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The Lausanne Genomics Technologies Facility (GTF) is a genomic technologies core laboratory serving the Lausanne and Lemanic region research community. It is housed in and administered by the Center for Integrative Genomics. The GTF offers a range of microarrays services, including : providing access to the instrumentation and the consumables that are required for the use of the pre-printed oligonucleotide microarrays available from Affymetrix and Illumina as well as miRNA gene microarrays from Agilent Technologies providing access to and supporting applications using the Illumina Genome Analyzer 2 ultra high throughput DNA sequencing platform providing access to the instrumentation and the consumables that are required for performing quantitative real-time PCR analyses using the Applied Biosystems 7900HT Sequence Detection System. providing bioinformatics support and consultation services at the stages of experimental design, data collection and storage, image analysis and data analysis acting as a center of experience, expertise and training in microarray and quantitative PCR technologies and methodologies. Laboratory space and computer workstations are available to users wanting to perform the experiments and/or analyses in the facility. The GTF also acts as an information clearing house for the user community by providing a forum for the sharing of methods, protocols and experience generated by the GTF and community scientists using microarray and quantitative PCR technology investigating and implementing, when appropriate, microarray-based methods for applications other than gene expression monitoring (e.g. SNP detection) participating in the evaluation of new RNA expression profiling and nucleic hybridization detection technologies as they develop and incorporate the appropriate technologies into the services offered by the facility

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• 17 years ago - by Anonymous

Cytopathology Foundation is a non-profit organization dedicated to the health care for the advancement of art and science of Cytopathology dealing with study of cells for proper disease management especially cancer. Cytopathology is a well established diagnostic sub-specialty of pathology. Instead of using surgically removed tissue to arrive at a diagnosis it attempts to identify diagnostic and prognostic information from dispersed cells obtained by non-invasive or minimally invasive techniques. An example, and its greatest success story thus far, is the role it has played in the battle with cervical cancer. The introduction of the Pap smear has contributed immensely to the early diagnosis and significantly decreased mortality of cervical cancer. Activities of the foundation 1. Support the mission statement in general. 2. Support the editorial and publication expenses of CytoJournal. 3. Future activities may include publication and marketing of cytopathology related literature, to generate funds. 4. Support any other scholarly activities in Cytopathology and related areas.

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• 17 years ago - by Anonymous

Cython is a language that makes writing C extensions for the Python language as easy as Python itself. Cython is based on the well-known Pyrex, but supports more cutting edge functionality and optimizations. The Cython language is very close to the Python language, but Cython additionally supports calling C functions and declaring C types on variables and class attributes. This allows the compiler to generate very efficient C code from Cython code. This makes Cython the ideal language for wrapping external C libraries, and for fast C modules that speed up the execution of Python code. Sponsor. Google and Enthought funded Dag Seljebotn to greatly improve Cython integration with NumPy. Kurt Smith and Danilo Freitas were funded through the Google Summer of Code program to work on improved Fortran and C support respectively.

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• 17 years ago - by Anonymous

An efficient methodology for detecting and delineating gains and losses of chromosomal material in DNA copy-number data.

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• 13 years ago - by Anonymous

The Cystic Fibrosis Foundation has built a dynamic pipeline for the development of more new potential cystic fibrosis (CF) therapies than ever before. To treat a complex disease like CF, therapies must target problems in the airways and the digestive system. In the CF drug development pipeline, there also are promising new therapies designed to rectify the cause of CF a faulty gene and/or its faulty protein product. Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that: clogs the lungs and leads to life-threatening lung infections; and obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food. In the 1950s, few children with cystic fibrosis lived to attend elementary school. Today, advances in research and medical treatments have further enhanced and extended life for children and adults with CF. Many people with the disease can now expect to live into their 30s, 40s and beyond.

