trials) of special interest to the investigator. Appropriate input data files have time-stamped event codes, usually including neuron action potential firing events (spikes), and digitized analog data. The user specifies a list of event code numbers that uniquely identify a sequence of events. MatOFF uses this sequence to search the raw data file, select the epochs that meet the criteria, time-shift the trials to align them on a common event, order the epochs based on user-selected criteria, and plot the results based on a collection of page formatting specifications. MatOFF will also save extracted data and some statistics to disk. Features: * Powerful, interactive searching tools for locating relevant experimental events * Compatible with Cortex data acquisition program * Compatible with Plexon data acquisition system * Flexible, publication-quality graphical display and printing * Comprehensive scripting language * Supports learning and other dynamic behavior * Integrated interface to MATLAB functions * Automatic alignment of trial data and generation of histograms * Large variety of options for selecting and ordering trial data * Descriptive and non-parametric statistics * XY analog displays * Data export with flexible format control * Up to 72 plots per page * Display templates can be saved and reloaded * Free for public or private use * Adaptable to almost any data file format

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• SciCrunch
• 15 years ago - by Anonymous

A lightweight software pipeline written to process and analyse next-generation sequencing (NGS) data from Illumina, 454, and Ion Torrent platforms. Although originally written for viral data, it is generic enough to work on any NGS dataset. Functions include: duplicate removal, demultiplexing, primer-removal, quality-assurance (QA) graphing, quality control (QC), consensus-generation, minority-variant determination, minority-variant graphing.

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• SciCrunch
• 13 years ago - by Anonymous

Software package that provides the ability to do a number of standard semantic similarity methods and includes novel methods for combining these with dynamic selection of anonymous grouping classes. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible

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• SciCrunch
• 15 years ago - by Anonymous

This project (CheTA) will integrate Cambridge''s chemical text mining tool OSCAR with the U-Compare workflow infrastructure developed by NaCTeM and others. This integration adds chemistry to the world''s largest public collection of interoperable text mining tools and will be highly valued by influential stakeholders both in the JISC community and the wider chemistry community. There is a web interface (beta), http://www.nactem.ac.uk/software/cheta/, or you may download. As part of CheTA, OSCAR has been refactored into different workflows (a sequence of individual components to perform a certain task, in this case named entity recognition of chemical elements).

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• SciCrunch
• 16 years ago - by Anonymous

Information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) providing information about certain hematologic diseases in easy-to-understand language: online, in booklets and fact sheets, by email, and over the phone to patients, health professionals and the public. The NHDIS provides the following informational products and services: * Response to inquiries about hematologic diseases, ranging from information about available patient and professional education materials to referrals to patient support organizations. Assistance is available by phone (8:30 a.m. to 5 p.m. eastern time, M-F), fax, mail, and email. * Publications about hematologic diseases, provided free of copyright, in varying reading levels. Available online or in hard copy. NHDIS also sends publications to health fairs and community events. * Referrals to health professionals through the National Library of Medicine''''s MEDLINEplus, which includes a consumer-friendly listing of organizations to assist in the search for physicians and other health professionals.

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• dkNET
• 14 years ago - by Anonymous

Public university located in Rostock, Mecklenburg-Vorpommern, Germany. Founded in 1419.

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• SciCrunch
• 13 years ago - submitted by Andrea Stagg

A software suite using feature-based classifiers for somatic mutation prediction from paired tumour/normal next-generation sequencing data. mutationSeq has the advantages of integrating different features (e.g., base qualities, mapping qualities, strand bias, and tailed distance features), and validated somatic mutations to make predictions. Given paired normal/tumour bam files, mutationSeq will output the probability of each candidate site being somatic.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool for the taxonomic assignment of Next Generation Sequencing reads using multiple reference taxonomy.

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• SciCrunch
• 12 years ago - by Anonymous

Software package for input, quality assessment and exploration of high-throughput sequence data. Used for input, quality assurance, and basic manipulation of `short read'' DNA sequences such as those produced by Solexa, 454, and related technologies, including exible import of common short read data formats.

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• SciCrunch
• 13 years ago - by Anonymous

The mission of the Thompson Center is to improve the lives of individuals and families affected by autism and neurodevelopmental disorders through world class programs that integrate research, clinical service delivery, education and public policy. The Thompson Center''s vision is to become a recognized national center of excellence that serves as a model of interdisciplinary practice, research and training in the field of autism and neurodevelopmental disorders. At the MU Thompson Center, education and training activities are a key part of our mission. Our goal is to teach others about the needs of persons with autism and other neurodevelopmental disorders and their families. In addition, we strive to help learners acquire skills needed to improve the outcomes of individuals with developmental differences. These skills include evidence-based assessment and intervention strategies, interdisciplinary approaches to service delivery, research methods, and policy development. The Thompson Center offers a range of health, educational and behavioral services in one location for individuals with autism and other developmental concerns. Professionals from different disciplines strive to deliver family-centered care that is comprehensive and coordinated. Autism recently has been recognized as a national public health concern, and federal research funding in this area has increased substantially. Faculty members engage in research that will lead to early identification, treatment and ultimately prevention of autism spectrum disorders (ASD). How findings may eventually translate into improved outcomes in clinical and community settings is a primary goal of our research.

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• SciCrunch
• 15 years ago - by Anonymous

A structured controlled vocabulary of the development of Caenorhabditis elegans.

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• SciCrunch
• 13 years ago - by Anonymous

A statistical software package for identifying protein-associated transcripts from RIP-seq experiments. Infer and discriminate RIP peaks from RIP-seq alignments using two-state HMM with negative binomial emission probability. While RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides a suite of bioinformatics tools integrated within this self-contained software package comprehensively addressing issues ranging from post-alignments processing to visualization and annotation.

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• SciCrunch
• 13 years ago - by Anonymous

Web server for functional enrichment analysis and conversions of gene lists. Web based tool for functional profiling of gene lists from large scale experiments. Has web interface with powerful visualization. Used for analyzing data from any organism.

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• SciCrunch
• 17 years ago - by Anonymous

An application ontology for the domain of Sleep Medicine.

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• SciCrunch
• 13 years ago - by Anonymous

AEO represents the Adverse Event Ontology, a community-driven ontology developed to standardize and integrate data on biomedical adverse events (e.g., vaccine adverse events) and support computer-assisted reasoning. The AEO also can be found in BioPortal, http://bioportal.bioontology.org/ontologies/45534?p=terms

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• SciCrunch
• 16 years ago - by Anonymous