Curator Dashboard

Provides support for the Apache community of open-source software projects. The Apache projects are characterized by a collaborative, consensus based development process, open and pragmatic software license, and a desire to create high quality software that leads the way in its field.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. Following completion of the acquisition of Rosetta Biosoftware assets from Merck & Co., Inc. by Microsoft Corp. on June 26, 2009, Merck & Co., Inc. selected Ceiba Solutions, Inc (http://www.ceibasolutions.com) as the provider of product support for Rosetta Resolver, Elucidator and Syllego customers. Ceiba Solutions is a software and IT services company helping customers streamline and extend business processes through composite software development, application integration, and managed application services. Ceiba currently serves Life Science industry customers with outsourced managed services for R&D applications, as well as business software and integrated business processes. Ceiba Solutions is an active member of the Massachusetts Biotechnology Council and the BayBio Council. Ceiba Solutions has assumed complete responsibility for software maintenance and support associated with Rosetta Biosoftware product Licensees who are eligible for continued Technical Support and Software Upgrade Protection, and will retain that responsibility throughout the remainder of the 24 month Desupport Period.

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• SciCrunch
• 17 years ago - by Anonymous

INB is a technological plattform of Genoma Espaa. A National Network for coordination, integration and development of Spanish Bioinformatics Resources in genomics and proteomics projects. The INB (Instituto Nacional de Bioinformtica) is a community-driven technology platform of Genoma Espana founded in 2003 with the mission to consolidate Bioinformatics as a scientific discipline and to generate and apply solutions for the development and execution of projects related to genomics and proteomics, providing technical support in Bioinformatics to laboratories, institutions and companies throughout the Spanish territory.

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• SciCrunch
• 17 years ago - by Anonymous

This collection of Free Statistics Calculators offers a wide range of descriptive and explorative types of statistical measures and analysis: Central Tendency, Average, Mean, Median, Variability, Interquartile Range, Concentration, Lorenz Curve, Gini Coefficient, Skewness, Kurtosis, Quartiles, Percentiles, Notched Boxplot, Histogram, Correlation, Partial Correlation, Rank Correlation (Spearman and Kendall), Simple Regression, Kernel Density Estimation, Harrell-Davis Quantiles, Bivariate KDE, Correlation Matrix, Stem-and-leaf plot, Explorative Data Analysis

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• SciCrunch
• 17 years ago - by Anonymous

A method to assess the outcome of nonsynonymous SNVs using a consensus deleteriousness score that combines various tools (e.g. SIFT, Polyphen2, MutationAssessor).

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• SciCrunch
• 13 years ago - by Anonymous

WDIN is a collaborative project working to develop a Web-based monitoring and reporting system to provide state and federal resource managers, animal disease specialists, veterinary diagnostic laboratories, physicians, public health workers, educators, and the general public with access to data on wildlife diseases, mortality events, and other critical related information. Data are contributed voluntarily, with partners deciding which data they choose to share.

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• SciCrunch
• 17 years ago - by Anonymous

Our principal research interest is the organization and the dynamics of the large-scale neuronal networks of the brain that characterize mental functions, and the understanding of disturbances of these networks in patients with brain dysfunctions. Electromagnetic imaging based on high-resolution EEG is our principal instrument to study these questions. It is combined with Transcranial Magnetic Stimulation (TMS), Functional Magnetic Resonance Imaging (fMRI), and multichannel intracranial recordings in patients. Sponsors: Swiss National Science Foundation Fondation Louis Jeantet de Mdecine Fondation Leenards

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• SciCrunch
• 17 years ago - by Anonymous

