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Purpose of the Myc Hubsite The emergence of complex DNA microarray data on gene expression creates vast new opportunities but also poses serious challenges for information and library sciences. This complexity becomes more challenging as certain genes, such as MYC that encodes a transcription factor, switch on other genes. The purpose of this website is to provide a hub for the integration of information on Myc target genes, the role of Myc in human cancers, and proteins that interact with the Myc transcription factors. Links are provided that connect to PUBMED citations, Unigene database, and in specific cases to original data. Sponsor: Funded by a grant from the National Library of Medicine

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• SciCrunch
• 17 years ago - by Anonymous

The LVC64 accepts 64 microvolt-level buffered input signals from headstage preamps and serves as a 24-bit recording device. It is connected to a PC with an USB2.0 cable and provides a complete digital system to record broadband bioelectric signals. It has two parts such as a 64-channel ADC unit and a digital interface & power supply unit. Between these units there is a slip ring commutator and a DC motor. The main features of the LVC system include: Up to 128 Analog inputs per system; Each Analog input is sampled with an individual 24 bit delta-sigma A/D converter Analog inputs are simultaneously sampled at 1750 to 32000 samples per second In addition to multiple unit activity - the EEG, field potentials and behavioral marker signals are recorded simultaneously in the same file Full scale analog input range is 5 millivolts RMS (14 mV peak-to-peak) Analog inputs are differential inputs Extremely low input referred noise levels of max. 8 uV peak-to-peak Direct headstage tether and tether extension cable inputs Slip ring commutator for un-twisting the twisted tether cable Headstage power supplies Up to 24 bit TTL compatible Parallel Input Port for monitoring external signals and external Timestamp Clock input and output for multiple system synchronization Totally electrically isolated system from AC Power and Ground ''Microvolts-to-harddisk dumper'' data acquisition program running in host PC (32-bit MS Window XP) Online display of records during data acquisition in Host PC''s monitor Offline spike sorting by Cooperative Linux software of the Host PC

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• SciCrunch
• 17 years ago - by Anonymous

Blender is the free open source 3D content creation suite, available for all major operating systems under the GNU General Public License. Because of the overwhelming success of the first open movie project, Ton Roosendaal, the Blender Foundation''s chairman, has established the Blender Institute. This now is the permanent office and studio to more efficiently organize the Blender Foundation goals, but especially to coordinate and facilitate Open Projects related to 3D movies, games or visual effects.

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• SciCrunch
• 17 years ago - by Anonymous

Welcome to the Anopheles gambiae Gene Expression Database at UC Irvine. Presented here is a relational database that combines data from microarray experiments, functional annotation, and the An. gambiae genome project to provide insight into gene expression and regulation in this mosquito vector of human malaria. Microarray analyses included in this site were based on the Affymetrix GeneChip Plasmodium/Anopheles Genome Array. Abundance of specific mRNAs represented in the array were determined for larvae (3rd and 4th instars), adult males (3 days post emergence), non-blood fed females (3 days post emergence) and females at 3, 24, 48, 72, and 96 hours following a blood meal, and females aged 18 days with or without a bloodmeal. Functional annotation integrated into the site for keyword searching combines keywords indexed in the ENSEMBL Mosquito Genome database, NCBI non-redundant databases and conserved motifs databases (GO, PFAM, SMART). Sequence data was captured from the ENSEMBL Mosquito Genome database.

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• SciCrunch
• 17 years ago - by Anonymous

Welcome to the Air Force Suicide Prevention Program (AFSPP) Website. This site is designed to provide information and tools to members of the Air Force community (Suicide Prevention Program Managers, commanders, gatekeepers, IDS members, etc.) in their efforts to help reduce Air Force suicides. Reducing suicide requires a community effort and we welcome your visit to our site.<BR/>

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• SciCrunch
• 17 years ago - by Anonymous

MMV, a not-for-profit public-private partnership, was established as a foundation in Switzerland in 1999. Our mission is to reduce the burden of malaria in disease-endemic countries by discovering, developing and facilitating delivery of new, effective and affordable antimalarial drugs. Our vision is a world in which these innovative medicines will cure and protect the vulnerable and under-served populations at risk of malaria, and help to ultimately eradicate this terrible disease. Sponsors/Donors: -Bill and Melinda Gates Foundation -CRIMALDDI -ExxonMobil -Irish Aid -National Institutes of Health -Netherlands Ministry of Foreign Affairs -Rockefeller Foundation (former donor) -Secretaria de Estado de Cooperacin Internacional (Spanish Agency for International Cooperation) -Swiss Agency for Development and Cooperation -UK Department for International Development -USAID -Wellcome Trust -World Bank -World Health Organization

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• SciCrunch
• 17 years ago - by Anonymous

Founded in 1981, ZymoGenetics is a biopharmaceutical company focused on the development and commercialization of therapeutic proteins. ZymoGenetics is publicly traded (NASDAQ: ZGEN) and headquartered in Seattle, Washington in the historic Seattle City Light Steam Plant building. Our mission is to create novel protein drugs that will significantly help patients fight their diseases. We have contributed to the discovery or development of six recombinant protein products now marketed by other companies. Current programs target viral infection, cancer, inflammatory diseases and bleeding. Our first internally developed product, RECOTHROM Thrombin, topical (Recombinant), was approved by the U.S. Food and Drug Administration (FDA) on January 17, 2008 for use as a topical hemostat to control moderate bleeding during surgical procedures and is now marketed in the United States. We have a promising pipeline of novel therapeutics, which we are developing on our own or in collaboration with partners.

