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Collects and stores genetic (DNA) samples along with associated healthcare information from patients of Northwestern-affiliated hospitals and clinics. This resource is available to scientists to conduct groundbreaking genetic research. The information and blood samples provided will be used by researchers to examine the role genes play in the development and treatment of common diseases. The NUgene Project seeks to increase the understanding of genetic mechanisms underlying common diseases, assist in the development of DNA-based technology for diagnosis and treatment of disease, and aid physicians and other healthcare providers in the application of genetics to the practice of medicine. NUgene participants are recruited throughout the Northwestern-affiliated healthcare community in order to create an ethnically and medically diverse population for research. Participants must be 18 years of age or older and receive their medical care from a Northwestern-affiliated provider, regardless of health status. Consenting individuals complete all aspects of enrollment in a single meeting with a research coordinator. The enrollment process includes the donation of a single sample of blood and the completion of a self-administered questionnaire. Participants also sign a consent form during this encounter. The NUgene Project is an interdisciplinary project that relies on the expertise of individuals working in a variety of fields, including science, medicine, clinical research, statistics, epidemiology, and computational biology. NUgene''s multidisciplinary approach has spurred collaborations within Northwestern-affiliated institutions and with other outside institutions. This collaboration of ideas is the future of genetics and genomic research., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 17 years ago - by Anonymous

A database of domain-domain and peptide-mediated interactions of known 3D structures. The database of 3D Interaction Domains (3did) is a collection of domain-domain and domain-peptide interactions for which high-resolution three-dimensional structures are known. 3did exploits structural information to provide critical molecular details necessary for understanding how these interactions occur. It also offers an overview of how similar in structure are interactions between different members of the same protein family. The database also contains GO-based functional annotations and interactions between yeast proteins from large-scale interaction discovery studies. Sponsors: This resource is partially supported by the Spanish Ministerio de Educacin y Ciencia (PSE-010000-2007-1 and BIO2007-62426) and the 3D-Repertoire from the European Commission under FP6 contract LSHG-CT-2005-512028. Keywords: Database, Domain, Peptide, Protein, 3D structure, Interaction, Dimentional, Structure, Molecular, Functional, Annotation, Interaction, Yeast, Study, Research,

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• SciCrunch
• 17 years ago - by Anonymous

Web tool for translating neurodevelopemental time across species and predicting neurodevelopemental events. This tool was created because clinicians and researchers rely on neurodevelopment data obtained from a variety of non-human species, it is essential to be able to relate studies across the different experimental animals, and ultimately to humans, in an easily accessible format. This web site is based on a mathematical model originally described by Finlay and Darlington (Science, 268:1578-84) that predicts post conception (PC) dates using log transformations. It integrates hundreds of empirically-derived neural events to translate neurodevelopmental time across hamsters, mice, rats, rabbits, spiny mice, guinea pigs, ferrets, cats, rhesus monkeys and humans.

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• SciCrunch
• 17 years ago - by Anonymous

Public research university located in the medieval city of Regensburg, Bavaria, a city that is listed as a UNESCO World Heritage Site.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

A computer-readable format for representing models of biochemical reaction networks in software. It''s applicable to models of metabolism, cell-signaling, and many others. This website is the portal for the global SBML development effort; you can find information about all aspects of SBML.

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• SciCrunch
• 14 years ago - by Anonymous

V-Cell is a remote user modeling and simulation environment utilizing Java''s Remote Method Invocation (RMI). The biologically oriented user interface allows experimentalists to create models, define cellular geometry, specify simulations and analyze the simulation results. The results are run and stored on a remote server and can be reviewed in the software and/or exported in a variety of popular formats. The design of the biological to mathematical mapping allows for separate use of biological and math components, and includes automatic mathematical simplification using pseudo-steady approximations and mass conservation relationships. This allows for direct specification of mathematical problems, performing simulations and analysis on those systems. The stand alone mathematics user interface is also a powerful tool for modeling reaction-diffusion systems. A transparent general purpose solver is used to translate the initial biological description into a set of concise mathematical problems. The solver is transparent to the average user, but is accessible to the theorist as the Math Editor component. The software is composed of three main components: 1. The modeling framework represents the physiological models of the Virtual Cell and allows for persistence and database support. 2. The mathematics framework transparently solves an important class of mathematical problems encountered in the cellular modeling. 3. The WWW accessible graphical user interface provides access to the technology mentioned above. The user interface has been developed using Java 2 Applets.