The DeRisi Lab focuses on genomic approaches to the study of infectious disease. Specifically, we are studying Plasmodium falciparum, the causative agent of the most deadly form of human malaria. We are also involved in a major effort for the discovery of new viral pathogens associated with diseases of unknown etiology. Software tools developed in the lab include: HMMSplicer discovers splice sites in high throughput sequencing datasets without using gene models. HMMSplicer can also be used to find non-canonical junctions as well. HMMSplicer was benchmarked on publickly available A. thaliana, H. sapiens, and P. falciparum datasets and performs well on all genomes. Information about the datasets tested, including the exact command parameters and the final results, is provided. HMMSplicer is implemented in Python and is freely available for all. VersaCount is a simple application to assist with the counting of cells by microscopy. When used with a numeric keypad, it can significantly increase counting efficiency when compared with a traditional clicker. Although it was designed for malaria work, it can be customized for a wide variety of cell counting applications. VersaCount was written by Charlie Kim. ExpressionNet is a program written by Jingchun Zhu that uses Bayesian network learning algorithms to explore relationships among random variables to generate network models. The software has been used to study the transcriptional response to environmental perturbations in budding yeast. Details of the program and the study of yeast transcription using Bayesian Networks was published in PLoS ONE. DNA microarrays may be used to identify microbial species present in environmental and clinical samples. However, automated tools for reliable species identification based on observed microarray hybridization patterns are lacking. We present an algorithm, E-Predict, for microarray-based species identification. ArrayOligoSelector (AOS) is an open source program developed by Jingchun Zhu for the purpose of systematically designing gene-specific long oligonucleotide probes for entire genomes. For each open reading frame, the program optimizes oligo selection based upon several parameters, including uniqueness, complexity, secondary structure, GC content, and 3'' end proximity. AOS also is hosted at SourceForge. This site contains documentation and a user-friendly how-to. ArrayMaker 2 provides high performance robotic control of microarrayer robots with an incredibly intuitive, easy to use interface. ArrayMaker 2 is optimized for use with the new generation of ultra fast linear servo driven arrayers, yet it is backwards compatible with the original MGuide style of ball-screw driven arrayers.

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• SciCrunch
• 17 years ago - by Anonymous

Retroelements constitute important evolutionary forces for the genome of higher organisms, yet their uncontrolled spread, whether from endogenous loci or within the context of viral infections, can cause diseases such as cancer, hepatitis and AIDS. Correspondingly, a variety of host-encoded activities limit this process, belonging to a line of defense commonly called intrinsic or innate immunity, which notably contributes to taming endogenous retroelements and to restricting the cross-species transmission of retroviruses. Our work aims at characterizing the relationship between retroelements and their hosts, which has recently led us to become more generally interested in epigenetic mechanisms regulating the expression of mammalian genomes.

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• SciCrunch
• 17 years ago - by Anonymous

A large collection of tools for basic and advanced analyses of nucleotide and protein sequences. The tools are wrapped into a common user interface making handling, storage, retrieval and viewing the results easy and logical. A seqtools project can accommodate many thousand sequences making unattended batch analyses like database searching at NCBI painless with the robust search engine included in seqtools.

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• SciCrunch
• 17 years ago - by Anonymous

SABiosciences, as part of QIAGEN, offers nucleic acid (DNA, RNA, miRNA) and protein isolation, preparation and purification services, as well as assay,array, sequencing, NGS and biomarker services and lab essentials.Offers PCR services, assays, array systems, and expression vectors. Acquired by QIAGEN in 2009.

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• SciCrunch
• 17 years ago - by Anonymous