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• SciCrunch
• 17 years ago - by Anonymous

Zoomify makes high-quality images zoom-and-pan for fast, interactive viewing on the web. Zoomify''s image viewing solutions use just HTML, JPEGs, and Flash - no large downloads, no special installs, and no server-side setup is required. And Zoomify''s innovative features provided added value including support for slideshows, hotspots, annotation, side-by-side comparison, and much more. Zoomifys products meet the high-quality, high-resolution imaging needs of creative professionals and image-centric applications. Zoomify is revolutionizing digital imaging in medicine and the sciences, image archiving and museum exhibits, defense and security, education, entertainment, and more.

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• SciCrunch
• 17 years ago - by Anonymous

A free web server for the analysis of short RNAs from high throughput sequencing data.

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• 13 years ago - by Anonymous

Computational tool developed to help identify cancer-associated ''driver'' mutations from ''passenger'' ones in a cancer genome.

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• SciCrunch
• 13 years ago - by Anonymous

This site provides several tools for selecting zinc finger protein (ZFP) target sites and for designing the proteins that will target them. These ZFPs can be fused with effector domains that confer transcriptional activation or repression activity as well as catalytic functions.

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• SciCrunch
• 17 years ago - by Anonymous

Aquatic Habitats (AHAB) is the worlds largest manufacturer of housing systems for aquatic research animals. We are biologists first and engineers second, so we understand the complexity of aquatic life and how to sustain it. Our turnkey systems are secure, efficient and as fail-safe as possible.<BR/>

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• SciCrunch
• 17 years ago - by Anonymous

Welcome to ZINC, a free database of commercially-available compounds for virtual screening. ZINC contains over 13 million purchasable compounds in ready-to-dock, 3D formats. ZINC is provided by the Shoichet Laboratory in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF). To cite ZINC, please reference: Irwin and Shoichet, J. Chem. Inf. Model. 2005;45(1):177-82 PDF, DOI. We thank NIGMS for financial support (GM71896). There are release notes for ZINC 10. - We have a survey where you can give us feedback.

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• SciCrunch
• 17 years ago - by Anonymous

ZF-MODELS - Zebrafish Models for Human Development and Disease is an Integrated Project funded by the European Commission as part of its Sixth Framework Programme (EC Contract LSHG-CT-2003-503496). The project started on January 1, 2004 and is scheduled to run over a period of five years. The aim of this project is to exploit the advantages of the zebrafish to produce knowledge, technology and materials in the form of disease models, drug targets and insight into pathways of gene regulation applicable to human development and disease.

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• SciCrunch
• 17 years ago - by Anonymous

The YUI Library is a set of utilities and controls, written with JavaScript and CSS, for building richly interactive web applications using techniques such as DOM scripting, DHTML and AJAX. YUI is available under a BSD license and is free for all uses. YUI is proven, scalable, fast, and robust. Built by frontend engineers at Yahoo! and contributors from around the world, it''s an industrial-strength JavaScript library for professionals who love JavaScript.

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• SciCrunch
• 17 years ago - by Anonymous

Provides equipment for TEER measurement, nitric oxide testing, and electro-physiology applications.

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• SciCrunch
• 17 years ago - by Anonymous

An organization that promotes the highest possible standards of medical ethics. The WMA provides ethical guidance to physicians through its Declarations, Resolutions and Statements. These also help to guide National Medical Associations, governments and international organizations throughout the world. The Declarations, Resolutions and Statements cover a wide range of subjects, including an International Code of Medical Ethics, the rights of patients, research on human subjects, care of the sick and wounded in times of armed conflict, torture of prisoners, the use and abuse of drugs, family planning and pollution.

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• SciCrunch
• 17 years ago - by Anonymous

A substantial biological challenge is to understand the regulation and execution of developmental decisions that lead from multipotential, undifferentiated precursor cells to their specialized differential products. In the World lab at the California Institute of Technology, we are interested in several interrelated aspects of this problem, and we also work to develop new methods for studying it. The particular cell lineage problem we study begins with the specification of mesoderm in early development and continues to the final differentiation of skeletal muscle or cardiac muscle in the fully developed animal. To study this process we use the mouse as our experimental system. Molecular-level analyses use cell culture model systems and transgenic mice. These projects include studies of in vitro and in vivo protein-DNA interactions and of factors that amplify or suppress expression activity. Computational approaches involve the development of algorithms for use in large-scale gene expression analysis and the construction of a simulator framework for regulation in muscle development.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on Jan 16th 2025. WinLTP is a stimulation, data acquisition and on-line analysis electrophysiological software for studying Long-Term Potentiation (LTP), Long-term Depression (LTD), and related phenomena. WinLTP is multitasking and simultaneously runs 1) LTP stimulus/acquisition/analyzing sweeps with protocol scripting, and 2) continuous acquisition saving Axon Binary Files (abf). WinLTP runs on Windows PCI bus computers and uses National Instruments PCI M-Series boards and Axon Instruments'' Digidata 1320A and 1322A data acquisition boards. Other software that can use the M-Series boards includes Axograph Scientific''s AxoGraph X, WaveMetrics'' IGOR, National Instruments'' LabView, John Dempster''s Strathclyde Electrophysiology Suite (WinWCP and WinEDR), Silver lab''s Nclamp, and QUB data acquisition., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 17 years ago - by Anonymous

Bioinformatics, statistical genetics, functional genomics, databases and scientific computing support and services for The Wellcome Trust Centre for Human Genetics to support the disease gene cloning projects within the centre and to maintain independent research in development of methods, algorithms and software for mapping multifactorial trait loci. The group has current research foci in the areas of sequence alignment statistics, comparative genomics, ancestral haplotype construction, LIMS database development, QTL linkage and association methods, variability in patterns of linkage disequilibrium and multivariate modelling of quantitative traits.

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• SciCrunch
• 17 years ago - by Anonymous