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• SciCrunch
• 17 years ago - by Anonymous

Software application that is a stepwise approach to identifying recombination breakpoints in a sequence alignment (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous

The GPCRDB is a molecular-class information system that collects, combines, validates and stores large amounts of heterogenous data on G protein-coupled receptors (GPCRs). :The GPCRDB contains data on sequences, ligand binding constants and mutations. In addition, t he system provides computationally derived data such as multiple sequence alignments, homology models, and a series of query and visualization tools. :The GPCRDB is designed to be a data storage medium, as well as a tool to aid biomedical scientists with answering questions by offering a single point of access to many types of data that are integrated and visualized in a user-friendly way. Although most parts of the GPCRDB are self-explanatory, if you have not used this resource before it is adviced that you to take a look at the usage page. Sponsors: This resource is supported by Organon and Unilever, and the NIH. Keywords: G protein, Coupled, receptor, Molecular, Heterogenous, Data, Sequence, Ligand, Mutation, Computational, Software, Alignment, Homology, Model, Visualization, Tool, Biomedical, Scientist, Integration,

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• SciCrunch
• 17 years ago - by Anonymous

Platform for exploring spinal cord at cellular and molecular levels. Map of gene expression for adult and juvenile mouse spinal cord. Provides map of normal mouse when used to compare gene expression in diseased or injury models. Interactive database of gene expression mapped across all anatomic segments of mouse spinal cord at postnatal days 4 and 56. Indexed set of images based on RNA in situ hybridization data, searchable and sortable by gene, age, expression, cervical, thoracic, lumbar, sacral, and coccygeal segments.

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• SciCrunch
• 17 years ago - by Anonymous

The National Eye Institute Research funding resource provides notifications of funding opportunities in eye and vision research. National Eye Institute supports the 28 grant mechanisms listed on the site and lists extramural funding data. The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. NEI research leads to sight-saving treatments reduces visual impairment and blindness and improves the quality of life for people of all ages. NEI-supported research has advanced our knowledge of how the visual system functions in health and disease. Vision research is supported by the NEI through approximately 1600 research grants and training awards made to scientists at more than 250 medical centers hospitals universities and other institutions across the country and around the world. The NEI also conducts laboratory and patient-oriented research at its own facilities located on the NIH campus in Bethesda Maryland.

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• SciCrunch
• 17 years ago - by Anonymous

Multi modal atlas of human brain that integrates anatomic and genomic information, coupled with suite of visualization and mining tools to create open public resource for brain researchers and other scientists. Data include magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), histology and gene expression data derived from both microarray and in situ hybridization (ISH) approaches. Brain Explorer 2 is desktop software application for viewing human brain anatomy and gene expression data in 3D.

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• SciCrunch
• 16 years ago - by Anonymous

It is at the forefront of new ideas and developments in microscopy and imaging. The RMS is the only truly international microscopical society, drawing distinguished members from all over the world. It also serves the needs of its company members who represent all the major manufacturers and suppliers of microscopes, equipment and services. In addition to this, the Society is pursuing an initiative to encourage young microscope users who may go on to influence microscopy in years to come. The Society is dedicated to advancing science, developing careers and supporting wider understanding of science and microscopy through its Science and Society activities. In support of the above, it publishes The Journal of Microscopy and microscopy handbooks, as well as helping young scientists through bursaries. The Society is incorporated by Royal Charter. Its governing documents are its Charter and By-laws. The most recent AGM minutes, Trustees Report and Accounts are available below - 2007 AGM draft minutes Full 2007 Trustees Report and Accounts - as submitted to the Charity Commission The RMS is a member of: - the Foundation for Science and Technology - the Biosciences Federation - the International Federation of Societies for Microscopy - the European Microscopy Society training opportunities; jobs.

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• SciCrunch
• 14 years ago - by Anonymous

Software application (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous

The Bernstein Network for Computational Neuroscience, Germany, is a funding initiative of the German Federal Ministry of Education and Research that supports the development of this field in Germany. Understanding the brain is the prerequisite for creating new methods for prevention and treatment of diseases of the nervous system. It may also help developing new strategies for learning and teaching. It may even be used for the design of new, ''intelligent'' technical devices, such as neuroprostheses or more powerful computer systems. For investigating the brain, the interdisciplinary approach of computational neuroscience, in which experts in biology, physics, psychology, medicine, mathematics and engineering join forces, holds especially promising perspectives. By combining experiment, data analysis, theoretical modelling and computer simulations, computational neuroscience allows translating basic research to targeted applications. The Bernstein Network currently comprises more than 200 research groups at over 20 locations all over Germany. It entertains partnerships with more than 20 companies. Besides its research activities, the network offers attractive teaching and training options for young researchers. A large number of open positions are available, ranging from PhD students positions up to professorships. Keywords: grant, funding, resource, training, job, research, Network, Scientist, Teaching, biology, physics, psychology, medicine, mathematics, engineering, Computational, Neuroscience, Computational Neuroscience, Germany,

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• SciCrunch
• 17 years ago - by Anonymous

Data sets, tools and computational techniques for modeling of protein interactions, including docking benchmarks, docking decoys and docking templates. Adequate computational techniques for modeling of protein interactions are important because of the growing number of known protein 3D structures, particularly in the context of structural genomics. The first release of the DOCKGROUND resource (Douguet et al., Bioinformatics 2006; 22:2612-2618) implemented a comprehensive database of cocrystallized (bound) protein-protein complexes in a relational database of annotated structures. Additional releases added features to the set of bound structures, such as regularly updated downloadable datasets: automatically generated nonredundant set, built according to most common criteria, and a manually curated set that includes only biological nonobligate complexes along with a number of additional useful characteristics. Also included are unbound (experimental and simulated) protein-protein complexes. Complexes from the bound dataset are used to identify crystallized unbound analogs. If such analogs do not exist, the unbound structures are simulated by rotamer library optimization. Thus, the database contains comprehensive sets of complexes suitable for large scale benchmarking of docking algorithms. Advanced methodologies for simulating unbound conformations are being explored for the next release. The Dockground project is developed by the Vakser lab at the Center for Bioinformatics at the University of Kansas. Parts of Dockground were co-developed by Dominique Douguet from the Center of Structural Biochemistry (INSERM U554 - CNRS UMR5048), Montpellier, France.