The SABC is the collaborative university Centre for R&D in agricultural and veterinary biotechnology in Western Australia. It provides platform technologies and world class equipment and facilities for R&D in agricultural biotechnology to researchers from universities, state government and industry. More than 20 research groups and companies rent space and use the SABC facilities. It is based at Murdoch University in Perth. Our Vision To be an eminent, internationally recognized centre for research and development in agriculture and veterinary biotechnology Our Mission To provide state-of-the-art facilities and equipment enabling multi disciplinary research in biotechnology which under pins the agricultural and veterinary industry, for the benefit of the community. This will be achieved by being recognised as the centre for agricultural biotechnology in WA providing national and international research links and collaborations fostering establishment of national centres in leading edge technologies Characteristics of the SABC * The SABC is a multi-user centre with a research spend of about $9 million pa * There is a critical mass of more than 225 researchers * The SABC combines university, state government and industry researchers in one cost-effective centre * The SABC operates as a ''Research Hotel'' in which different groups rent common laboratory space and access to platform technologies * The SABC supports incubation and co-location of new ag biotech companies in WA * The SABC promotes collaborative research, undertakes contract research, and provides many local, national and international linkages * SABC researchers are members of eight agricultural Cooperative Centres (CRCs) Research Focus The research focus is on molecular activities that involve or promote primary production of commercial livestock, crop plants or microbes, or their subsequent processing for added value. The SABC also supports research in biomedical sciences, and environmental biotechnology. Deliverables and Outcomes SABC researchers have an outstanding track record of outputs and outcomes. These include the provision of co-located, state-of-the art, well run platform technologies for all WA researchers plant breeding support leading to improved crop varieties (molecular markers, yield, resistance to diseases and pests, better quality, variety ID, diagnostics), improved productivity and health of livestock, and biomedical diagnostics. Facilities and platform technologies The SABC provides the most comprehensive set of equipment and facilities for biotechnology R&D in WA, with full facilities for: cell and molecular biology, robotics, high throughput agricultural genetic analyses and diagnostics, structural, comparative and functional genomics, microarray technologies, proteomics and mass spectroscopy and bioinformatics support via the (CBBC). Training and Mentoring The SABC plays a major role in advanced training in ag biotech. There are about 100 Honours and PhD students in the research complement. The SABC also runs a series of hands on short courses in molecular biology, gene mapping, diagnostics, proteomics and bioinformatics. In 2005 new postgraduate certificate and diploma courses on Application of Molecular Technologies was established at Murdoch University, run by internationally qualified SABC researchers. These provide advanced education at the Postgraduate Certificate, Diploma and MSc levels, for local and international participants. click here for details The SABC runs the following hands-on training workshops: * Introduction to Molecular Biology * Molecular Mapping Techniques in Diagnostic Biotechnology * High Throughput Genetic Analysis * Introduction to Proteomics * Advanced Proteomics * Bioinformatics (with the CBBC) Competitive Advantages The SABC: * combines crop, veterinary and biomedical research in biotechnology in one centre * is multidisciplinary and inclusive * provides enabling facilities, platform technologies and common laboratories * is highly cost effective Researcher Groups Using the SABC * Division of Health Sciences (Murdoch)/Veterinary Sciences * Division of Science and Engineering (Murdoch)/Biological Sciences and Biotechnology * UWA (Natural Resources and Agriculture, Biochemistry) * Curtin University (Molecular Biotechnology, Horticulture) * Edith Cowan University (Human Genetics) * WA Dept of Agriculture (animal, plant, microbial) * Fisheries * Perth Zoo * Plant Biotechnology Research Group * Australian Centre for Necrotrophic Fungal Pathogens (ACNFP) * Rumen Biotechnology * Centre for High Throughput Agricultural Genetic Analysis (CHAGA) * Veterinary Virology, Parasitology, Microbiology * Saturn Biotech Pty Ltd * Grain Biotech Australia Pty Ltd * Proteomics International * Lighthouse Laboratories Pty Ltd * ID PLUS Pty Ltd * Royal Perth Hospital * Fremantle Hospital * Australian Neuromuscular Research Institute (ANRI) Partnering Opportunities The SABC can provide full facilities for contract R&D, start up companies or co-location of existing companies in agricultural, veterinary and biomedical sciences via its incubation program. Contact the Director for further information. Partnering Needs Investors interested in commercializing outputs of SABC researchers.

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• SciCrunch
• 17 years ago - by Anonymous

Software products and services for behavioral and physiological research, including control software for experiments on primates and rodents, analysis of electrophysiological data, display of visual and auditory stimuli, and synchronization of experimental data from other measurement devices. The company offers a range of consulting services and provides product support services that assist customers in developing, deploying, and managing custom behavioral testing programs.