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• 17 years ago - by Anonymous

In probability theory and statistics, the cumulative distribution function (CDF), or just distribution function, describes the probability that a real-valued random variable X with a given probability distribution will be found at a value less than x. Intuitively, it is the area so far function of the probability distribution. Cumulative distribution functions are also used to specify the distribution of multivariate

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• 17 years ago - by Anonymous

Cryptococcus neoformans is an encapsulated yeast that infects the human host via the respiratory tract where it usually causes an inapparent infection. In the susceptible host, it may disseminate, typically producing a chronic and life-threatening meningitis. The Cryptococcus neoformans serotypes A and D are responsible for the overwhelming majority of pulmonary infections in AIDS patients. Cryptococcus neoformans strain H99 Latest Data Release - May 19, 2004 To date, we have isolated ca. 3750 cDNA clones from Cryptococcus neoformans strain H99 in collaboration with Drs. Juneann Murphy and Dave Dyer at the University of Oklahoma Health Sciences Center''s Department of Microbiology and Immunology in Oklahoma City and Kent Buchanan at the Tulane University Medical School, New Orleans, LA. The Cryptococcus neoformans strain H99 EST''s have been generated by Doris Kupfer, Heather Bell, Sunkyoung So, Yuong Tang, and Jennifer Lewis at the University of Oklahoma''s Advanced Center for Genome Technology, in the Department of Chemistry and Biochemistry. We now have end sequenced all available templates (ca. 7500 reactions) from both ends of the directionally cloned inserts after excision into pBlueScript SK-. . All of our data is available from our ftp site, and we now have added the ability to perform blast searches on this data. A keyword search of a blastx search of GenBank with this data also is available but we have not yet linked this to a unigene database as the number of EST''s sequenced doesn''t warrent this yet.

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• 17 years ago - by Anonymous

This Blast server offers searches against all D. rerio finished and unfinished clones in the Sanger sequencing pipeline. You can now also search the de novo assemblies generated from sequencing of one doubled haploid homozygous individual of each the AB and Tuebingen strain. Both fish were sequenced to ~40x coverage using Illumina GA sequencing technology and the sequences were assembled using Phusion2, resulting in a 1,33 Gb AB and a 1.48 Gb Tuebingen assembly. Due to the short reads and short inserts and no integration of physical or genetic map data, both assemblies are highly fragmented - with an N50 contig size of about 5kb. Mis-assembly errors may also be present in the contigs. Please note these assemblies are independent additions to the assemblies released by the zebrafish genome project and are intended to aid identification of polymorphisms between these two strains. Charity. Genome Research Limited is a charity registered in England with number 1021457

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• 17 years ago - by Anonymous

Criterion Ventures is launching a new venture that will adapt existing financial services and connect them with consumers through affinity groups to address the needs of the cash market of healthcare. Currently, the healthcare industry is dominated by an insurance market. But sitting next to the insurance market is a $300 billion/year cash market for health care. This cash market lacks the rational pricing, products, services and intermediaries needed to deliver health care affordably and in a way that maximizes access. In the end, consumers are not getting the best value per dollar spent. By introducing and bringing to scale innovative products and services, and connecting them to consumers through existing affinity groups whose members are struggling with the impact of the cash portion of healthcare, we will be able to rationalize the market. By creating a rational market we will bring greater value to consumers for their healthcare dollars and increase access to care. The business will draw revenues from four sources: Charging transaction fees to consumers who use our products Charging interest to consumers who take advantage of our lines of credit offerings Interest earned on deposits that we or our partners will hold for consumers Charging management fees to affinity groups for setting up their customized set of products and services. Partners. Thomas H. Cochran, Managing Director, CivilCredit Advisors Catherine (Cathy) Dunham, Director, Access Project Richard Eskow, CEO, Health Knowledge Systems Tim Freundlich, Founder and Managing Principal, Good Capital; Director of Strategic Initiatives, Calvert Foundation Ben Geyerhahn, Principal, Hudson TG Kevin Jones, Founding Principal, Good Capital Claudia Machaver, Consultant Robert Mittman, Founder, Facilitation, Foresight, Strategy Sara Olsen, Founding Partner, SVT Group Mark Rukavina, Executive Director, Access Project Michael Tobman, Principal, Hudson TG Dana Wright, Founder, Take Action, Inc.

