URL: http://pringlelab.stanford.edu/projects.html
Proper Citation: Fulcrum (RRID:SCR_005523)
Description: Software to collapse identical and near-identical Illumina and 454 reads (such as those from PCR clones) into single error-corrected sequences; it can process paired-end as well as single-end reads. Fulcrum is customizable and can be deployed on a single machine, a local network or a commercially available MapReduce cluster, and it has been optimized to maximize ease-of-use, cross-platform compatibility and future scalability. Sequence datasets have been collapsed by up to 71%, and the reduced number and improved quality of the resulting sequences allow assemblers to produce longer contigs while using less memory.
Abbreviations: Fulcrum
Synonyms: Fulcrum Read Collapser
Resource Type: software resource
Defining Citation: PMID:22419786
Keywords: illumina, 454, read, paired-end read, single-end read, high-throughput sequencing, redundant read, genome, transcriptome, ultra high throughput sequencing
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