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• SciCrunch
• 17 years ago - by Anonymous

Rules-Based Medicine (RBM) uses proprietary Multi-Analyte Profiling (MAP) technology to make life science research and drug and diagnostic development programs more efficient and effective. Whether measuring hundreds of biomarkers or simply a few, our approach provides reproducible, quantitative immunoassay data from a small sample volume at a cost-effective price. RBM is CLIA certified and supports GLP studies. * Quality: All immunoassays are validated to clinical laboratory standards. This means complete validation for the clinic, not fit for purpose validation which at RBM means inferior validation. Learn More * Content: We have the most comprehensive menu of biomarker immunoassays available. * Small Sample Volumes: Multiplexing provides you with more data using a smaller sample volume. * Cost Effective: Multiplexing and automation combine to deliver high quality data at reasonable prices. * Ease of use: Ship us your samples and get results within 2 weeks. Rules-Based Medicine (RBM), the worlds leading multiplexed biomarker testing laboratory, provides comprehensive protein biomarker products and services based on its Multi-Analyte Profiling (MAP) technology platform. RBMs biomarker testing service provides pre-clinical and clinical researchers with reproducible, quantitative, multiplexed immunoassay data for hundreds of proteins in a cost-effective manner, from a small sample volume and from multiple species. Our biomarker testing laboratory is CLIA certified and supports GLP studies. Most diseases and drug effects manifest themselves in abnormal levels of specific biomarkers found in the peripheral blood. By providing multiplexed, quantitative, and reproducible tests for hundreds of biomarkers, RBM enables research that historically was not available due to sample volume requirements and associated costs. Use of our testing services can identify the sources of both the positive and negative effects of drugs during pre-clinical research and clinical trials. Biomarker testing results identify patients most likely to respond to a given therapy and the biochemical reason for that response, making clinical trials more successful and effective. Through its wholly owned subsidiary EDI GmbH, RBM provides Human Organo-Typic (HOT) cell culture systems. These co-culture systems consist of multiple primary cell types grown in a 3-D architecture that closely mimic particular human organs and are an ideal platform for ex vivo studies of drug safety and efficacy. RBM combines EDIs cell culture systems with its HumanMAP biomarker testing services to provide researchers with an unprecedented view of the physiological and biochemical impact of a new drug compound or consumer product prior to testing in a human subject. RBM also performs custom assay development, participates in co-sponsored research programs, and pursues in-licensing of novel high-value assays.

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• SciCrunch
• 17 years ago - by Anonymous

The Royal Ontario Museum is among the worlds leading museums of natural history, and of world cultures. Indeed, in combining a universal museum of cultures with that of natural history, the ROM offers an unusual breadth of experience to visitors and scholars from around the world. We realize more acutely now that nature and humanity are intertwined, and the ROM offers many examples in its collections and programs of these fundamental relationships. It is the ROMs mission to engage the public in exploration of cultural change and to serve as an advocate for science in the study of nature. Our collections and research serve as the basis for programs ranging from formal student education courses to public debates, lectures, symposia, films, tours, publications, travel and family activities. The museum aims to host and produce programs of intellectual depth and social relevance on both sides of its mandate, including unique ROM exhibitions and works of a collaborative nature. Through the ROMs Institute for Contemporary Culture, the museum also explores current issues through works of art and programs in many media. The ROM is near completion of a major capital project (Renaissance ROM) that will see the building of 27 new galleries, the liberation of many stranded collections, the addition of valuable public amenities, and the creation of dramatic new architecture in the Michael Lee-Chin Crystal, designed by Daniel Libeskind. This is among the largest capital projects in the history of Canadian cultural institutions, and brings the assets of the museum fully to the public again even as the ROM prepares to celebrate its centenary in 2014. On this website, you have access to thousands of photographs and summaries from the ROMs collections, results of its research activities around the world, information on current programs and exhibitions, and means to download information, watch podcasts and purchase tickets to the museum and its events. You will also find information about its restaurants, the ROM Museum Store and rental services for ROM facilities after hours. The Royal Ontario Museum offers a unique platform to the engage the worlds of culture and the environment at the centre of one of North Americas great cities. We look forward to meeting you here, and to sharing the adventures of this place, with all its treasures.