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• 17 years ago - by Anonymous

The annual Cosyne meeting provides an inclusive forum for the exchange of experimental and theoretical/computational approaches to problems in systems neuroscience. The first Cosyne meeting, held in 2004 at Cold Spring Harbor Laboratory, drew over 350 participants. Since 2005, the meeting has been held in Salt Lake City, Utah. It has attracted a growing number of participants, from nearly 400 in 2005 to over 500 in 2010. To encourage interdisciplinary interactions, the main meeting is arranged in a single track. A set of invited talks are selected by the Executive Committee, and additional talks and posters are selected by the Program Committee, based on submitted abstracts. Cosyne topics include but are not limited to: neural coding, natural scene statistics, dendritic computation, neural basis of persistent activity, nonlinear receptive field mapping, representations of time and sequence, reward systems, decision-making, synaptic plasticity, map formation and plasticity, population coding, attention, computation with spiking networks. Sponsor. Thanks to the generosity of The Gatsby Charitable Foundation, of Qualcomm Incorporated and of Brain Corporation, up to 40 travel grants will be available to support student and postdoc participation in the main Cosyne meeting.

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• 17 years ago - by Anonymous

DNA Direct was founded in 2005 to address the growing need for genetic expertise and guidance across the healthcare continuum. Genetic technology is rapidly advancing and new associations between common genes and disease are being discovered every day. With more than 2000 molecular diagnostic and genetic tests available today, the impact of genetics has never been greater and is becoming an integral part of medicine and patient care To bring the power of personalized medicine to patients, providers and payors reducing health risks, preventing disease, and better targeting therapies. DNA Direct''s Precision Health Services include: * Utilization Management * Clinical Decision Support Programs * Clinical Management * Online and Telephone Support Resources for Providers and Patients * Lab Network

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• 17 years ago - by Anonymous

PPD is a leading global contract research organization (CRO), celebrating 25 years of providing drug discovery, development and lifecycle management services. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. With offices in 41 countries and more than 10,500 professionals worldwide, PPD applies innovative technologies, therapeutic expertise and a commitment to quality to help clients and partners accelerate the delivery of safe and effective therapeutics and maximize the returns on their R&D investments. Discovery Services: BioDuro, A PPD Company A drug discovery services company focused on integrated drug discovery programs Nonclinical development Preclinical services partners. Compound Partnering PPD''s compound partnering business is now Furiex Pharmaceuticals, Inc., an independent, publicly traded company. Collaboration with Merck Our strategic collaboration with Merck enabled us to acquire its vaccines and biologics infrastructure, broaden our therapeutic expertise and expand our existing relationship. Alliance with WHISCON We have expanded our post-approval safety expertise and risk management through an alliance with World Health Information Science Consultants. Partnership with PUL To meet growing client demand in Southeast Asia, we partnered with Peking Union Lawke Biomedical Development Limited (PUL) to establish our central lab services in China. Our e-Newsletter is your source for what is happening at PPD and in the CRO industry.

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• 17 years ago - by Anonymous

Software program for estimating frequencies of haplotypes of large numbers of diallelic markers from unphased genotype data from unrelated subjects (entry from Genetic Analysis Software)

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• 14 years ago - by Anonymous

Continua Health Alliance is a non-profit, open industry coalition of the finest healthcare and technology companies joining together in collaboration to improve the quality of personal healthcare. With more than 200 member companies around the world, Continua is dedicated to establishing a system of interoperable personal health solutions with the knowledge that extending those solutions into the home fosters independence, empowers individuals and provides the opportunity for truly personalized health and wellness management. Mission To establish a system of interoperable personal telehealth solutions that fosters independence and empowers people and organizations to better manage health and wellness Objectives The Continua Health Alliance is comprised of technology, medical device and health care industry leaders dedicated to making personal telehealth a reality. Our objectives include: Developing design guidelines that will enable vendors to build interoperable sensors, home networks, telehealth platforms, and health and wellness services. Establishing a product certification program with a consumer-recognizable logo signifying the promise of interoperability across certified products. Collaborating with government regulatory agencies to provide methods for safe and effective management of diverse vendor solutions. Working with leaders in the health care industries to develop new ways to address the costs of providing personal telehealth systems.