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• SciCrunch
• 17 years ago - by Anonymous

IDARS is an international scientific organization that promotes and fosters the research and collaboration of scientists around the world in the area of substances of abuse and addiction. Our focus is to foster research in molecular, cellular and systems biology and includes neuropharmacological, neurobehavioral, neurochemical and neuroanatomical themes. The purposes of IDARS are scientific, educational and charitable. We strive to promote excellence in: advancing the understanding of drug abuse, substance abuse and addictions, including the part they play in behaviors of humans and in animal models bringing together scientists of varying backgrounds and disciplines within the field of drug abuse research integrating drug abuse research directed at all levels of biological organization and its translation to improvement in clinical prevention and treatment efforts promoting education in the addiction sciences informing the general public on the results and implications of current research in the addiction sciences promoting other activities that will contribute to the development of addiction sciences IDARS is a 501c3 nonprofit organization.

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• SciCrunch
• 17 years ago - by Anonymous

The English web portal www.research-in-germany.de is an information platform and contact point for all looking to find out more about Germany''s research landscape and its latest research achievements. An interdisciplinary portal The portal not only informs researchers and scientists about what Germany has to offer them. It also covers the 17 future fields of the High-Tech Strategy and other fields of science and learning. In addition, it addresses a whole host of other players from politics and government, business and industry, or science and research, as well as our young researchers, of course. Editorial responsibility for the portal lies with the German Academic Exchange Service (DAAD), acting on behalf of the Federal Ministry of Education and Research (BMBF). The Research in Germany Land of Ideas Campaign The campaign to Promote Innovation and Research in Germany was launched in November 2006 to position German research in the international market. Since then, the campaign has been running worldwide under the brand Research in Germany Land of Ideas. Its declared goal is to highlight research in Germany and the advantages that it offers. This makes German research institutions more visible to our partners, customers and competitors. The campaign primarily aims to strengthen the networks that exist between German research institutions and our strategic partners worldwide. A further goal involves inspiring the world''s best minds in research and development to come to Germany to carry out their projects and then to make the most of the resulting opportunities that open up for both sides. Not to forget the goal of encouraging more international cooperation in science and research. job resource; funding resource; grants; training resource.

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• SciCrunch
• 17 years ago - by Anonymous

CORE MISSION: The core mission of the IRSF is to fund research for treatments and a cure for Rett syndrome while enhancing the overall quality of life for those living with Rett syndrome by providing information, programs, and services. ELEMENTS OF MISSION RESEARCH: The IRSF will coordinate, cultivate, accelerate, and fund research that will produce a cure for Rett syndrome and reveal and develop treatments that will make the lives of people living with Rett syndrome richer and free of pain and discomfort. FAMILY SUPPORT: The IRSF will assist families of individuals living with Rett syndrome by providing them with connections to critical and useful information, programs, services, and support from diagnosis to day-to-day life. ADVOCACY AND AWARENESS: The IRSF will advocate for and raise awareness about individuals with Rett syndrome so the scientific and medical community, policy makers, educators, care givers, and the general public can more thoroughly know, understand, and be motivated to help the research efforts and individuals dealing with Rett syndrome on a daily basis. ACCOMPLISHING THE MISSION FUND DEVELOPMENT: To accomplish this core mission, the core priority of the IRSFs leadership will be effective, assertive, comprehensive, and strategic fundraising. FISCAL RESPONSIBILITY: The IRSF will operate in accordance with those generally accepted principles necessary to maintain a Four Star Charity Navigator rating. Keywords: grants, funding, research, advocacy, awareness, family support, education, fundraising,

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• SciCrunch
• 17 years ago - by Anonymous

Group provides systematic and comprehensive study of sensory motor behavior that combines movements of eyes, head, arm and hand. Study of sensory motor coordination also include design of rigorous behavioral paradigms to detect and monitor treatment of diseases or injuries affecting sensory motor function. Other investigations include development of novel strategies that either promote recovery from injury or protect neurons from disease or injury.

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• SciCrunch
• 16 years ago - by Anonymous

School of Pharmacy offers two graduate Doctor of Philosophy degree programs. Health Services and Outcomes Research program emphasizes research related to access, cost, quality and outcomes of pharmaceuticals and health services. Pharmaceutical and Pharmacological Sciences program emphasizes basic laboratory research and training in biomedical sciences.Graduate programs feature multidisciplinary coursework and seminars to provide students with diversified background in theories and techniques of contemporary research.

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• SciCrunch
• 17 years ago - by Anonymous