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• SciCrunch
• 17 years ago - by Anonymous

The Centre for Automotive Safety Research at the University of Adelaide, is internationally recognised as a leading research organisation in its field. The Centre conducts high quality independent research that enables rational decision making, leading to a reduction in the human and economic losses from road crashes. The Centre is focused on: * Conducting multidisciplinary research to understand how road crashes and the resulting injuries are caused * Proposing and evaluating ways to prevent crashes and injuries * Providing independent professional advice on road safety matters to government and non-government organisations in Australia and overseas The Centre began life in 1973 as the Road Accident Research Unit (RARU) with the planning and undertaking of an in-depth study of road accidents in the Adelaide metropolitan area. From 1981 through 1998, the Unit''s work was supported by a grant from the National Health And Medical Research Council. During that grant period RARU''s research program was concentrated in two areas: the study of brain injury mechanisms in fatally injured road users and the epidemiology of drink driving and alcohol related crashes. Notably, an investigation of the influence of vehicle speed in fatal pedestrian accidents led on to case control studies of the relationship between a driver''s travelling speed and risk of involvement in a casualty crash in both urban and rural areas. RARU''s analysis of the occurrence of brain injury in road crashes called into question the then prevailing paradigm of brain injury mechanisms. This prompted the development of an experimental study of axonal injury that, in turn, led to the Japan Automobile Research Institute initiating a formal collaborative research agreement with RARU, and now with CASR, in the area of crash injury biomechanics. Also a part of our legacy is that over 40 years ago the Centre''s previous Director, Professor Jack McLean, co-authored the first paper in the world to show that car design played a major role in pedestrian protection, revealing that pedestrians are run under, not over, by the striking car.

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• SciCrunch
• 17 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Rosetta Inpharmatics in Seattle, WA Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co. Inc., develops and implements technologies that will improve drug discovery. The company''s leading-edge genomic research and data analysis efforts focus on how medical compounds affect biology, enabling more accurate selection of drug targets and more efficient drug development. Rosetta Inpharmatics was founded in 1996 to design and implement DNA microarray gene expression technologies.

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• SciCrunch
• 17 years ago - by Anonymous

Roche NimbleGen, Inc. is a leading innovator, manufacturer and supplier of a proprietary suite of DNA microarrays, consumables, instruments and services. Roche NimbleGen uniquely produces high-density arrays of long oligo probes that provide greater information content and higher data quality necessary for studying the full diversity of genomic and epigenomic variation. Roche NimbleGen is enabling a new era of High-Definition Genomics by providing scientists with cost-effective, high-throughput tools for extracting and integrating complex data on important forms of genomic and epigenomic variation not previously accessible on a genome-wide scale. Scientists can thus obtain a clearer understanding of genomic and epigenomic structure and function and how they impact biology and medicine. This improved performance is made possible by Roche NimbleGen''s proprietary Maskless Array Synthesis (MAS) technology, which uses digital light processing and rapid, high-yield photochemistry to synthesize long oligo, high-density DNA microarrays with extreme flexibility. NimbleGen Systems was established in 1999. The MAS technology is the result of research collaborations between the departments of biotechnology, genetics, physics, and semiconductor engineering at the University of Wisconsin - Madison. Roche NimbleGen has the exclusive worldwide license to the MAS technology from the Wisconsin Alumni Research Foundation (WARF).

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• SciCrunch
• 17 years ago - by Anonymous

Organization that facilitates spinal cord injury research and care. By accelerating the translation of discoveries and best practices into improved treatments, it aims to improve the lives of people living with SCI.

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• SciCrunch
• 14 years ago - by Anonymous

Resources for macromolecular X-ray crystallography from the Richardson Laboratory, including kinemages (a scientific illustration presented as an interactive computer display), databases, software, training materials and images

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• SciCrunch
• 17 years ago - by Anonymous