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• 17 years ago - by Anonymous

Consumers Union (CU) is an expert, independent, nonprofit organization whose mission is to work for a fair, just, and safe marketplace for all consumers and to empower consumers to protect themselves. The organization was founded in 1936 when advertising first flooded the mass media. Consumers lacked a reliable source of information they could depend on to help them distinguish hype from fact and good products from bad ones. Since then CU has filled that vacuum with a broad range of consumer information. To maintain its independence and impartiality, CU accepts no outside advertising and no free samples and employs several hundred mystery shoppers and technical experts to buy and test the products it evaluates. The organization generates more than $200 million in revenue, and a staff totaling more than 600 work at CU''s 50 state-of-the-art labs and offices in Yonkers, N.Y.; its 327-acre Auto Test Center in East Haddam, Conn.; and our three advocacy offices, in Washington, D.C., Austin, Texas, and San Francisco. Consumers Union is governed by a board of 18 directors who are elected by CU members and meet three times a year

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• 17 years ago - by Anonymous

C-Maps project is an international collaboration between Discovery Informatics and Computing Laboratory in Indiana University Purdue University Indianapolis (IUPUI) and State Key Laboratory of Intelligent Technology and Systems (LITS) in Tsinghua University China. Connectivity Maps (C-Maps) is created to connect diseases with genes/proteins whose mutations cause them and drugs which treat them. Recent studies focus on developing systematic methods to build C-Maps using gene-expression data to connect small molecules, genes, and disease. Justin Lamb et. al. established a systematic approach to build C-Map using gene-expression profiling as the common vocabulary to connect small molecules, genes, and diseases. They created the first installment of a reference collection of gene-expression profiles from cultured human cell treated with bioactive small molecules, together with pattern-matching software to mine these data [1]. Atul J Butte et. al build a C-Maps using the UMLS (Unified Medical Language System) annotation of gene expression data to connect phenotypic, disease, environmental and experimental contexts as well as genes with differential expression associated with these concepts [2] Sponsor. We would like to thank the generous grant support from Indiana University - Purdue University Indianapolis, and National Basic Research Program of China (973 Program), National High Technology Research and Development Program of China (863 Program).

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• 17 years ago - by Anonymous

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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• 17 years ago - by Anonymous

It is a specialized research center supported by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). PSI is a federal, university, and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure. The long-range goal of PSI is to solve 10,000 protein structures in 10 years and to make the three-dimensional atomic-level structures of most proteins easily obtainable from knowledge of their corresponding DNA sequences. CESG is located within the Department of Biochemistry at the University of Wisconsin-Madison (Madison, WI) and the Department of Biochemistry at the Medical College of Wisconsin (Milwaukee, WI). CESG develops new methods and technologies to address unique eukaryotic bottlenecks and disseminates its methodologies and experimental results to the scientific community worldwide through: :- Cell-Free Protein Production Workshops :- Plasmids at PSI Materials Repository :- Posters Presented at Scientific Meetings :- Publications in PubMed / PubMed Central :- Sesame (LIMS) Available for Researchers :- Solved Structures in the Protein Data Bank :- Technology Dissemination Reports They have welcomed requests by researchers to solve eukaryotic protein structures, particularly medically relevant proteins, through our Online Structure Request System for Researchers. They have solved many community-nominated targets and deposited information about these targets in public databases and published on our investigations and findings. Sponsors: CESG is supported by NIH / NIGMS Protein Structure Initiative grant numbers U54 GM074901 and P50 GM064598.

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• 14 years ago - by Anonymous

Software application (entry from Genetic Analysis Software)

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• 14 years ago - by Anonymous

This the homepage for the Flow Cytometers Facility in UC Berkeley. :Sponsors: This Research Facility is supported by the Cancer Research Laboratory and CIRM Human Embryonic Stem Cell Shared Research Facility at the UC Berkeley Campus. Keywords: Laboratory, Service, Testing, Assessment, Research, Flow cytometer,

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• 17 years ago - by Anonymous