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Interdisciplinary unit organized under University of Michigan's Medical School - Department of Radiology, dedicated to supporting research on structures and functions of brain that underlie cognitive and affective processes, and research on functional MRI and associated research tools. Provides equipped physical facility and intellectual support services for investigators.
EMAL is part of University of Michigan’s School of Earth and Environmental Sciences. Houses CAMECA SX100 electron microprobes, Rigaku X-ray diffractometers, and JEOL JSM-7800FLV field-emission scanning electron microscope. These instruments are used by researchers for chemical and structural characterization of solid materials.
Performs scanning on per-request basis; maintains secure database of scanned images and associated metadata; instructs and provides technical support to faculty and staff for DP use; supports of live-view microscopy for frozen sections and testing and validation of new whole-slide imaging solutions.
Molecular Biology Core (MBC) is School of Dentistry core and provides real-time quantitative PCR service (ABI ViiA7, ABI-7500 instruments), methodology, technique and experiment design consultation, analytical software training, data analysis, statistics and result interpretation assistance
Core offers services and instruments. Offers Scanco μCT 100 micro-computed tomography system which provides high resolution scans of radio opaque specimens such as bone, contrasted soft tissue, bio materials, etc.
Histology core facility at the University of Michigan School of Dentistry provides histological services using standard histological techniques. The core specializes in sectioning of hard (demineralized) tissues.
CyTOF Core shares equipment and expertise with researchers. Provided instruments include: Helios CyTOF System (Suspension CyTOF), Hyperion CyTOF System (Imaging CyTOF), Attune Flow Cytometer, ÄKTA Pure FPLC, NanoDrop 2000c Spectrophotometer. Offered services include Human immune profiling panel for 29-color analysis of cells in suspension; Mouse immune profiling panel for 16-color analysis of cells in suspension; Custom CyTOF antibody conjugation; Data acquisition of cells in suspension using Helios CyTOF; Image acquisition of tissue sections using Hyperion CyTOF.
Areas of Expertise:CSCAR staff have expertise in the areas of Biostatistical analyses; Formulation of research aims and development of plans for data collection and analysis; expertise in R, Python, SAS, SPSS, Stata, and Fortran. In addition, can advise clients on the use of number of other statistical and technical software packages.
Core provides services in Clinical Chemistry, Clinical Mass Spectrometry , Hematology, Body Fluids, Urinalysis, Quantitative Flow Cytometry, Coagulation, BioChemical Genetics.
Core provides services for X-Ray and microporous materials characterization.
Core offers mass spectrometry services. Provided instruments include
Software repository for cell segmentation benchmark.
Software R package to quickly find motif matches for many motifs and many sequences. Wraps C++ code from the MOODS motif calling library.
Software R package for detection of differentially bound regions in ChIP-seq data with sliding windows, with methods for normalization and proper FDR control.
Software tool that enables the automatic evaluation of muscle tissue on elastography imaging using MATLAB.
Data analysis platform, enables scientists without coding or bioinformatics expertise to access and run the end-to-end data analysis workflow. The platform includes the Pipeline module which processes FASTQ files and the Insights module for downstream analysis.
Fully-staffed, open access, analytical research facilities at Penn State's Institute of Energy and the Environment. Provided services include radiocarbon measurements on carbon-bearing materials using an Accelerator Mass Spectrometer; high-resolution 3D micro/nano computed tomography of biological and synthetic materials; analysis of environmental and biological samples for emerging and legacy contaminants using high resolution mass spectrometry including (Triple Quad GC-MS/MS, Triple Quad LC-MS/MS, Pyrolysis GC-MS, QExactive LC-MS, Combustion Ion Chromatography, DART-MS with Ion Rocket) and a Laser Direct Infrared Chemical Imaging System. Sample Preparation and Analysis. Provides training for researchers and equipment users, method development, data analysis.
Laboratory is equipped with sample preparation and analysis equipment that support established analytical procedures including:Organic fluorine compounds-PFAS screening: EPA 1621; PFAS targeted and non-targeted analysis: EPA 537.1, EPA 1633; Pharmaceuticals and personal care products: EPA 1694; Agricultural chemicals: pesticides, herbicides-targeted and non-targeted analysis: various methods GC-MS/MS and LC-MS/MS; Volatile organic compounds: EPA 8260D (SW-846); Semivolatile organic compounds: EPA 8270E (SW-846); Dioxins and furans: EPA 23; Total petroleum hydrocarbons: EPA 8440; Microplastics and nanoplastics.
Vevo LAB offers basic and advanced tools for visualizing, quantifying and characterizing disease progression from ultrasound images obtained on a Vevo system
Software tool to predict Hi-C matrices based on ChIP-Seq data from histones using cGAN approach.